Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Getting new auth cookie, if you see this message a lot, tell someone!
Research ArticlePEDIATRIC NEUROIMAGING

Frontal Paraventricular Cysts: Refined Definitions and Outcomes

Matthew T. Whitehead, Amirreza Manteghinejad, César A.P.F. Alves, Onur Simsek, Nahla Khalek and Erin S. Schwartz
American Journal of Neuroradiology June 2025, DOI: https://doi.org/10.3174/ajnr.A8653
Matthew T. Whitehead
aFrom the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bPerelmann School of Medicine (M.T.W., N.K., E.S.S.), University of Pennsylvania, Philadelphia, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Matthew T. Whitehead
Amirreza Manteghinejad
aFrom the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Amirreza Manteghinejad
César A.P.F. Alves
aFrom the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
cDivision of Neuroradiology, Department of Radiology (C.A.P.F.A), Boston Children’s Hospital, Boston, Massachusetts
dHarvard Medical School (C.A.P.F.A), Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for César A.P.F. Alves
Onur Simsek
aFrom the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Onur Simsek
Nahla Khalek
bPerelmann School of Medicine (M.T.W., N.K., E.S.S.), University of Pennsylvania, Philadelphia, Pennsylvania
eDepartment of Obstetrics and Gynecology (N.K.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erin S. Schwartz
aFrom the Division of Neuroradiology, Department of Radiology (M.T.W., A.M., C.A.P.F.A., O.S, E.S.S.), Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
bPerelmann School of Medicine (M.T.W., N.K., E.S.S.), University of Pennsylvania, Philadelphia, Pennsylvania
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Erin S. Schwartz
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Tan ZYJ,
    2. Naidoo P,
    3. Kenning N
    . Case of the month. Ultrasound and MRI features of connatal cysts: clinicoradiological differentiation from other supratentorial periventricular cystic lesions. Br J Radiology 2010;83:180–83 doi:10.1259/bjr/10458905 pmid:20139266
    FREE Full Text
  2. 2.↵
    1. Sun C,
    2. Zhang X,
    3. Chen X, et al
    . Evaluation of MRI features and neurodevelopmental outcomes for prenatally diagnosed periventricular pseudocysts. Front Pediatr 2021;9:681999 doi:10.3389/fped.2021.681999 pmid:34746043
    CrossRefPubMed
  3. 3.↵
    1. Pal BR,
    2. Preston PR,
    3. Morgan ME, et al
    . Frontal horn thin walled cysts in preterm neonates are benign. Arch Dis Child Fetal Neonatal Ed 2001;85:F187–93 doi:10.1136/fn.85.3.f187 pmid:11668161
    Abstract/FREE Full Text
  4. 4.↵
    1. Scelsi CL,
    2. Rahim TA,
    3. Morris JA, et al
    . The lateral ventricles: a detailed review of anatomy, development, and anatomic variations. AJNR Am J Neuroradiol 2020;41:566–72 doi:10.3174/ajnr.A6456 pmid:32079598
    Abstract/FREE Full Text
  5. 5.↵
    1. Chang C-L,
    2. Chiu N-C,
    3. Ho C-S, et al
    . Frontal horn cysts in normal neonates. Brain Dev 2006;28:426–30 doi:10.1016/j.braindev.2006.01.002 pmid:16503391
    CrossRefPubMed
  6. 6.↵
    1. De León GA,
    2. Girling DJ
    . Cystic degeneration of the telencephalic subependymal germinal layer in newborn infants. J Neurol Neurosurg Psychiatry 1975;38:265–71 doi:10.1136/jnnp.38.3.265 pmid:1151407
    Abstract/FREE Full Text
  7. 7.↵
    1. Sener RN
    . MRI and asymptomatic coarctation of the frontal lateral ventricle horn. J Neuroradiol 1997;24:163–67 pmid:9297937
    PubMed
  8. 8.↵
    1. Sun LR,
    2. Tekes A,
    3. Golden WC, et al
    . Connatal cyst in a preterm twin infant with maternal comorbidities. Pediatr Neurol 2014;51:444–47 doi:10.1016/j.pediatrneurol.2014.05.030 pmid:25023976
    CrossRefPubMed
  9. 9.↵
    1. Lin Y-J,
    2. Chiu N-C,
    3. Chen H-J, et al
