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Research ArticleArtificial Intelligence

Empowering Data Sharing in Neuroscience: A Deep Learning Deidentification Method for Pediatric Brain MRIs

Ariana M. Familiar, Neda Khalili, Nastaran Khalili, Cassidy Schuman, Evan Grove, Karthik Viswanathan, Jakob Seidlitz, Aaron Alexander-Bloch, Anna Zapaishchykova, Benjamin H. Kann, Arastoo Vossough, Phillip B. Storm, Adam C. Resnick, Anahita Fathi Kazerooni and Ali Nabavizadeh
American Journal of Neuroradiology May 2025, 46 (5) 964-972; DOI: https://doi.org/10.3174/ajnr.A8581
Ariana M. Familiar
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Neda Khalili
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Nastaran Khalili
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Cassidy Schuman
cSchool of Engineering and Applied Science (C.S., E.G.), University of Pennsylvania, Philadelphia, Pennsylvania
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Evan Grove
cSchool of Engineering and Applied Science (C.S., E.G.), University of Pennsylvania, Philadelphia, Pennsylvania
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Karthik Viswanathan
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Jakob Seidlitz
dDepartment of Child and Adolescent Psychiatry and Behavioral Science (J.S., A.A.-B.), The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
eDepartment of Psychiatry (J.S., A.A.-B.), University of Pennsylvania, Philadelphia, Pennsylvania
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Aaron Alexander-Bloch
dDepartment of Child and Adolescent Psychiatry and Behavioral Science (J.S., A.A.-B.), The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
eDepartment of Psychiatry (J.S., A.A.-B.), University of Pennsylvania, Philadelphia, Pennsylvania
f Lifespan Brain Institute at the Children’s Hospital of Philadelphia and University of Pennsylvania (A.A.-B.), Philadelphia, Pennsylvania
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Anna Zapaishchykova
gArtificial Intelligence in Medicine (AIM) Program (A.Z., B.H.K.), Mass General Brigham, Harvard Medical School, Boston, Massachusetts
hDepartment of Radiation Oncology (A.Z., B.H.K.), Dana-Farber Cancer Institute and Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
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Benjamin H. Kann
gArtificial Intelligence in Medicine (AIM) Program (A.Z., B.H.K.), Mass General Brigham, Harvard Medical School, Boston, Massachusetts
hDepartment of Radiation Oncology (A.Z., B.H.K.), Dana-Farber Cancer Institute and Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
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Arastoo Vossough
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
iDivision of Radiology (A.V.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
jDepartment of Radiology, Perelman School of Medicine (A.V., A.N.), University of Pennsylvania, Philadelphia, Pennsylvania
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Phillip B. Storm
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Adam C. Resnick
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Anahita Fathi Kazerooni
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bDepartment of Neurosurgery (A.M.F., Neda K., Nastaran K., K.V., P.B.S., A.C.R., A.F.K), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
kAI2D Center for AI and Data Science for Integrated Diagnostics (A.F.K.), University of Pennsylvania, Philadelphia, Pennsylvania
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Ali Nabavizadeh
aFrom the Center for Data-Driven Discovery in Biomedicine (D3b) (A.M.F., Neda K., Nastaran K., K.V., A.V., P.B.S., A.C.R., A.F.K., A.N.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
jDepartment of Radiology, Perelman School of Medicine (A.V., A.N.), University of Pennsylvania, Philadelphia, Pennsylvania
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American Journal of Neuroradiology: 46 (5)
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Vol. 46, Issue 5
1 May 2025
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Cite this article
Ariana M. Familiar, Neda Khalili, Nastaran Khalili, Cassidy Schuman, Evan Grove, Karthik Viswanathan, Jakob Seidlitz, Aaron Alexander-Bloch, Anna Zapaishchykova, Benjamin H. Kann, Arastoo Vossough, Phillip B. Storm, Adam C. Resnick, Anahita Fathi Kazerooni, Ali Nabavizadeh
Empowering Data Sharing in Neuroscience: A Deep Learning Deidentification Method for Pediatric Brain MRIs
American Journal of Neuroradiology May 2025, 46 (5) 964-972; DOI: 10.3174/ajnr.A8581

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An AI De-identification Method for Pediatric MRIs
Ariana M. Familiar, Neda Khalili, Nastaran Khalili, Cassidy Schuman, Evan Grove, Karthik Viswanathan, Jakob Seidlitz, Aaron Alexander-Bloch, Anna Zapaishchykova, Benjamin H. Kann, Arastoo Vossough, Phillip B. Storm, Adam C. Resnick, Anahita Fathi Kazerooni, Ali Nabavizadeh
American Journal of Neuroradiology May 2025, 46 (5) 964-972; DOI: 10.3174/ajnr.A8581
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