Article Figures & Data
Figures
- FIG 1.
Distribution of the final mTICI according to BGC versus non-BGC use.
- FIG 2.
Distribution of mRS at 3 months according to BGC versus non-BGC use.
Tables
Overall Patients ≥80 Years (n = 808) Non-BGC Use (n = 343, 42.5%) BGC Use (n = 465, 57.5%) P Value Age (median) (IQR) (yr) 85 (83–88) 85 (82–88) 86 (83–89) .001 Female sex (No.) (%) 521 (64.5) 217 (63.3) 304 (65.4) .535 NIHSS score at admission (median) (IQR) 17 (12–21) 18 (13–21) 16 (11–21) .035 ASPECTS at admission (median) (IQR) 9 (7–10) 8 (7–10) 9 (8–10) .008 Time from stroke onset to diagnosis (median) (IQR) (min) 280 (180.75–589.25) 300 (196.5–564) 261 (172–609) .069 IV tPA administered (No.) (%) 212 (26.2) 114 (33.2) 98 (21.1) <.001 General anesthesia during EVT (No.) (%) 262 (32.4) 120 (35) 142 (30.5) .142 Right-sided occlusion (No.) (%) 388 (48) 157 (45.8) 231 (49.7) .272 Level of vessel occlusion (No.) (%) .002 Carotid terminus 157 (19.5) 79 (23) 78 (16.8) MCA-M1 425 (52.7) 189 (55.1) 236 (50.9) MCA-M2 225 (27.9) 75 (21.9) 150 (32.3) GPTFR (median) (IQR) (min) 7 (5–12) 9 (5–16) 6 (4–10) <.001 ET time (median) (IQR) (min) 25 (12–43) 30 (16–49) 22 (11–39) <.001 GTR (median) (IQR) (min) 35 (22–57) 42 (27–66.5) 30 (19–49.25) <.001 SR use 790 (97.8) 335 (97.7) 455 (97.8) .863 Distal aspiration catheter use (No.) (%) 422 (52.2) 406 (51.4) 16 (88.9) .002 Combined technique use (CA + SR) 406 (50.2) 292 (85.1) 114 (24.5) <.001 FPE (mTICI 3) (No.) (%) 293 (36.3) 112 (32.7) 181 (38.9) .067 mFPE (mTICI 2c–3) (No.) (%) 350 (43.3) 137 (39.9) 213 (45.8) .096 FPE (mTICI 2b–3) (No.) (%) 435 (53.8) 175 (51) 260 (55.9) .168 Final No. of passes (No.) (%) .991 1 380 (47) 161 (46.9) 219 (47.1) 2 192 (23.8) 81 (23.6) 111 (23.9) >2 236 (29.2) 101 (29.4) 135 (29) Technique modification 134 (27.9) 75 (35.4) 59 (21.9) .001 mTICI 0 after first pass 256 (31.7) 118 (34.4) 138 (29.7) .154 Final mTICI 0 29 (3.6) 17 (5) 12 (2.6) .073 Final mTICI ≥ 2b (No.) (%) 744 (92.1) 308 (89.8) 436 (93.8) .039 Final mTICI ≥ 2c (No.) (%) 587 (72.6) 227 (66.2) 360 (77.4) <.001 Emboli to new territory 129 (16) 59 (17.2) 70 (15.1) .410 sICH (No.) (%) 53 (6.6) 36 (10.5) 17 (3.7) <.001 Complications .692 Perforation 11 (29.7) 5 (29.4) 6 (30) Dissection 15 (40.5) 8 (47.1) 7 (35) NIHSS score at 24 hr (median) (IQR) 8 (3–16) 10.5 (4–17) 7 (2–15) .002 Early neurologic deterioration (No.) (%) 52 (6.4) 26 (7.5) 26 (5.6) .071 mRS 0-1 at 3 mo 191 (23.6) 81 (23.6) 110 (23.7) .989 mRS 0-2 at 3 mo 303 (37.5) 136 (39.7) 167 (35.9) .278 Mortality at 3 mo (No.) (%) 225 (27.8) 107 (31.2) 118 (25.4) .068 Note:—IQR indicates interquartile range; SR, stent retriever; CA, contact aspiration.
