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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Renal Excretion of Contrast on CT Myelography: A Specific Marker of CSF Leak

S. Behbahani, J. Raseman, H. Orlowski, A. Sharma and R. Eldaya
American Journal of Neuroradiology February 2020, 41 (2) 351-356; DOI: https://doi.org/10.3174/ajnr.A6393
S. Behbahani
aFrom the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
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  • ORCID record for S. Behbahani
J. Raseman
aFrom the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
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H. Orlowski
aFrom the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
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A. Sharma
aFrom the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
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R. Eldaya
aFrom the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
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  • FIG 1.
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    FIG 1.

    A 35-year-old man with trauma and MR imaging demonstrating a spinal fluid collection worrisome for CSF leak. Postmyelographic CT (A and B) reveals a ventral epidural fluid collection in the cervical spinal canal with right foraminal extension corresponding to an epidural CSF. A sagittal postmyelographic CT image (C) reveals gross extravasation of contrast into the interspinous space at C7–T1 at the suspected site of a ligamentum flavum injury. Axial images in soft-tissue windows demonstrate contrast in both renal collecting systems in this CTM without visualized intravenous contrast.

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    FIG 2.

    Upper images demonstrate signs of intracranial hypotension on brain MR imaging as demonstrated by cerebellar tonsillar descent through the foramen magnum (A), dilated venous sinuses (B), and diffuse pachymeningeal thickening and enhancement (C). Lower images demonstrate a CT myelogram in the same patient with a subtle CSF-venous fistula in the thoracic spine (arrow) and opacified renal collecting systems.

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    FIG 3.

    Contrast seen in the renal excretory system (renal contrast) in dark gray and total cases in each group in light gray.

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    Table 1:

    Distribution of cases with clinical and/or imaging concern for CSF leak and the control group

    Cases (n = 49)Controls (n = 90)
    Inclusion criteriaClinical suspicion and/or imaging concerning for CSF leakDegenerative changes, spinal canal stenosis, radiculopathy, preoperative planning, and so forth
    Age (yr) (range)19–75 (mean, 49)25–90 (mean, 58)
    SexM = 14, F = 35M = 33, F = 57
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    Table 2:

    Mean Hounsfield unit values of the renal collecting systems for each group

    GroupMean HU in Right Renal PelvisMean HU in Left Renal PelvisMean HU in Renal Pelvisesa
    Control683.21.83
    Clinical- or imaging-suspected CSF leak with no contrast visualized in the renal collecting system2711.713.012
    Suspected CSF leak with contrast visualized in the collecting system7132.8128.5131
    • ↵a The mean for each group was rounded to the next whole number for simplification.

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American Journal of Neuroradiology: 41 (2)
American Journal of Neuroradiology
Vol. 41, Issue 2
1 Feb 2020
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Cite this article
S. Behbahani, J. Raseman, H. Orlowski, A. Sharma, R. Eldaya
Renal Excretion of Contrast on CT Myelography: A Specific Marker of CSF Leak
American Journal of Neuroradiology Feb 2020, 41 (2) 351-356; DOI: 10.3174/ajnr.A6393

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Renal Excretion of Contrast on CT Myelography: A Specific Marker of CSF Leak
S. Behbahani, J. Raseman, H. Orlowski, A. Sharma, R. Eldaya
American Journal of Neuroradiology Feb 2020, 41 (2) 351-356; DOI: 10.3174/ajnr.A6393
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