Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain Tumor Imaging

Do We Need Gadolinium-Based Contrast Agents for Routine MRI Surveillance of Unoperated Pituitary Macroadenoma?

A.A. Alali, P.B. Hanagandi and P.J. Maralani
American Journal of Neuroradiology July 2022, 43 (7) 1024-1028; DOI: https://doi.org/10.3174/ajnr.A7554
A.A. Alali
aFrom the Division of Neuroradiology (A.A.A.), King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.A. Alali
P.B. Hanagandi
bDepartment of Medical Imaging (P.B.H.), King Abdulaziz Medical City NGHA, Riyadh, Saudi Arabia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for P.B. Hanagandi
P.J. Maralani
cDivision of Neuroradiology (P.J.M.), Department of Medical Imaging, University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for P.J. Maralani
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Ezzat S,
    2. Asa SL,
    3. Couldwell WT, et al
    . The prevalence of pituitary adenomas: a systematic review. Cancer 2004;101:613–19 doi:10.1002/cncr.20412 pmid:15274075
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Aljabri KS,
    2. Bokhari SA,
    3. Assiri FY, et al
    . The epidemiology of pituitary adenomas in a community-based hospital: a retrospective single center study in Saudi Arabia. Ann Saudi Med 2016;36:341–45 doi:10.5144/0256-4947.2016.341 pmid:27710986
    CrossRefPubMed
  3. 3.↵
    1. Hussein SH,
    2. Wahedi TS,
    3. Johani NA, et al
    . Clinical and epidemiological characteristics of pituitary tumours in a single centre in Saudi Arabia. Hormones (Athens) 2018;17:261–67 doi:10.1007/s42000-018-0030-8 pmid:29858852
    CrossRefPubMed
  4. 4.↵
    Committee on Drugs and Contrast Media. ACR Manual on Contrast Media. 2021: American College of Radiology. 2021. https://www.acr.org/-/media/ACR/Files/Clinical-Resources/Contrast_Media.pdf.
  5. 5.↵
    1. Granata V,
    2. Cascella M,
    3. Fusco R, et al
    . Immediate adverse reactions to gadolinium-based MR contrast media: a retrospective analysis on 10,608 examinations. Biomed Res Int 2016;2016:3918292 doi:10.1155/2016/3918292 pmid:27652261
    CrossRefPubMed
  6. 6.↵
    1. Stojanov D,
    2. Aracki-Trenkic A,
    3. Benedeto-Stojanov D
    . Gadolinium deposition within the dentate nucleus and globus pallidus after repeated administrations of gadolinium-based contrast agents: current status. Neuroradiology 2016;58:433–41 doi:10.1007/s00234-016-1658-1 pmid:26873830
    CrossRefPubMed
  7. 7.↵
    1. Kanda T,
    2. Ishii K,
    3. Kawaguchi H, et al
    . High signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted MR images: relationship with increasing cumulative dose of a gadolinium-based contrast material. Radiology 2014;270:834–41 doi:10.1148/radiol.13131669 pmid:24475844
    CrossRefPubMed
  8. 8.↵
    1. Kanda T,
    2. Osawa M,
    3. Oba H, et al
    . High signal intensity in dentate nucleus on unenhanced T1-weighted MR images: association with linear versus macrocyclic gadolinium chelate administration. Radiology 2015;275:803–09 doi:10.1148/radiol.14140364 pmid:25633504
    CrossRefPubMed
  9. 9.↵
    1. Quattrocchi CC,
    2. Mallio CA,
    3. Errante Y, et al
    . Gadodiamide and dentate nucleus T1 hyperintensity in patients with meningioma evaluated by multiple follow-up contrast-enhanced magnetic resonance examinations with no systemic interval therapy. Invest Radiol 2015;50:470–72 doi:10.1097/RLI.0000000000000154 pmid:25756685
    CrossRefPubMed
  10. 10.↵
    1. Gulani V,
    2. Calamante F,
    3. Shellock FG
    , et al; International Society for Magnetic Resonance in Medicine. Gadolinium deposition in the brain: summary of evidence and recommendations. Lancet Neurol 2017;16:564–70 doi:10.1016/S1474-4422(17)30158-8 pmid:28653648
    CrossRefPubMed
  11. 11.↵
    1. Knosp E,
    2. Steiner E,
    3. Kitz K, et al
    . Pituitary adenomas with invasion of the cavernous sinus space: a magnetic resonance imaging classification compared with surgical findings. Neurosurgery 1993;33:610–17; discussion 617–18 doi:10.1227/00006123-199310000-00008 pmid:8232800
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Koo TK,
    2. Li MY
    . A guideline of selecting and reporting intraclass correlation coefficients for reliability research. J Chiropr Med 2016;15:155–63 doi:10.1016/j.jcm.2016.02.012 pmid:27330520
    CrossRefPubMed
  13. 13.↵
    1. Landis JR,
    2. Koch GG
