Metallic Hyperdensity Sign on Noncontrast CT Immediately after Mechanical Thrombectomy Predicts Parenchymal Hemorrhage in Patients with Acute Large-Artery Occlusion

REFERENCES

1. 1.↵
   2. Berkhemer OA,
   3. Fransen PS,
   4. Beumer D, et al

   . A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015;372:11–20 doi:10.1056/NEJMoa1411587 pmid:25517348

   CrossRefPubMedWeb of Science
2. 2.↵
   2. Campbell BC,
   3. Mitchell PJ,
   4. Kleinig TJ, et al

   ; EXTEND-IA Investigators. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 2015;372:1009–18 doi:10.1056/NEJMoa1414792 pmid:25671797

   CrossRefPubMed
3. 3.↵
   2. Goyal M,
   3. Demchuk AM,
   4. Menon BK, et al

   ; ESCAPE Trial Investigators. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 2015;372:1019–30 doi:10.1056/NEJMoa1414905 pmid:25671798

   CrossRefPubMed
4. 4.↵
   2. Jovin TG,
   3. Chamorro A,
   4. Cobo E, et al

   ; REVASCAT Trial Investigators. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 2015;372:2296–306 doi:10.1056/NEJMoa1503780 pmid:25882510

   CrossRefPubMed
5. 5.↵
   2. Saver JL,
   3. Goyal M,
   4. Bonafe A, et al

   ; SWIFT PRIME Investigators. Stent-retriever thrombectomy after intravenous T-PA vs. t-PA alone in stroke. N Engl J Med 2015;372:2285–95 doi:10.1056/NEJMoa1415061 pmid:25882376

   CrossRefPubMed
6. 6.↵
   2. Volny O,
   3. Krajina A,
   4. Belaskova S, et al

   . Mechanical thrombectomy performs similarly in real world practice: a 2016 nationwide study from the Czech Republic. J Neurointerv Surg 2018;10:741–45 doi:10.1136/neurintsurg-2017-013534 pmid:29146830

   Abstract/FREE Full Text
7. 7.↵
   2. Serles W,
   3. Gattringer T,
   4. Mutzenbach S, et al

   ; Austrian Stroke Unit Registry Collaborators. Endovascular stroke therapy in Austria: a nationwide 1-year experience. Eur J Neurol 2016;23:906–11 doi:10.1111/ene.12958 pmid:26843095

   CrossRefPubMed
8. 8.↵
   2. Jiang S,
   3. Fei A,
   4. Peng Y, et al

   . Predictors of outcome and hemorrhage in patients undergoing endovascular therapy with Solitaire stent for acute ischemic stroke. PLoS One 2015;10:e0144452 doi:10.1371/journal.pone.0144452 pmid:26642052

   CrossRefPubMed
9. 9.↵
   2. van Kranendonk KR,
   3. Treurniet KM,
   4. Boers AMM, et al

   ; MR CLEAN investigators. Hemorrhagic transformation is associated with poor functional outcome in patients with acute ischemic stroke due to a large vessel occlusion. J Neurointerv Surg 2018 Oct 8. [Epub ahead of print] doi:10.1136/neurintsurg-2018-014141 pmid:30297537

   CrossRefPubMed
10. 10.↵
    2. Kellert L,
    3. Hametner C,
    4. Rohde S, et al

    . Endovascular stroke therapy: tirofiban is associated with risk of fatal intracerebral hemorrhage and poor outcome. Stroke 2013;44:1453–55 doi:10.1161/STROKEAHA.111.000502 pmid:23463755

    Abstract/FREE Full Text
11. 11.↵
    2. Payabvash S,
    3. Khan AA,
    4. Qureshi MH, et al

    . Detection of intraparenchymal hemorrhage after endovascular therapy in patients with acute ischemic stroke using immediate postprocedural flat-panel computed tomography scan. J Neuroimaging 2016;26:213–18 doi:10.1111/jon.12277 pmid:26282065

    CrossRefPubMed
12. 12.↵
    2. Payabvash S,
    3. Qureshi MH,
    4. Khan SM, et al

    . Differentiating intraparenchymal hemorrhage from contrast extravasation on post-procedural noncontrast CT scan in acute ischemic stroke patients undergoing endovascular treatment. Neuroradiology 2014;56:737–44 doi:10.1007/s00234-014-1381-8 pmid:24925217

    CrossRefPubMed
13. 13.↵
    2. Yoon W,
    3. Seo JJ,
    4. Kim JK, et al

    . Contrast enhancement and contrast extravasation on computed tomography after intra-arterial thrombolysis in patients with acute ischemic stroke. Stroke 2004;35:876–81 doi:10.1161/01.STR.0000120726.69501.74 pmid:14988575

    Abstract/FREE Full Text
14. 14.↵
    2. Jang YM,
    3. Lee DH,
    4. Kim HS, et al

    . The fate of high-density lesions on the non-contrast CT obtained immediately after intra-arterial thrombolysis in ischemic stroke patients. Korean J Radiol 2006;7:221–28 doi:10.3348/kjr.2006.7.4.221 pmid:17143024

