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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain

Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study

E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal and H. Zeumer
American Journal of Neuroradiology August 2006, 27 (7) 1426-1431;
E. Goebell
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J. Fiehler
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X.-Q. Ding
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S. Paustenbach
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S. Nietz
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O. Heese
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T. Kucinski
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C. Hagel
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M. Westphal
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H. Zeumer
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    Fig 1.

    A, Regions of interest were placed in the spectroscopic matrix on T2-weighted images (2720/126; 256 × 256 matrix; field of view, 230 × 230 mm; section thickness, 6 mm) in the tumor center (TC), the border of the tumor (TB), the normal-appearing white matter adjacent to the tumor (TNWM), and in the white matter of the contralateral hemisphere (NWMC).

    B, After reslicing and coregristration with the T2-weighted images, the ROIs were transferred to the FA maps (4900/90 ms; 256 × 256 matrix; field of view, 230 × 230 mm; section thickness, 3 mm; b values, 0, 1500 seconds/mm2; EPI factor, 36).

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    Fig 2.

    Median FA values and NAA ratios in the different volumes of interest in the patients.

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    Fig 3.

    Box plot of the N-acetylaspartate/creatine ratios in patients and the control group.

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    Fig 4.

    Box plot of the N-acetylaspartate/choline ratios in patients and the control group.

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    Fig 5.

    Box plot of the FA values in patients and the control group.

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    Fig 6.

    Correlation of median FA values and NAA ratios in the different volumes of interest.

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    Fig 7.

    Distribution of individual FA values of the patients in relation to the corresponding NAA ratios.

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American Journal of Neuroradiology: 27 (7)
American Journal of Neuroradiology
Vol. 27, Issue 7
August 2006
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Cite this article
E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal, H. Zeumer
Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study
American Journal of Neuroradiology Aug 2006, 27 (7) 1426-1431;

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Disarrangement of Fiber Tracts and Decline of Neuronal Density Correlate in Glioma Patients—A Combined Diffusion Tensor Imaging and 1H-MR Spectroscopy Study
E. Goebell, J. Fiehler, X.-Q. Ding, S. Paustenbach, S. Nietz, O. Heese, T. Kucinski, C. Hagel, M. Westphal, H. Zeumer
American Journal of Neuroradiology Aug 2006, 27 (7) 1426-1431;
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