Overall Patients ≥80 Years (n = 808) No mFPE (n = 458, 56.7%) mFPE (n = 350, 43.3%) P Value Age (median) (IQR) (yr) 85 (83–88) 85 (83–88) 85 (83–88.75) .294 Female sex (No.) (%) 521 (64.5) 293 (56.2) 228 (43.8) .731 NIHSS score at admission (median) (IQR) 17 (12–21) 17 (12–21) 17 (12–20) .323 ASPECTS at admission (median) (IQR) 9 (7–10) 9 (7–10) 9 (8–10) .002 Last time seen well (median) (IQR) (min) 280 (180.75–589.25) 280 (183–608) 280 (178–568.5) .478 IV tPA administered (No.) (%) 212 (26.2) 125 (27.3) 87 (24.9) .459 General anesthesia (No.) (%) 262 (32.4) 138 (30.1) 124 (35.4) .123 Local anesthesia (No.) (%) 160 (19.8) 87 (19) 73 (20.9) Conscious sedation (No.) (%) 386 (47.8) 233 (50.9) 153 (43.7) Right-sided occlusion (No.) (%) 388 (48) 226 (49.3) 162 (46.3) .388 Level of vessel occlusion (No.) (%) .564 Carotid terminus 157 (19.5) 94 (20.6) 63 (18) MCA-M1 425 (52.7) 234 (51.2) 191 (54.6) MCA-M2 225 (27.9) 129 (28.2) 96 (27.4) GPTFR (median) (IQR) (min) 7 (5–12) 7 (5–13) 7 (5–12) .202 ET time (median) (IQR) (min) 25 (12–43) 37 (25–54.5) 12 (8–20) <.001 GTR (median) (IQR) (min) 35 (22–57) 48 (35–71) 22 (15–31) <.001 BGC use (No.) (%) 465 (57.5) 252 (55) 213 (60.9) .096 SR (No.) (%) 790 (97.8) 446 (97.4) 344 (98.3) .387 Combined technique use (CA + SR) 406 (50.2) 241 (52.6) 165 (47.1) .123 Distal aspiration catheter use (No.) (%) 422 (52.2) 251 (54.8) 171 (48.9) .094 Technique modification 134 (27.9) 130 (31.1) 4 (6.3) <.001 sICH (No.) (%) 53 (6.6) 37 (8.1) 16 (4.6) .134 Complications .548 Perforation 11 (29.7) 10 (33.3) 1 (14.3) Dissection 15 (40.5) 12 (40) 3 (42.9) NIHSS score at 24 hr (median) (IQR) 8 (3–16) 12 (5–18) 5 (2–12) <.001 mRS score 0–2 at 3 mo (No.) (%) 303 (37.5) 146 (31.9) 157 (44.9) <.001 Mortality at 3 mo (No.) (%) 225 (27.8) 154 (33.6) 71 (20.3) <.001 Note:—SR indicates stent retriever; CA, contact aspiration.
Variable P Value aOR 95% CI Model 1: mFPE (mTICI 2c–3)a AUC = 0.845 BGC use .459 0.851 0.556–1.303 Distal aspiration catheter use .333 1.230 0.809–1.872 ASPECTS .102 0.981 0.981–1.236 Model 2: final mTICI 2c–3b AUC = 0.765 BGC use .772 0.938 0.607–1.449 Distal aspiration catheter use .013 0.570 0.366–0.888 SR use .004 1.225 1.282–1.619 GTR <.001 0.979 0.974–0.984 ASPECTS .004 1.190 1.057–1.340 NIHSS admission .549 .991 0.961–1.022 IV tPA administered .014 .494 0.281–0.869 Right-sided occlusion .020 0.652 0.456–0.934 Note:—BGC indicates balloon guide catheter and distal aspiration catheter use; aOR, adjusted OR; SR, stent retriever.
↵a Variables included in model 1 with a P value < .1 in the univariate analysis for FPE (mTICI2c–3).
↵b Variables included in model 2 with P value < .1 in the univariate analysis for final mTICI 2c–3.
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