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Research ArticleBRAIN TUMOR IMAGING

Image-Based Search in Radiology: Identification of Brain Tumor Subtypes within Databases Using MRI-Based Radiomic Features

Marc von Reppert, Saahil Chadha, Klara Willms, Arman Avesta, Nazanin Maleki, Tal Zeevi, Jan Lost, Niklas Tillmanns, Leon Jekel, Sara Merkaj, MingDe Lin, Karl-Titus Hoffmann, Sanjay Aneja, Mariam S. Aboian and for the IBSR Consortium
American Journal of Neuroradiology June 2025, DOI: https://doi.org/10.3174/ajnr.A8805
Marc von Reppert
aFrom the University of Leipzig (M.v.R., K.W., K.-T.H., S.A.), Leipzig, Germany
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  • ORCID record for Marc von Reppert
Saahil Chadha
bDepartment of Radiology and Biomedical Imaging (S.C., A.A.), Yale School of Medicine, New Haven, Connecticut
cCenter for Outcomes Research and Evaluation (S.C.), Yale School of Medicine, New Haven, Connecticut
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Klara Willms
aFrom the University of Leipzig (M.v.R., K.W., K.-T.H., S.A.), Leipzig, Germany
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Arman Avesta
bDepartment of Radiology and Biomedical Imaging (S.C., A.A.), Yale School of Medicine, New Haven, Connecticut
dDepartment of Radiology (A.A.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
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Nazanin Maleki
eDepartment of Radiology (N.M., M.S.A.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Tal Zeevi
fCenter for Translational Imaging Analysis and Machine Learning, Department of Radiology and Biomedical Imaging (T.Z.), Yale School of Medicine, New Haven, Connecticut
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Jan Lost
gDepartment of Neurosurgery (J.L.), Heinrich-Heine-University, Duesseldorf, Germany
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Niklas Tillmanns
hDepartment of Diagnostic and Interventional Radiology, Medical Faculty (N.T.), University Dusseldorf, Dusseldorf, Germany
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Leon Jekel
iUniversity of Duisburg-Essen (L.J.), Essen, Germany
jDKFZ Division of Translational Neuro-oncology at the WTZ, German Cancer Consortium, DKTK Partner Site (L.J.), University Hospital Essen, Essen, Germany
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Sara Merkaj
kUniversity of Ulm (S.M.), Ulm, Germany
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MingDe Lin
lVisage Imaging, Inc. (M.L.), San Diego, California
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Karl-Titus Hoffmann
aFrom the University of Leipzig (M.v.R., K.W., K.-T.H., S.A.), Leipzig, Germany
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Sanjay Aneja
aFrom the University of Leipzig (M.v.R., K.W., K.-T.H., S.A.), Leipzig, Germany
mDepartment of Therapeutic Radiology (S.A.), Yale School of Medicine, New Haven, Connecticut
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Mariam S. Aboian
eDepartment of Radiology (N.M., M.S.A.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
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Article Information

DOI 
https://doi.org/10.3174/ajnr.A8805
PubMed 
40250848

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received August 2, 2024
  • Accepted after revision December 11, 2024
  • Published online June 20, 2025.

Article Versions

  • Latest version (April 18, 2025 - 10:54).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2025 by American Journal of Neuroradiology

Author Information

  1. Marc von Repperta,
  2. Saahil Chadhab,c,
  3. Klara Willmsa,
  4. Arman Avestab,d,
  5. Nazanin Malekie,
  6. Tal Zeevif,
  7. Jan Lostg,
  8. Niklas Tillmannsh,
  9. Leon Jekeli,j,
  10. Sara Merkajk,
  11. MingDe Linl,
  12. Karl-Titus Hoffmanna,
  13. Sanjay Anejaa,m,
  14. Mariam S. Aboiane,
  15. for the IBSR Consortium
  1. aFrom the University of Leipzig (M.v.R., K.W., K.-T.H., S.A.), Leipzig, Germany
  2. bDepartment of Radiology and Biomedical Imaging (S.C., A.A.), Yale School of Medicine, New Haven, Connecticut
  3. cCenter for Outcomes Research and Evaluation (S.C.), Yale School of Medicine, New Haven, Connecticut
  4. dDepartment of Radiology (A.A.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  5. eDepartment of Radiology (N.M., M.S.A.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  6. fCenter for Translational Imaging Analysis and Machine Learning, Department of Radiology and Biomedical Imaging (T.Z.), Yale School of Medicine, New Haven, Connecticut
  7. gDepartment of Neurosurgery (J.L.), Heinrich-Heine-University, Duesseldorf, Germany
  8. hDepartment of Diagnostic and Interventional Radiology, Medical Faculty (N.T.), University Dusseldorf, Dusseldorf, Germany
  9. iUniversity of Duisburg-Essen (L.J.), Essen, Germany
  10. jDKFZ Division of Translational Neuro-oncology at the WTZ, German Cancer Consortium, DKTK Partner Site (L.J.), University Hospital Essen, Essen, Germany
  11. kUniversity of Ulm (S.M.), Ulm, Germany
  12. lVisage Imaging, Inc. (M.L.), San Diego, California
  13. mDepartment of Therapeutic Radiology (S.A.), Yale School of Medicine, New Haven, Connecticut
      1. Please address correspondence to Mariam S. Aboian, Department of Radiology, Children’s Hospital of Philadelphia, 3500 Civic Center Blvd, Philadelphia, PA 19104; e-mail: aboianm{at}chop.edu; @MariamAboian
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      Funding

      • National Center for Advancing Translational Sciences

        KL2 TR00186 grant

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      Cite this article
      Marc von Reppert, Saahil Chadha, Klara Willms, Arman Avesta, Nazanin Maleki, Tal Zeevi, Jan Lost, Niklas Tillmanns, Leon Jekel, Sara Merkaj, MingDe Lin, Karl-Titus Hoffmann, Sanjay Aneja, Mariam S. Aboian, for the IBSR Consortium
      Image-Based Search in Radiology: Identification of Brain Tumor Subtypes within Databases Using MRI-Based Radiomic Features
      American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8805

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      Brain Tumor Subtyping Image-Based search via MRI
      Marc von Reppert, Saahil Chadha, Klara Willms, Arman Avesta, Nazanin Maleki, Tal Zeevi, Jan Lost, Niklas Tillmanns, Leon Jekel, Sara Merkaj, MingDe Lin, Karl-Titus Hoffmann, Sanjay Aneja, Mariam S. Aboian, for the IBSR Consortium
      American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8805
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