    . The measurement of observer agreement for categorical data. Biometrics 1977;33:159–74 doi:10.2307/2529310 pmid:843571
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Levy MJ,
    2. Robertson IJ,
    3. Khalk N, et al
    . Long-term follow-up of a large prospective cohort of patients with nonfunctioning pituitary adenomas: the outcome of a conservative management policy. Clin Endocrinol (Oxf) 2018;89:354–59 doi:10.1111/cen.13791 pmid:29920729
    CrossRefPubMed
  15. 15.↵
    1. Ogiwara T,
    2. Nagm A,
    3. Nakamura T, et al
    . Significance and indications of surgery for asymptomatic nonfunctioning pituitary adenomas. World Neurosurg 2019;128:e752–59 doi:10.1016/j.wneu.2019.04.250 pmid:31077893
    CrossRefPubMed
  16. 16.↵
    1. Molitch ME
    . Pituitary tumours: pituitary incidentalomas. Best Pract Res Clin Endocrinol Metab 2009;23:667–75 doi:10.1016/j.beem.2009.05.001 pmid:19945030
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Kim JH,
    2. Dho YS,
    3. Kim YH, et al
    . Developing an optimal follow-up strategy based on the natural history of nonfunctioning pituitary adenomas. J Neurosurg 2019;131:500–06 doi:10.3171/2018.4.JNS172148 pmid:30215565
    CrossRefPubMed
  18. 18.↵
    1. Dekkers OM,
    2. Pereira AM,
    3. Romijn JA
    . Treatment and follow-up of clinically nonfunctioning pituitary macroadenomas. J Clin Endocrinol Metab 2008;93:3717–26 doi:10.1210/jc.2008-0643 pmid:18682516
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Ajlan A,
    2. Achrol AS,
    3. Albakr A, et al
    . Cavernous sinus involvement by pituitary adenomas: clinical implications and outcomes of endoscopic endonasal resection. J Neurol Surg B Skull Base 2017;78:273–82 doi:10.1055/s-0036-1598022 pmid:28603683
    CrossRefPubMed
  20. 20.↵
    1. Woodworth GF,
    2. Patel KS,
    3. Shin B, et al
    . Surgical outcomes using a medial-to-lateral endonasal endoscopic approach to pituitary adenomas invading the cavernous sinus. J Neurosurg 2014;120:1086–94 doi:10.3171/2014.1.JNS131228 pmid:24527820
    CrossRefPubMed
  21. 21.↵
    1. Fahlbusch R,
    2. Honegger J,
    3. Buchfelder M
    . Surgical management of acromegaly. Endocrinol Metab Clin North Am 1992;21:669–92 doi:10.1016/S0889-8529(18)30208-1 pmid:1521518
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Powell M
    . Recovery of vision following transsphenoidal surgery for pituitary adenomas. Br J Neurosurg 1995;9:367–73 doi:10.1080/02688699550041377 pmid:7546358
    CrossRefPubMedWeb of Science
  23. 23.↵
    1. Hisanaga S,
    2. Kakeda S,
    3. Yamamoto J, et al
    . Pituitary macroadenoma and visual impairment: postoperative outcome prediction with contrast-enhanced FIESTA. AJNR Am J Neuroradiol 2017;38:2067–72 doi:10.3174/ajnr.A5394 pmid:28912278
    Abstract/FREE Full Text
  24. 24.↵
    1. Boto J,
    2. Guatta R,
    3. Fitsiori A, et al
    . Is contrast medium really needed for follow-up MRI of untreated intracranial meningiomas? AJNR Am J Neuroradiol 2021;42:1421–28 doi:10.3174/ajnr.A7170 pmid:34117017
    Abstract/FREE Full Text
  25. 25.↵
    1. Buch K,
    2. Juliano A,
    3. Stankovic KM, et al
    . Noncontrast vestibular schwannoma surveillance imaging including an MR cisternographic sequence: is there a need for postcontrast imaging? J Neurosurg 2018;131:549–54 doi:10.3171/2018.3.JNS1866 pmid:30095338
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 43 (7)
American Journal of Neuroradiology
Vol. 43, Issue 7
1 Jul 2022
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Do We Need Gadolinium-Based Contrast Agents for Routine MRI Surveillance of Unoperated Pituitary Macroadenoma?
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
A.A. Alali, P.B. Hanagandi, P.J. Maralani
Do We Need Gadolinium-Based Contrast Agents for Routine MRI Surveillance of Unoperated Pituitary Macroadenoma?
American Journal of Neuroradiology Jul 2022, 43 (7) 1024-1028; DOI: 10.3174/ajnr.A7554

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Need for Gadolinium in Pituitary Macroadenoma MRI
A.A. Alali, P.B. Hanagandi, P.J. Maralani
American Journal of Neuroradiology Jul 2022, 43 (7) 1024-1028; DOI: 10.3174/ajnr.A7554
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Brain Tumor Subtyping Image-Based search via MRI
  • Neuroimaging of Erdheim-Chester Disease
  • CE MRI for Brain Metastasis Detection
Show more Brain Tumor Imaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire