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Research ArticleNeurointervention

The Use and Utility of Aspiration Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis

D. Wei, J.R. Mascitelli, D.A. Nistal, C.P. Kellner, J.T. Fifi, J.D. Mocco and R.A. De Leacy
American Journal of Neuroradiology October 2017, 38 (10) 1978-1983; DOI: https://doi.org/10.3174/ajnr.A5309
D. Wei
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
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J.R. Mascitelli
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
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D.A. Nistal
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
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C.P. Kellner
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
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J.T. Fifi
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
bNeurology (J.T.F.)
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J.D. Mocco
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
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R.A. De Leacy
aFrom the Departments of Neurosurgery (D.W., J.R.M., D.A.N., C.P.K., J.T.F., J.D.M., R.A.D.L.)
cRadiology (R.A.D.L.), Mount Sinai Health System, New York, New York.
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    Fig 1.

    PRISMA flow diagram on study inclusion.

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    Fig 2.

    Forest plot of TICI 2b/3 recanalization rates by study.

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    Forest plot of good outcomes (90-day mRS ≤90) by study.

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    Table 1:

    Treatment times and clinical outcomes by study

    StudyTreatmentNo. of PatientsOTP (min)PTR (min)Final TICI 2b/3 (%)90-Day mRS ≤2 (%)90-Day Mortality (%)Asp Only (%)Asp + Adjuvant (%)
    Mocco et al,13 2016Asp only50227NA70 (30/43)3812NANA
    Park et al,10 2016Asp only322343384783NANA
    Eom et al,7 2014Asp only322817688NA25NANA
    Hwang et al,8 2013Asp only202766365450NANA
    Kang et al,11 2013 (period 1)Asp only61292607449NANANA
    Delgado Almandoz et al,15 2016ADAPT4522450895618NANA
    Hungerford et al,16 2016ADAPT154454409553108119
    Kabbasch et al,18 2016ADAPT30189269043207030
    Kim et al,20 2016ADAPT2523653728408119
    Kowoll et al,21 2016ADAPT541794193NANA5644
    Lapergue et al,22 2016ADAPT124247458253235545
    Mascitelli et al,27 2016ADAPT76295NA92NANA5842
    Romano et al,23 2016ADAPT15222758765186329
    Vargas et al,26 2016ADAPT191468379454157623
    Jankowitz et al,17 2015ADAPT112267708646315941
    Kim et al,9 2015ADAPT702383491603919
    Turk et al,24 2014aADAPT98507379539197822
    Turk et al,25 2014bADAPT64NANA9547NANANA
    Turk et al,12 2014cADAPT373422897NANA7624
    Kang et al,11 2013 (period 2)ADAPT74233688568NANANA
    Kang et al,19 2011ADAPT22318408246148218
    • Note:—Asp indicates aspiration; NA, not available; OTP, onset-to-puncture; PTR, puncture-to-recanalization.

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American Journal of Neuroradiology: 38 (10)
American Journal of Neuroradiology
Vol. 38, Issue 10
1 Oct 2017
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Cite this article
D. Wei, J.R. Mascitelli, D.A. Nistal, C.P. Kellner, J.T. Fifi, J.D. Mocco, R.A. De Leacy
The Use and Utility of Aspiration Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
American Journal of Neuroradiology Oct 2017, 38 (10) 1978-1983; DOI: 10.3174/ajnr.A5309

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The Use and Utility of Aspiration Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
D. Wei, J.R. Mascitelli, D.A. Nistal, C.P. Kellner, J.T. Fifi, J.D. Mocco, R.A. De Leacy
American Journal of Neuroradiology Oct 2017, 38 (10) 1978-1983; DOI: 10.3174/ajnr.A5309
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