Abstract
SUMMARY: CTP has a growing role in evaluating stroke. It can be performed immediately following NCCT and has advantages of accessibility and speed. Differentiation of salvageable ischemic penumbra from unsalvageable core infarct may help identify patients most likely to benefit from thrombectomy or thrombolysis. Still, CTP interpretation can be complex. We review normal and ischemic perfusion patterns followed by an illustrative series of technical/diagnostic challenges of CTP interpretation in the setting of acute stroke syndromes.
Abbreviations
- ACA
- anterior cerebral artery
- AIF
- arterial input function
- ASPECTS
- Alberta Stroke Program Early CT Score
- CBF
- cerebral blood flow
- CBV
- cerebral blood volume
- CTA
- CT angiography
- CTP
- CT perfusion
- DWI
- diffusion-weighted imaging
- ICA
- internal carotid artery
- MCA
- middle cerebral artery
- MTT
- mean transit time
- NCCT
- noncontrast CT
- PET
- positron-emission tomography
- SPECT
- single-photon emission CT
- TTP
- time to peak
- VOF
- venous output function
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