Brain Structural and Vascular Anatomy Is Altered in Offspring of Pre-Eclamptic Pregnancies: A Pilot Study

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.

From the Department of Biomedical and Molecular Sciences (M.T.R., A.F.H., B.M., V.R.K., S.M., G.N.S., J.N.R., B.A.C.) and Centre for Neuroscience Studies (A.P., D.B., P.W.S., M.A.A., J.N.R.), Queen's University, Kingston, Ontario, Canada; Department of Obstetrics and Gynecology (J.P., G.N.S.), Kingston General Hospital, Kingston, Ontario, Canada; and Department of Radiology and Hotchkiss Brain Institute (N.D.F.), University of Calgary, Calgary, Alberta, Canada.