Tumor Response Assessment in Diffuse Intrinsic Pontine Glioma: Comparison of Semiautomated Volumetric, Semiautomated Linear, and Manual Linear Tumor Measurement Strategies

^aFrom the Departments of Radiology (L.A.G., J.L.L.)
^bCancer and Blood Diseases Institute (M.D.D.-S., M.F.), Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
^cDepartment of Graduate Medical Education (L.A.G., M.D.D.-S.), Mount Carmel Health System, Columbus, Ohio
^dDepartments of Pediatrics (M.F., P.D.)
^eRadiology (J.L.L.), University of Cincinnati College of Medicine, Cincinnati, Ohio.

Please address correspondence to James L. Leach, MD, Department of Radiology, MLC 5031, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229; e-mail: james.leach{at}cchmc.org

Funding

This work was financially supported in part by Novartis Pharmaceuticals. A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy. ClinicalTrials.gov Identifier: NCT02607124
Additional support: The Cure Starts Now Foundation, Hope for Caroline Foundation, Julian Boivin Courage for Cures Foundation, Abbie's Army, Michael Mosier Defeat DIPG Foundation, Reflections of Grace Foundation, The Cure Starts Now Australia, Brooke Healey Foundation, Soar With Grace Foundation, Jeffrey Thomas Hayden Foundation, Cure Brain Cancer Foundation, The Jones Family Foundation, Musella Foundation, Pray, Hope Believe Foundation, Smiles for Sophie Foundation, Benny's World, Love Chloe Fou