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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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October 6, 2016
  • Description
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Terson Syndrome

  • Background:
    • Terson syndrome was described in 1900 by Alfres Terson, a French ophthalmologist.
    • It corresponds to a subhyloid hemorrhage with involvement of the vitreous in the setting of acute aneurysmal subarachnoid hemorrhage.
    • It is thought to be due to a rapid increase in ICP.
    • Depending on the diagnostic method and the definition used, the incidence varies from 8-46%.
    • It is more commonly seen in ruptured ACommA aneurysms.
    • The diagnosis of Terson syndrome is clinically important, as it is associated with significantly higher mortality1.
    • Up to 77% of these cases are overlooked on daily reports2.
  • Key Diagnostic Features:
    • Findings can be quite subtle and may vary between slight retinal thickening to nodularity or crescent-shaped, increased density on the retinal surface.
  • Differential Diagnoses:
    • In the setting of acute SAH, a crescentic-shaped hyper density of the posterior globe is in keeping with Terson syndrome3.
    • Beware of false positive CT findings, commonly due to volume averaging, at the rectus muscle insertions. True findings are most reliably seen adjacent to the optic nerve.
  • Treatment:
    • This condition often requires timely ophthalmologic intervention to prevent long term visual loss.
    • The current patient had a re-bleed while undergoing emergency coiling of the anterior communicating artery aneurysm and died within 48 hours of presentation.

Suggested Reading

  1. Stienen MN, Lücke S, Gautschi OP, Harders A. Terson haemorrhage in patients suffering aneurysmal subarachnoid haemorrhage: A prospective analysis of 60 consecutive patients. Clin Neurol Neurosurg 2012;114:535-38, 10.1016/j.clineuro.2011.10.034
  2. McCarron MO, Alberts MJ, McCarron P. A systematic review of Terson's syndrome: frequency and prognosis after subarachnoid haemorrhage. J Neurol Neurosurg Psychiatry 2004;75:491-93, 10.1136/jnnp.2003.016816
  3. Swallow CE, Tsuruda JS, Digre KB, Glaser MJ, Davidson HC, Harnsberger HR. Terson syndrome: CT evaluation in 12 patients. AJNR Am J Neuroradiol 1998;19:743-47

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American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
Vol. 46, Issue 6
1 Jun 2025
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