    . Cranial ultrasonographic screening findings among healthy neonates and their association with neurodevelopmental outcomes. Pediatr Neonatol 2021;62:158–64 doi:10.1016/j.pedneo.2020.10.012 pmid:33214065
    CrossRefPubMed
  10. 10.↵
    1. Bates JI,
    2. Netsky MG
    . Developmental anomalies of the horns of the lateral ventricles. J Neuropathol Exp Neurol 1955;14:316–25 doi:10.1097/00005072-195507000-00009
    CrossRefPubMed
  11. 11.↵
    1. Davidoff LM
    . Coarctation of the walls of the lateral angles of the lateral cerebral ventricles. J Neurosurg 1946;3:250–56 doi:10.3171/jns.1946.3.3.0250
    CrossRefPubMed
  12. 12.↵
    1. Epelman M,
    2. Daneman A,
    3. Blaser SI, et al
    . Differential diagnosis of intracranial cystic lesions at head US: correlation with CT and MR imaging. Radiographics 2006;26:173–96 doi:10.1148/rg.261055033 pmid:16418251
    CrossRefPubMed
  13. 13.↵
    1. Larroche JC
    . Sub-ependymal pseudo-cysts in the newborn. Biol Neonate 1972;21:170–83 doi:10.1159/000240506 pmid:4656184
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Bats AS,
    2. Molho M,
    3. Senat MV, et al
    . Subependymal pseudocysts in the fetal brain: prenatal diagnosis of two cases and review of the literature. Ultrasound Obstet Gynecol 2002;20:502–05 doi:10.1046/j.1469-0705.2002.00848.x pmid:12423490
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Ramenghi LA,
    2. Domizio S,
    3. Quartulli L, et al
    . Prenatal pseudocysts of the germinal matrix in preterm infants. J Clin Ultrasound 1997;25:169–73 doi:10.1002/(SICI)1097-0096(199705)25:4<169::AID-JCU3>3.0.CO;2-C
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Viñals F,
    2. Correa F,
    3. Tubau A, et al
    . New insights into the anterior complex. Fetal Diagn Ther 2020;47:514–18 doi:10.1159/000504980 pmid:31931505
    CrossRefPubMed
  17. 17.↵
    1. Cooper S,
    2. Bar-Yosef O,
    3. Berkenstadt M, et al
    . Prenatal evaluation, imaging features, and neurodevelopmental outcome of prenatally diagnosed periventricular pseudocysts. AJNR Am J Neuroradiol 2016;37:2382–88 doi:10.3174/ajnr.A4916 pmid:27609618
    Abstract/FREE Full Text
  18. 18.↵
    1. Trawber R,
    2. Rao S,
    3. Srinivasjois R, et al
    . Outcomes of preterm neonates with frontal horn cysts: a retrospective study. J Child Neurol 2010;25:1377–81 doi:10.1177/0883073810366600 pmid:20448250
    CrossRefPubMed
  19. 19.↵
    1. Cevey-Macherel M,
    2. Forcada Guex M,
    3. Bickle Graz M, et al
    . Neurodevelopment outcome of newborns with cerebral subependymal pseudocysts at 18 and 46 months: a prospective study. Arch Dis Child 2013;98:497–502 doi:10.1136/archdischild-2012-303223 pmid:23625989
    Abstract/FREE Full Text
  20. 20.↵
    1. Levy M,
    2. Lev D,
    3. Leibovitz Z, et al
    . Periventricular pseudocysts of noninfectious origin: prenatal associated findings and prognostic factors. Prenat Diagn 2020;40:931–41 doi:10.1002/pd.5704 pmid:32277778
    CrossRefPubMed
  21. 21.↵
    1. Lu JH,
    2. Emons D,
    3. Kowalewski S
    . Connatal periventricular pseudocysts in the neonate. Pediatr Radiology 1992;22:55–58 doi:10.1007/BF02011609 pmid:1594311
    CrossRefPubMed
  22. 22.↵
    1. Bosemani T,
    2. Huisman TAGM,
    3. Poretti A
    . Benign frontal horn cysts in a preterm neonate. J Perinatol 2014;34:488 doi:10.1038/jp.2013.187 pmid:24872125
    CrossRefPubMed
  23. 23.↵
    1. Malinger G,
    2. Lev D,
    3. Ben Sira L, et al
    . Congenital periventricular pseudocysts: prenatal sonographic appearance and clinical implications. Ultrasound Obstet Gynecol 2002;20:447–51 doi:10.1046/j.1469-0705.2002.00840.x pmid:12423480
    CrossRefPubMed
  24. 24.↵
    1. van Wezel-Meijler G,
    2. van der Knaap MS,
    3. Sie LT, et al
