Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurointervention

Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy

G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler and J.J. Heit
American Journal of Neuroradiology May 2023, DOI: https://doi.org/10.3174/ajnr.A7879
G. Adusumilli
aFrom the Department of Radiology (G.A.), Massachusetts General Hospital, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for G. Adusumilli
T.D. Faizy
bDepartment of Neuroradiology (T.D.F., J.F.), University of Hamburg-Eppendorf, Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T.D. Faizy
S. Christensen
cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Mlynash
cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Mlynash
Y. Loh
eComprehensive Stroke Center (Y.L.), Swedish Neuroscience Institute, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G.W. Albers
cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.G. Lansberg
cStanford Stroke Center (S.C., M.M., G.W.A., M.G.L.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.G. Lansberg
J. Fiehler
bDepartment of Neuroradiology (T.D.F., J.F.), University of Hamburg-Eppendorf, Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Fiehler
J.J. Heit
dDepartment of Radiology (J.J.H.), Stanford University, Stanford, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J.J. Heit
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • FIG 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 1.

    Degrees of internal cerebral vein opacification. From left to right, zero opacification of the ICV, moderate opacification of the ICV, and full opacification of the ICV.

  • FIG 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 2.

    Patient screening and inclusion flowchart.

  • FIG 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 3.

    mRS score (A) and TICI score (B) distribution of patients with CVO+ versus CVO–. Within each mRS or TICI score category, the percentage of patients with that score is noted.

Tables

  • Figures
    • View popup
    Table 1:

    Demographic profile of patients by VO status

    CVO+(n = 315)CVO–(n = 363)P Value
    Age (median) (IQR) (yr)73 (62–81)77 (67–85)<.001
    Female (No.) (%)145 (46%)209 (58%).003
    Atrial fibrillation (No.) (%) (n = 311, 361)115 (37%)148 (41%).287
    Hypertension (No.) (%) (n = 313, 361)203 (65%)261 (72%).037
    Blood glucose level (median) (IQR) (mg/dL) (n = 272, 309)117 (103–144)123 (106–154).028
    Diabetes (No.) (%) (n = 313, 360)53 (17%)78 (22%).122
    Hyperlipidemia (No.) (%) (n = 276, 317)82 (30%)93 (29%).921
    Smoker (current/prior) (No.) (%) (n = 292, 342)85 (29%)79 (23%).085
    NIHSS score on presentation (median) (IQR)11 (7–17)17 (12–20)<.001
    tPA administration (No.) (%) (n = 311, 355)189 (61%)148 (42%)<.001
    • View popup
    Table 2:

    Imaging metrics at baseline and follow-up by VO status

    CVO+(n = 315)CVO−(n = 363)P Value
    ASPECTS (median) (IQR)8 (7–10)7 (6–9)<.001
    Baseline infarct volume (median) (IQR) (n = 309, 359)5 (0–17.5)18 (3–48)<.001
    Follow-up infarct volume (median) (IQR) (n = 304, 343)12.4 (4.8–34.2)54.3 (22.1–120.3)<.001
    Change in infarct volume (median) (IQR) (n = 298, 340)+5.9 (−0.4–22.1)+32.1 (4.1–82.7)<.001
PreviousNext
Back to top
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler, J.J. Heit
Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy
American Journal of Neuroradiology May 2023, DOI: 10.3174/ajnr.A7879

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy
G. Adusumilli, T.D. Faizy, S. Christensen, M. Mlynash, Y. Loh, G.W. Albers, M.G. Lansberg, J. Fiehler, J.J. Heit
American Journal of Neuroradiology May 2023, DOI: 10.3174/ajnr.A7879
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • Prolonged venous transit on perfusion imaging is associated with higher odds of mortality in successfully reperfused patients with large vessel occlusion stroke
  • Poor venous outflow is associated with hyperintense acute reperfusion marker on follow-up MRI in patients with acute ischemic stroke with a large vessel occlusion
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Rescue Reentry in Carotid Near-Occlusion
  • Contour Neurovascular System: Five Year Follow Up
  • Effect of SARS-CoV2 on Endovascular Thrombectomy
Show more Neurointervention

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire