Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
Sign up to receive an email alert when a new Case of the Week is posted.
November 8, 2010 (Main)
Progressive Supranuclear Palsy
- Progressive supranuclear palsy (PSP) is a rare neurodegenerative disease characterized by dementia, supranuclear ophthalmoplegia, and postural instability.
- Patients usually present after the first 4 decades of life.
- Key Diagnostic Features: Mid-brain atrophy is the characteristic imaging finding, best appreciated on MR imaging. Sagittal T1WI or T2WI demonstrate loss of volume of the superior colliculus. Concavity of the lateral margin of the tegmentum has also been described.
- DDx: Corticobasal degeneration, Parkinson's disease.
Current Issue
Case Collections
