Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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April 22, 2013
Benign Lymphoepithelial Cysts
- Benign lymphoepithelial lesions (cystic and solid) are seen in approximately 5% of HIV positive patients.
- On pathology these are seen as cystic lesions lined by squamous epithelium accompanied with abundant lymphoid stroma. Rarely, these lesions may transform into B-cell lymphoma.
- Bilateral painless swelling of the neck in the parotid regions. Age: any age group in patients infected with HIV
- Key Diagnostic Features: Multiple cystic and solid lesions in both parotid glands. Associated findings such as reactive cervical adenopathy and hypertrophy of lymphoid tissue in the palatine, lingual, or adenoid regions may be seen.
- DDx: Sjögren's syndrome, sarcoidosis, Warthin's tumor, lymphoma and metastasis
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