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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Case of the Month

Section Editor: Nicholas Stence, MD
Children's Hospital Colorado, Aurora, CO

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August 2015
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Next Case of the Month coming September 1 . . .

Mandibular Arteriovenous Malformation

  • A high-flow subtype of head and neck vascular malformations
  • Rare and potentially life-threatening1
  • Often present with minor gingival bleeding, tooth loosening, lip numbness, malocclusion, and sometimes massive arterialized hemorrhage after dental procedures. Hemorrhagic shock following extraction of teeth.2
  • Cross-sectional imaging can demonstrate findings ranging from small periapical lucencies to large, well-circumscribed erosive lesions. Bony overgrowth can occur.
  • Postcontrast imaging demonstrates enhancement in areas of erosion similar to surrounding vessels
  • Dynamic postcontrast MRA can diagnose arteriovenous shunting for treatment planning prior to embolization
  • Color Doppler US may be used to document arterialized flow
  • Multiple approaches to therapy have been used successfully, including transarterial, transvenous, or percutaneous embolization, and in some cases, resection with reconstruction of the mandible3–7
  • Differential includes lytic mandibular tumors and slow-flow venous malformations. As a biopsy of this lesion would carry obvious significant hemorrhagic risk, careful attention to the density/intensity of contrast enhancement relative to nearby vessels, detection of nearby enlarged abnormal vessels, and performance of dynamic angiography to document A-V shunting are crucial for appropriate management.

Suggested Reading

  1. Lamberg MA, Tasanen A, Jääskeläinen J. Fatality from central hemangioma of the mandible. J Oral Surg 1979;37:578–84
  2. Mohammadi H, Said-Al-Naief NAH, Heffez LB. Arteriovenous malformation of the mandible. Oral Surg Oral Med Oral Pathol Oral Radiol 1997;84:286–89, 10.1016/S1079-2104(97)90344-9
  3. Lungren MP, Patel MN. Endovascular management of head and neck vascular malformations. Curr Otorhinolaryngol Rep 2014;2:273–84, 10.1007/s40136-014-0053-x
  4. Chandra RV, Leslie-Mazwi TM, Orbach DB, et al. Transarterial embolization of mandibular arteriovenous malformations using ONYX. J Oral Maxillofac Surg 2014;72:1504–10, 10.1016/j.joms.2014.02.025
  5. Koshy CG, Keshava SN, Moses V, et al. Case report: combined transarterial and direct approaches for embolization of a large mandibular arteriovenous malformation. Indian J Radiol Imag 2011;21:6–9, 10.4103/0971-3026.76044
  6. Churojana A, Khumtong R, Songsaeng D, et al. Life-threatening arteriovenous malformation of the maxillomandibular region and treatment outcomes. Interv Radiol 2012;18:49–59, 10.1177/159101991201800107
  7. Lemound J, Brachvogel P, Götz, et al. Treatment of mandibular high-flow vascular malformations: report of 2 cases. J Oral Maxillofac Surg 2011;69:1956–66, 10.1016/j.joms.2010.09.013

Current Issue

American Journal of Neuroradiology: 46 (6)
American Journal of Neuroradiology
Vol. 46, Issue 6
1 Jun 2025
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