Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T

H. Guo; X. Song; R. Vandorpe; Y. Zhang; W. Chen; N. Zhang; M.H. Schmidt; K. Rockwood

doi:10.3174/ajnr.A3709

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Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T

H. Guo, X. Song, R. Vandorpe, Y. Zhang, W. Chen, N. Zhang, M.H. Schmidt and K. Rockwood for the Alzheimer's Disease Neuroimaging Initiative

American Journal of Neuroradiology March 2014, 35 (3) 504-512; DOI: https://doi.org/10.3174/ajnr.A3709

H. Guo

aFrom the Neuroimaging Research Laboratory, Biomedical Translational Imaging Center (H.G., X.S., W.C., N.Z.), QEII & IWK Health Centre (former National Research Council Canada Institute for Biodiagnostics–Atlantic), Halifax, Nova Scotia, Canada

bDepartment of Radiology (G.H., Y.Z., W.C., N.Z.), General Hospital of Tianjin Medical University, Tianjin, China

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X. Song

cDepartments of Medicine (X.S., K.R.)

fCentre for Health Care of the Elderly (X.S., K.R.)

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R. Vandorpe

dRadiology (R.V., M.H.S.)

gDepartment of Diagnostic Imaging (R.V., M.H.S.), QEII Health Sciences Centre, Halifax, Nova Scotia, Canada.

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Y. Zhang

bDepartment of Radiology (G.H., Y.Z., W.C., N.Z.), General Hospital of Tianjin Medical University, Tianjin, China

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W. Chen

bDepartment of Radiology (G.H., Y.Z., W.C., N.Z.), General Hospital of Tianjin Medical University, Tianjin, China

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N. Zhang

bDepartment of Radiology (G.H., Y.Z., W.C., N.Z.), General Hospital of Tianjin Medical University, Tianjin, China

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M.H. Schmidt

dRadiology (R.V., M.H.S.)

gDepartment of Diagnostic Imaging (R.V., M.H.S.), QEII Health Sciences Centre, Halifax, Nova Scotia, Canada.

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K. Rockwood

cDepartments of Medicine (X.S., K.R.)

eNeurology (K.R.), Dalhousie University, Halifax, Nova Scotia, Canada

fCentre for Health Care of the Elderly (X.S., K.R.)

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Online Table 1: Rating schema of the Brain Atrophy and Lesion Index

Online Table 2: T1WI- and T2WI-based Brain Atrophy and Lesion Index total score and subscores at 1.5T and 3T

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H. Guo, X. Song, R. Vandorpe, Y. Zhang, W. Chen, N. Zhang, M.H. Schmidt, K. Rockwood

Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T

American Journal of Neuroradiology Mar 2014, 35 (3) 504-512; DOI: 10.3174/ajnr.A3709

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Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T

H. Guo, X. Song, R. Vandorpe, Y. Zhang, W. Chen, N. Zhang, M.H. Schmidt, K. Rockwood

American Journal of Neuroradiology Mar 2014, 35 (3) 504-512; DOI: 10.3174/ajnr.A3709

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Evaluation of Common Structural Brain Changes in Aging and Alzheimer Disease with the Use of an MRI-Based Brain Atrophy and Lesion Index: A Comparison Between T1WI and T2WI at 1.5T and 3T

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