Nonmicrocephalic Infants with Congenital Zika Syndrome Suspected Only after Neuroimaging Evaluation Compared with Those with Microcephaly at Birth and Postnatally: How Large Is the Zika Virus “Iceberg”?

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.

From the Centro Diagnostico Multimagem (M.F.V.V.A.), Recife, Brazil; Federal University of Pernambuco (A.C.H.), Recife, Brazil; Pronto-Socorro Cardiológico de Pernambuco (Procape) (A.M.B.-L., M.M.V.), University of Pernambuco, Recife, Brazil; Barão de Lucena Hospital (N.C.L.P.), Recife, Brazil; Department of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina; Association for Assistance of Disabled Children (V.v.d.L.), Recife, Brazil; Clínica de Apoio Ocupacional (S.C.S.), Jaboatío dos Guararapes, Brazil; Dom Malan Hospital (A.G.T.), Petrolina, Brazil; Laboratório Fernando Travassos (P.T.C.T.), Recife, Brazil; Centro de Pesquisas Aggeu Magalhãaes (M.T.C., C.S.), Fiocruz, Recife, Brazil; and Department of Maternal, Child, and Adolescent Health (A.C.), World Health Organization, Geneva, Switzerland.