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Research ArticlePediatric Neuroimaging

MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1

A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent and D. Mata-Mbemba
American Journal of Neuroradiology August 2022, 43 (8) 1196-1201; DOI: https://doi.org/10.3174/ajnr.A7574
A. Trasolini
aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada
bDalhousie University Medical School (A.T.), Halifax, Nova Scotia, Canada
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C. Erker
aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada
cDepartments of Pediatrics (C.E.)
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S. Cheng
gDivision of Hematology, Oncology, and Bone Marrow Transplant (S.C.), Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada
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C. Crowell
aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada
fFaculty of Science (C.C.), Dalhousie University, Halifax, Nova Scotia, Canada
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K. McFadden
aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada
dPathology (K.M.)
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R. Moineddin
hUniversity of Toronto Dalla Lana School of Public Health (R.M.), Toronto, Ontario, Canada
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M.A. Sargent
iDepartment of Radiology (M.A.S.), British Columbia Children’s Hospital and University of British Columbia, Vancouver, British Columbia, Canada
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D. Mata-Mbemba
aFrom the IWK Health Centre (A.T., C.E., C.C., K.M., D.M.-M.), Halifax, Nova Scotia, Canada
eDiagnostic Radiology (D.M.-M.)
jDepartment of Diagnostic Imaging (D.M.-M.), IWK Health Centre, Halifax, Nova Scotia, Canada
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American Journal of Neuroradiology: 43 (8)
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A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent, D. Mata-Mbemba
MR Imaging of Pediatric Low-Grade Gliomas: Pretherapeutic Differentiation of BRAF V600E Mutation, BRAF Fusion, and Wild-Type Tumors in Patients without Neurofibromatosis-1
American Journal of Neuroradiology Aug 2022, 43 (8) 1196-1201; DOI: 10.3174/ajnr.A7574

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MRI of PEDS Low-Grade Gliomas and BRAF
A. Trasolini, C. Erker, S. Cheng, C. Crowell, K. McFadden, R. Moineddin, M.A. Sargent, D. Mata-Mbemba
American Journal of Neuroradiology Aug 2022, 43 (8) 1196-1201; DOI: 10.3174/ajnr.A7574
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  • Imaging Clusters of Pediatric Low-Grade Glioma Are Associated with Distinct Molecular Characteristics
  • CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis
  • Multiparametric MRI Along with Machine Learning Informs on Molecular Underpinnings, Prognosis, and Treatment Response in Pediatric Low-Grade Glioma
  • Imaging Clusters of Pediatric Low-Grade Glioma are Associated with Distinct Molecular Characteristics
  • Identification of Multiclass Pediatric Low-Grade Neuroepithelial Tumor Molecular Subtype with ADC MR Imaging and Machine Learning
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