    CrossRefPubMedWeb of Science
15. 15.↵
    2. Powers WJ,
    3. Rabinstein AA,
    4. Ackerson T, et al

    ; American Heart Association Stroke Council. 2018 Guidelines for the Early Management of Patients with Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke 2018;49:e46–110 doi:10.1161/STR.0000000000000158 pmid:29367334

    Abstract/FREE Full Text
16. 16.↵
    2. Larrue V,
    3. von Kummer RR,
    4. Müller A, et al

    . Risk factors for severe hemorrhagic transformation in ischemic stroke patients treated with recombinant tissue plasminogen activator: a secondary analysis of the European-Australasian Acute Stroke Study (ECASS II). Stroke 2001;32:438–41 doi:10.1161/01.STR.32.2.438 pmid:11157179

    Abstract/FREE Full Text
17. 17.↵
    2. Lummel N,
    3. Schulte-Altedorneburg G,
    4. Bernau C, et al

    . Hyperattenuated intracerebral lesions after mechanical recanalization in acute stroke. AJNR Am J Neuroradiol 2014;35:345–51 doi:10.3174/ajnr.A3656 pmid:23907245

    Abstract/FREE Full Text
18. 18.↵
    2. Komiyama M,
    3. Nishijima Y,
    4. Nishio A, et al

    . Extravasation of contrast medium from the lenticulostriate artery following local intracarotid fibrinolysis. Surg Neurol 1993;39:315–19 doi:10.1016/0090-3019(93)90013-Q pmid:8488452

    CrossRefPubMed
19. 19.↵
    2. Wildenhain SL,
    3. Jungreis CA,
    4. Barr J, et al

    . CT after intracranial intraarterial thrombolysis for acute stroke. AJNR Am J Neuroradiol 1994;15:487–92 pmid:8197945

    Abstract/FREE Full Text
20. 20.↵
    2. Nakano S,
    3. Iseda T,
    4. Kawano H, et al

    . Parenchymal hyperdensity on computed tomography after intra-arterial reperfusion therapy for acute middle cerebral artery occlusion: incidence and clinical significance. Stroke 2001;32:2042–48 doi:10.1161/hs0901.095602 pmid:11546895

    Abstract/FREE Full Text
21. 21.↵
    2. Parrilla G,
    3. García-Villalba B,
    4. Espinosa de Rueda M, et al

    . Hemorrhage/contrast staining areas after mechanical intra-arterial thrombectomy in acute ischemic stroke: imaging findings and clinical significance. AJNR Am J Neuroradiol 2012;33:1791–96 doi:10.3174/ajnr.A3044 pmid:22538076

    Abstract/FREE Full Text
22. 22.↵
    2. Tomsick T

    . Hyperattenuated intracerebral lesions after mechanical recanalization in acute stroke: contrast and compare. AJNR Am J Neuroradiol 2014;35:352–53 doi:10.3174/ajnr.A3824 pmid:24287093

    FREE Full Text
23. 23.↵
    2. Teng D,
    3. Pannell JS,
    4. Rennert RC, et al

    . Endothelial trauma from mechanical thrombectomy in acute stroke: in vitro live-cell platform with animal validation. Stroke 2015;46:1099–106 doi:10.1161/STROKEAHA.114.007494 pmid:25712942

    Abstract/FREE Full Text
24. 24.↵
    2. Kim JT,
    3. Heo SH,
    4. Cho BH, et al

    . Hyperdensity on non-contrast CT immediately after intra-arterial revascularization. J Neurol 2012;259:936–43 doi:10.1007/s00415-011-6281-9 pmid:22015965

    CrossRefPubMedWeb of Science
25. 25.↵
    2. Burgess RE,
    3. Warach S,
    4. Schaewe TJ, et al

    . Development and validation of a simple conversion model for comparison of intracerebral hemorrhage volumes measured on CT and gradient recalled echo MRI. Stroke 2008;39:2017–20 doi:10.1161/STROKEAHA.107.505719 pmid:18483414

    Abstract/FREE Full Text
26. 26.↵
    2. Liu C,
    3. Shi F,
    4. Chen Z, et al

    . Severe blood-brain barrier disruption in cardioembolic stroke. Front Neurol 2018;9:55 doi:10.3389/fneur.2018.00055 pmid:29472890

    CrossRefPubMed
27. 27.↵
    2. Jickling GC,
    3. Liu D,
    4. Stamova B, et al

    . Hemorrhagic transformation after ischemic stroke in animals and humans. J Cereb Blood Flow Metab 2014;34:185–99 doi:10.1038/jcbfm.2013.203 pmid:24281743

    CrossRefPubMed
28. 28.↵
    2. Dekeyzer S,
    3. Nikoubashman O,
    4. Lutin B, et al

    . Distinction between contrast staining and hemorrhage after endovascular stroke treatment: one CT is not enough. J Neurointerv Surg 2017;9:394–98 doi:10.1136/neurintsurg-2016-012290 pmid:27036980

    Abstract/FREE Full Text