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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Stent-Assisted Angioplasty of Symptomatic Intracranial Vertebrobasilar Artery Stenosis: Feasibility and Follow-up Results

Dong Joon Kim, Byung Hee Lee, Dong Ik Kim, Won Heum Shim, Pyoung Jeon and Tae Hong Lee
American Journal of Neuroradiology June 2005, 26 (6) 1381-1388;
Dong Joon Kim
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Byung Hee Lee
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Dong Ik Kim
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Won Heum Shim
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Pyoung Jeon
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Tae Hong Lee
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    Fig 1.

    Representative case of multistaged balloon inflation technique in a patient with left distal vertebral artery stenosis.

    A, Pretreament angiogram shows a severely stenosed left distal vertebral artery at the site of posterior inferior cerebellar artery.

    B, Angiogram shows the stent placed at the targeted lesion site; slow subnominal inflation (5 atm in this case) of the balloon was performed, with special consideration given to preventing “dog boning” of the proximal and distal ends of the balloon. Angiogram (not shown) was obtained to confirm the absence of a gap at the distal end of the stent.

    C, Angiogram shows the balloon is carefully retrieved, with the proximal balloon marker (dotted arrow) placed outside the struts of the proximal end of the stent (solid arrow).

    D, The balloon was slowly inflated to or above the nominal pressure, with special consideration given to avoiding any gap in the middle and proximal aspects of the stents. Repeat inflations were performed if any gap was visualized on the angiogram.

    E, Final angiogram shows a well-positioned stent without gaps.

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    Fig 2.

    Case 8. A 55-year-old man with transient ischemic attack at presentation.

    A, Initial left vertebral artery angiogram shows 95% stenosis of the intracranial vertebral artery.

    B, Angiogram shows that the distal vertebral artery is straightened because of the stent-mounted catheter, and the lesion site is displaced more cranially (arrow). Primary stent deployment was attempted with a S660 2.5/9 stent; however, the distal end of the stent could not pass through the lesion site. Stent catheter was not retrieved because of concerns for acute thrombus formation. Notice the compromised flow in the basilar artery due to the trapped stent catheter.

    C, Magnified angiographic view. After deployment of the initial stent (solid arrows) and additional careful angioplasty, a second stent-mounted catheter (dotted arrows) was navigated through the initial stent.

    D, Magnified angiographic view. The second stent (dotted arrows) was deployed partially overlapping the initial stent (solid arrows) and covering the distal aspect of the lesion.

    E, Final angiogram shows no residual stenosis.

    F, Seventeen-month follow-up angiogram shows the patent stent site without significant restenosis.

Tables

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    TABLE 1:

    Summary of patient characteristics and treatment

    Case No.SexAgeLesion LocationComorbiditiesMori Lesion TypeStenosis (%)Predilatation (mm)Stent (mm)Complication
    BeforeAfter
    1F58BAHB590Maxxum 2.75/12S660 2.75/18Acute in-stent thrombosis*
    2F63BAH, D, LA655Jo flex 4/16
    IVA, LtC600S670 3/24
    3F65IVA, LtHB6210S670 3.5/18
    4M60BAHC820Maverick 2/12Cypher 2.5/13Dizziness, ataxia†
    5M51IVA, RtH, D, SC950Maestro 1.5/20Jo flex 2.5/23
    6M70IVA, LtH, D, S, CA900S670 4/18
    7F66IVA, LtH, DB700Jo flex 4/23
    8M55IVA, LtH, D, L, S, CA950S660 2.5/9, 2.5/12‡
    9M70IVA, RtH, CC700Jo bare 5/17
    10M74IVA, RtH, D, S, MB690Ranger 2.5/20AVE 3.5/12
    11F60BAHC950S670 3/18
    12M69BAHB900Jo flex 3.5/16
    13M62IVA, LtH, LB740Larus 2.5/10Jo Stent 3.0/12
    14F65BAHC905S670 3.5/24
    IVA, LtB600S670 4/24
    15F76IVA, LtH, D, L, SC800S660 2.5/15,S670 3/19§
    16M68IVA, LtH, S, CC505S7 4/30
    17M60IVA, LtH, L, SC900Maestro 1.5/20Jo flex 3/19
    • Note.—IVA indicates intracranial vertebral artery; BA, basilar artery; H, hypertension; D, diabetes mellitus; L, hyperlipidemia; S, smoking; C, coronary artery disease.

