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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Major Radiologic and Clinical Outcomes of Total Spine MRI Performed in the Emergency Department at a Major Academic Medical Center

C.W.C. Huang, A. Ali, Y.-M. Chang, A.F. Bezuidenhout, D.B. Hackney, J.A. Edlow and R.A. Bhadelia
American Journal of Neuroradiology May 2020, DOI: https://doi.org/10.3174/ajnr.A6578
C.W.C. Huang
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
cDepartment of Radiology (C.W.C.H.), Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
dDepartment of Radiology (C.W.C.H.), School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
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  • ORCID record for C.W.C. Huang
A. Ali
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
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Y.-M. Chang
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
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A.F. Bezuidenhout
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
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D.B. Hackney
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
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J.A. Edlow
bEmergency Medicine (J.A.E.), Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts
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R.A. Bhadelia
aFrom the Departments of Radiology (C.W.C.H., A.A., Y.-M.C., A.F.B., D.B.H., R.A.B.)
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  • FIG 1.
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    FIG 1.

    A 67-year-old woman with a history of breast cancer presented with bilateral lower extremity and right upper extremity weakness. The upper portion of total spine MR imaging with T2-weighted sagittal (A) and axial (B) images shows severe compression of the spinal cord at the T4 level with no CSF visualized within the spinal canal at that level.

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    FIG 2.

    An 83-year-old man presenting with lower back pain, leg numbness, leg weakness, and urinary retention. T2-weighted sagittal (A) and axial (B) images from total spine MR imaging show a herniated L4–L5 intervertebral disc causing severe spinal canal stenosis with a lack of CSF within the thecal sac, suggesting cauda equina compression.

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    FIG 3.

    A 41-year-old man with a history of intravenous drug use presenting with fever, severe diffuse back pain, and right lower quadrant abdominal pain. The lower portion of total spine MR imaging with T1-weighted postcontrast sagittal (A) and axial (B) images shows discitis and osteomyelitis, with epidural and right paraspinal phlegmon.

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    Table 1:

    Radiologic and clinical outcomes of TS-MR imaginga

    Radiologic Outcomes of TS-MR Imaging with Major Radiologic Outcome(N = 321) 117/321 (36.4%)Major Clinical Outcome in Patients, (n = 60/321) (18.6%)
    During Visit 58/117 (49.6%)b<24 Hours 33/117 (28.2%)c
    SCC or CEC723620
     Degenerative disease41123
     Neoplasm16125
     Infection101010
     Hematoma222
     Iatrogenic100
     Traumatic findings200
    Other significant findings452213
     Neoplasm1981
     Infection888
     Iatrogenic111
     Spinal cord lesion733
     Traumatic findings300
     Extraspinal findingsd720
    Without major radiologic outcome204/321 (63.6%)2/204 (1.0%)b1/204 (0.5%)c
    • Note:—Bold indicates total of subsequent raws respectively.

    • ↵a Clinical Outcome: hospital admission followed by an operation, radiation, IV therapy (antibiotics or steroids), or abscess drainage during same visit as well as in <24 hours and >24 hours after arrival to ED.

    • ↵b Odds Ratio = 99 (95% CI, 23.5–419; P value < .001) between patients with and without major radiologic outcomes.

    • ↵c Odds Ratio = 80 (95% CI, 10.7–593; P value < .001) between patients with and without major radiologic outcomes.

    • ↵d Psoas muscle abscess and lymphoma.

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    Table 2:

    Impact of HRCP and neurologic findings on major clinical outcomesa

    VariableNo. of Patients (N = 321)During VisitOdds Ratio (95% CI)P Value<24 HoursOdds Ratio (95% CI)P Value
    HRCP + NF142/321 (44%)40/142 (28%)3.1 (1.7–5.6)<.00122/142 (15%)2.6 (1.2–5.4).01
    HRCP or NF alone179/321 (56%)20/179 (11%)12/179 (7%)
    • Note:—NF indicates neurologic findings.

    • ↵a Major clinical outcomes of patients who had both HRCP + NF were compared with patients who had either HRCP or NF alone.

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C.W.C. Huang, A. Ali, Y.-M. Chang, A.F. Bezuidenhout, D.B. Hackney, J.A. Edlow, R.A. Bhadelia
Major Radiologic and Clinical Outcomes of Total Spine MRI Performed in the Emergency Department at a Major Academic Medical Center
American Journal of Neuroradiology May 2020, DOI: 10.3174/ajnr.A6578

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Major Radiologic and Clinical Outcomes of Total Spine MRI Performed in the Emergency Department at a Major Academic Medical Center
C.W.C. Huang, A. Ali, Y.-M. Chang, A.F. Bezuidenhout, D.B. Hackney, J.A. Edlow, R.A. Bhadelia
American Journal of Neuroradiology May 2020, DOI: 10.3174/ajnr.A6578
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