Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques

Ajay A. Madhavan; Zhongxing Zhou; Paul J. Farnsworth; Jamison Thorne; Timothy J. Amrhein; Peter G. Kranz; Waleed Brinjikji; Jeremy K. Cutsforth-Gregory; Michelle L. Kodet; Nikkole M. Weber; Grace Thompson; Felix E. Diehn; Lifeng Yu

doi:10.3174/ajnr.A8695

Research ArticleSPINE IMAGING AND SPINE IMAGE-GUIDED INTERVENTIONS

Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques

Ajay A. Madhavan, Zhongxing Zhou, Paul J. Farnsworth, Jamison Thorne, Timothy J. Amrhein, Peter G. Kranz, Waleed Brinjikji, Jeremy K. Cutsforth-Gregory, Michelle L. Kodet, Nikkole M. Weber, Grace Thompson, Felix E. Diehn and Lifeng Yu

American Journal of Neuroradiology June 2025, DOI: https://doi.org/10.3174/ajnr.A8695

Ajay A. Madhavan

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Zhongxing Zhou

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Paul J. Farnsworth

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Jamison Thorne

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Timothy J. Amrhein

bDepartment of Radiology (T.J.A., P.G.K.), Duke Health, Durham, North Carolina

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Peter G. Kranz

bDepartment of Radiology (T.J.A., P.G.K.), Duke Health, Durham, North Carolina

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Waleed Brinjikji

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Jeremy K. Cutsforth-Gregory

cDepartment of Neurology (J.K.C.-G.), Mayo Clinic, Rochester, Minnesota.

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Michelle L. Kodet

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Nikkole M. Weber

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Grace Thompson

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Felix E. Diehn

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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Lifeng Yu

aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota

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DOI

https://doi.org/10.3174/ajnr.A8695

PubMed

39929540

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American Journal of Neuroradiology

Print ISSN

0195-6108

Online ISSN

1936-959X

History

Received December 15, 2024
Accepted after revision February 4, 2025
Published online June 19, 2025.

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Latest version (February 10, 2025 - 06:56).
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Ajay A. Madhavana,
Zhongxing Zhoua,
Paul J. Farnswortha,
Jamison Thornea,
Timothy J. Amrheinb,
Peter G. Kranzb,
Waleed Brinjikjia,
Jeremy K. Cutsforth-Gregoryc,
Michelle L. Kodeta,
Nikkole M. Webera,
Grace Thompsona,
Felix E. Diehna and
Lifeng Yua

^aFrom the Department of Radiology (A.A.M., ZZ., P.J.F., J.T., W.B., M.L.K., N.M.W., G.T., F.E.D., L.Y.), Mayo Clinic, Rochester, Minnesota
^bDepartment of Radiology (T.J.A., P.G.K.), Duke Health, Durham, North Carolina
^cDepartment of Neurology (J.K.C.-G.), Mayo Clinic, Rochester, Minnesota.

Please address correspondence to Ajay Madhavan, MD, Division of Neuroradiology, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905; e-mail: madhavan.ajay{at}mayo.edu; @AjayMadhavanMD

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Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques

American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8695

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Optimization of Photon Counting CT Myelography

American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8695

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Optimization of Photon-Counting CT Myelography for the Detection of CSF-Venous Fistulas Using Convolutional Neural Network Denoising: A Comparative Analysis of Reconstruction Techniques

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