Case of the Week
Section Editors: Matylda Machnowska1 and Anvita Pauranik2
1University of Toronto, Toronto, Ontario, Canada
2BC Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada
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January 3, 2011
Primary Intraosseous Meningioma
- Primary intraosseous meningiomas are rare tumors, accounting for 1% of all meningiomas.
- These tumors likely arise from dura and arachnoid cap cells entrapped in the sutures during develoment, after trauma or from multipotent mesenchymal cells.
- They are classified as purely extracalvarial (type I), purely calvarial (type II), or calvarial with extracalvarial extension (type III).
- Types include purely osteolytic, mixed osteolytic-osteoblastic, and purely osteoblastic.
- Key Diagnostic Features: Enlargement of the diploic space is seen. The lesion itself can appear osteolytic, mixed lytic-blastic or purely osteoblastic.
- DDx: Predominantly lytic lesion: metastasis, eosinophilic granuloma, epidermoid cyst, fibrous dysplasia, and multiple myeloma; Predominantly osteoblastic lesion: metastasis, osteoma, hyperparathyroidism
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