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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Week

Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada

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Submit a Case Previous Cases ASPNR Pediatric Cases

March 28, 2011
  • Description
  • Legends
  • Diagnosis
  • Brain Teaser
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Psammomatoid Ossifying Fibroma

  • Ossifying fibromas are benign fibro-osseus tumors, typically seen in the third decade of life.
  • Most commonly found in the craniofacial bones; involvement of the mandible is not uncommon.
  • Symptoms vary depending on tumor location. Nasal obstruction, rhinorrhea, epistaxis, and pain are commonly encountered symptoms. Rarely, facial disfigurement can be seen.
  • Key Diagnostic Features: Well-defined heterogenous density mass lesion demonstrating areas of osseous matrix interspersed with areas of ground-glass opacification, and low attenuation containing fibrous tissue or retained mucus are seen. Lesional circumscription, prevalence of osteoblastic rimming around the bone trabeculae, and variability in tissue composition within the lesion can be considered to be diagnostic imaging features of this disease entity.
  • DDx: Fibrous dysplasia, Osteoma, Osteogenic sarcoma
  • Treatment: Surgical resection

Suggested Reading

Han MH, Chang KH, Lee CH, et al. Sinonasal psammomatoid ossifying fibromas: CT and MR manifestations. AJNR Am J Neuroradiol 1991;12:25-30.

Vandekerckhove K, Van den Abeele K, Van den Broecke C, et al. Psammomatoid ossifying fibroma of the ethmoid. Bull Soc Belge Ophtalmol 2003;287:9-14.

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American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
Vol. 46, Issue 6
1 Jun 2025
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Print ISSN: 0195-6108 Online ISSN: 1936-959X

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