    . Magnetic resonance imaging of the brain in premature infants during the neonatal period. Normal phenomena and reflection of mild ultrasound abnormalities. Neuropediatrics 1998;29:89–96 doi:10.1055/s-2007-973541 pmid:9638663
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Esteban H,
    2. Blondiaux E,
    3. Audureau E, et al
    . Prenatal features of isolated subependymal pseudocysts associated with adverse pregnancy outcome. Ultrasound Obstet Gynecol 2015;46:678–87 doi:10.1002/uog.14820 pmid:25684100
    CrossRefPubMed
  26. 26.↵
    1. Rademaker KJ,
    2. De Vries LS,
    3. Barth PG
    . Subependymal pseudocysts: ultrasound diagnosis and findings at follow-up. Acta Paediatr 1993;82:394–99 doi:10.1111/j.1651-2227.1993.tb12705.x pmid:8318809
    CrossRefPubMedWeb of Science
  27. 27.↵
    1. Saini N,
    2. Vijayasree V,
    3. Nandury EC, et al
    . Prenatal phenotype of FBXL4-associated encephalomyopathic mitochondrial DNA depletion syndrome-13. Prenat Diagn 2022;42:1682–85 pmid:36411461
    CrossRefPubMed
  28. 28.↵
    1. Gilani A,
    2. Hove JLV,
    3. Thomas JA, et al
    . Distinguishing encephaloclastic lesions resulting from primary or secondary pyruvate dehydrogenase deficiency from other neonatal or infantile cavitary brain lesions. Pediatr Dev Pathol 2020;23:189–96 doi:10.1177/1093526619876448 pmid:31542992
    CrossRefPubMed
  29. 29.↵
    1. Loeffen J,
    2. Smeets R,
    3. Voit T, et al
    . Fumarase deficiency presenting with periventricular cysts. J Inherit Metab Dis 2005;28:799–800 doi:10.1007/s10545-005-0044-7 pmid:16151915
    CrossRefPubMed
  30. 30.↵
    1. Leijser LM,
    2. de Vries LS,
    3. Rutherford MA, et al
    . Cranial ultrasound in metabolic disorders presenting in the neonatal period: characteristic features and comparison with MR imaging. AJNR Am J Neuroradiol 2007;28:1223–31 doi:10.3174/ajnr.A0553 pmid:17698520
    CrossRefPubMed
  31. 31.↵
    1. Kwee RM,
    2. Kwee TC
    . Virchow-Robin spaces at MR imaging. Radiographics 2007;27:1071–86 doi:10.1148/rg.274065722 pmid:17620468
    CrossRefPubMedWeb of Science
  32. 32.↵
    1. Guibaud L,
    2. Attia-Sobol J,
    3. Buenerd A, et al
    . Focal sonographic periventricular pattern associated with mild ventriculomegaly in foetal cytomegalic infection revealing cytomegalic encephalitis in the third trimester of pregnancy. Prenat Diagn 2004;24:727–32 doi:10.1002/pd.914 pmid:15386462
    CrossRefPubMed
  33. 33.↵
    1. Roee B,
    2. Adi W,
    3. Michael B, et al
    . Subtle findings on fetal brain imaging in CMV infected pregnancies: what is the clinical significance? A retrospective analysis with outcome correlation. Prenat Diagn 2020;40:447–53 doi:10.1002/pd.5634 pmid:31875430
    CrossRefPubMed
  34. 34.↵
    1. Lucignani G,
    2. Guarnera A,
    3. Rossi-Espagnet MC, et al
    . From fetal to neonatal neuroimaging in TORCH infections: a pictorial review. Children (Basel) 2022;9:1210 doi:10.3390/children9081210 pmid:36010101
    CrossRefPubMed
PreviousNext
Back to top
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Frontal Paraventricular Cysts: Refined Definitions and Outcomes
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Matthew T. Whitehead, Amirreza Manteghinejad, César A.P.F. Alves, Onur Simsek, Nahla Khalek, Erin S. Schwartz
Frontal Paraventricular Cysts: Refined Definitions and Outcomes
American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8653

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Frontal Paraventricular Cysts
Matthew T. Whitehead, Amirreza Manteghinejad, César A.P.F. Alves, Onur Simsek, Nahla Khalek, Erin S. Schwartz
American Journal of Neuroradiology Jun 2025, DOI: 10.3174/ajnr.A8653
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Sodium MRI in Pediatric Brain Tumors
  • FRACTURE MR in Congenital Vertebral Anomalies
Show more Pediatric Neuroimaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire