Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Sign up to receive an email alert when a new Case of the Week is posted.
June 1, 2009
Marchiafava-Bignami Disease
- Primary degeneration of the corpus callosum associated with chronic alcohol consumption but occasionally seen in nonalcoholic patients.
- Patients present acutely with confusion, disorientation, neurocognitive deficits and seizures; in contrast, the chronic form is characterized by chronic dementia.
- The acute form affects the genu and splenium, whereas the chronic form most commonly affects the body.
- Diagnosis is made on the basis of clinical findings in combination with imaging features.
Current Issue
Case Collections
