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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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April 16, 2015
  • Description
  • Legends
  • Legends 2
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Giant Tonsillolith Migration, Secondary Perforation, and an Associated Mediastinitis

  • Palatine tonsillolithiasis is a benign condition characterized by calcific foci in the tonsils that result from chronic bacterial infection in the tonsillar crypts.
  • In a recent study, the prevalence of asymptomatic tonsilloliths in 150 consecutive CT scans requested for reasons other than tonsillolithiasis was 24.6%, with no lesions exceeding 7 mm. Diagnosis of giant tonsilloliths has been reported in sporadic case presentations.
  • Tonsillolithiasis is asymptomatic. However, in cases of giant tonsilloliths, patients may complain of foreign body sensation, odynophagia or earache.
  • We are not aware of previous reports describing a tonsillolithiasis related life-threatening complication similar to the current case.
  • Descending cervical mediastinitis (DCM) is a rare but extremely severe disease caused by dissemination of a cervicofacial infection to the mediastinum along the fascial layers (retropharyngeal and danger spaces).
  • Rx: Surgical removal. Therapy of DCM is based on surgical drainage and debridement combined with intravenous broad-spectrum antibiotics and supportive care.

Suggested Reading

Kanotra S(ohil), Kanotra S(onika), Paul J. A giant tonsillolith. Indian J Ophthalmol 2008;60:277–80, 10.1007/s12070-008-0093-y

Fauroux MA, Mas C, Tramini P, et al. Prevalence of palatine tonsilloliths: a retrospective study on 150 consecutive CT examinations. Dentomaxillofac Radiol 2013;42:7, 10.1259/dmfr.20120429

Scaglione M, Pinto A, Giovine S, et al. CT features of descending necrotizing mediastinitis—a pictorial essay. Emerg Radiol 2007;14:77–81, 10.1007/s10140-007-0606-0

Current Issue

American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
Vol. 46, Issue 6
1 Jun 2025
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