    • * Recanalized after intraarterial abciximab injection.

    • † Improved during hospitalization.

    • ‡ First stent was trapped by the tight stenosis and had to be deployed proximal to the lesion site; thus, a second stent was used for distal angioplasty.

    • § Two stents used for long length of the lesion.

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    TABLE 2:

    Clinical and angiographic follow-up results

    Case No.Clinical Follow-upAngiographic Follow-up
    Duration (mo)Clinical OutcomeDuration (mo)Restenosis (%)
    110Improved, residual dizziness0.50
    212Improved, unrelated TIA at 3 mo30*
    311Improved60
    410Improved, residual dizziness614
    513Improved610
    612Improved120
    718Improved, unrelated TIA at 15 mo150
    823Improved, unrelated minor stroke at 19 mo175
    920Improved170
    1045Improved, residual dizziness250
    1141Improved4110
    126Improved
    137Improved
    1441Improved
    157Improved
    1610Improved, thalamic ICH at 2 mo
    176Improved
    • Note.—TIA indicates transient ischemic attack; ICH, intracranial hemorrhage.

    • * Includes both verterbral artery and basilar artery lesions.

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American Journal of Neuroradiology: 26 (6)
American Journal of Neuroradiology
Vol. 26, Issue 6
1 Jun 2005
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Cite this article
Dong Joon Kim, Byung Hee Lee, Dong Ik Kim, Won Heum Shim, Pyoung Jeon, Tae Hong Lee
Stent-Assisted Angioplasty of Symptomatic Intracranial Vertebrobasilar Artery Stenosis: Feasibility and Follow-up Results
American Journal of Neuroradiology Jun 2005, 26 (6) 1381-1388;

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Stent-Assisted Angioplasty of Symptomatic Intracranial Vertebrobasilar Artery Stenosis: Feasibility and Follow-up Results
Dong Joon Kim, Byung Hee Lee, Dong Ik Kim, Won Heum Shim, Pyoung Jeon, Tae Hong Lee
American Journal of Neuroradiology Jun 2005, 26 (6) 1381-1388;
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Cited By...

  • Percutaneous transluminal angioplasty and stenting (PTAS) in patients with symptomatic intracranial vertebrobasilar artery stenosis (IVBS)
  • Stenting for intracranial stenosis: potential future for the prevention of disabling or fatal stroke
  • Stroke recurrence rates among patients with symptomatic intracranial vertebrobasilar stenoses: systematic review and meta-analysis
  • Symptom Differences and Pretreatment Asymptomatic Interval Affect Outcomes of Stenting for Intracranial Atherosclerotic Disease
  • Higher Risk of Recurrent Ischemic Events in Patients With Intracranial In-Stent Restenosis
  • Standard of practice: endovascular treatment of intracranial atherosclerosis
  • Guidelines for the Prevention of Stroke in Patients With Stroke or Transient Ischemic Attack: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
  • Reporting standards for angioplasty and stent-assisted angioplasty for intracranial atherosclerosis
  • Long term clinical and angiographic outcomes with the Wingspan stent for treatment of symptomatic 50-99% intracranial atherosclerosis: single center experience in 51 cases
  • Risk factors associated with major cerebrovascular complications after intracranial stenting
  • Reporting Standards for Angioplasty and Stent-Assisted Angioplasty for Intracranial Atherosclerosis
  • A Systematic Review on Outcome After Stenting for Intracranial Atherosclerosis
  • The NIH registry on use of the Wingspan stent for symptomatic70-99% intracranial arterial stenosis
  • Apollo Stent for Symptomatic Atherosclerotic Intracranial Stenosis: Study Results
  • Comparison of elective stenting of severe vs moderate intracranial atherosclerotic stenosis
  • Perforator stroke after elective stenting of symptomatic intracranial stenosis
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