Graphical Abstract
Abstract
SUMMARY: Physician-industry financial relationships can drive research and innovation, improving patient care and outcomes, but also potentially raise ethical concerns if not disclosed appropriately. This study shows high rates of nondisclosures by authors/presenters at the American Society of Neuroradiology 2024 annual meeting, despite strict requirements. A total of 86.4% of presenters/authors with records in the open payments database failed to disclose any financial relationship, and 89.9% of total industry payment value was not disclosed. Greater awareness should help improve disclosures and transparency, reducing the risk and perception of bias.
ABBREVIATIONS:
- ASNR
- American Society of Neuroradiology
- IQR
- interquartile range
- OPD
- open payments database
Financial relationships between industry and physicians are common, with up to 70% of radiologists having received at least 1 industry payment in the past 5 years.1⇓⇓-4 Industry payments for activities like research and consulting help promote research and medical innovation, and a recent study showed the proportion of industry payments in radiology in categories reflecting innovation (royalty/ownership and research fees) is second only to surgical specialties.5 However, transparent disclosure of industry relationships is critical to avoid potential conflicts of interest. Recent studies have shown high rates of nondisclosures by authors in radiology journals despite the financial relationships being common.6⇓-8 National society meetings like the American Society of Neuroradiology (ASNR) annual meeting are avenues for dissemination of knowledge including medical breakthroughs, and are widely attended. The aim of this study is to assess the disclosure rates of industry financial relationships by presenters at the ASNR national meeting.
MATERIALS AND METHODS
Selection of Presenters
The online archive of 21 scientific sessions at ASNR 2024, Las Vegas, Nevada, in May 2024 was accessed via the virtual attendee platform.9 Full name and affiliations of presenters and coauthors of scientific presentations in each session was collected by using an HTML scraping script. Self-reported financial disclosures were collected from the ASNR 2024 disclosure index, accessed via the virtual attendee platform.
Selection of Industry Payments
The selected authors/presenters were then searched in the open payments database (OPD) for exact matches of first name, last name, and state. Those with more than 1 name match were resolved individually by comparing the exact address of the affiliated institution. Using the OPD data sets for program year 2021 to 2023, industry payments made within the previous 24 months (ie, since May 2022) were recorded for each author found in the OPD.
Payment Characteristics
Payments are categorized as general, research, or ownership interest, according to the OPD. General payments are payments made that are not in connection with a research agreement or research protocol, and have subcategories including consulting fees, faculty or speaker compensation, honoraria, gifts, entertainment, food-and-beverage, travel and lodging, education, charitable contributions, royalty or licenses, long-term medical supply or device loans, space rental or facility fees, and acquisitions.
We further classified each payment as disclosed or undisclosed based on the authors’ self-reported conflict of interest disclosure statement. An industry relationship was defined as the name of the company (manufacturer or Group Purchasing Organization [GPO]) that made payments to the author within the inclusion period, and authors were classified based on the completeness of disclosed relationships: those who disclosed all industry relationships, those who disclosed some, and those who disclosed none of the OPD-reported industry relationships.
Statistical Analysis
Payment amounts in each category were reported as median, 25th and 75th percentile values, due to the skewed distribution of payment amounts. The proportion of amount undisclosed and prevalence of nondisclosure was reported by using descriptive statistics. The OPD data were analyzed by using Python v3.10 modules: Pandas and NumPy, and the ASNR 2024 online meeting archive were scraped by using Beautiful Soup v4.4.
Results
ASNR 2024 Presenters
A total of 1222 authorships, including 886 unique authors, were included from 190 scientific presentations at ASNR 2024. From the OPD, 162 authors/presenters were found by name and affiliation, and 68% (110/162) of presenters received industry payments within the previous 24 months.
Total sum of payments to the 110 unique authors amounted to $2,954,303, and median payment per author was $1-420 (interquartile range [IQR] = $171–$13,291; range = $13–$433,499) (Fig 1). Research and associated research category payments amounted to $1,201,639 to 22 authors (median = $35,517; IQR = $16,004–$99,018), and general category payments amounted to $1,224,018 to 107 authors (median = $744; IQR = $164–$4,657). Ownership interest to 3 authors amounted to $528,647 (Table).
Amount of payments in general and research category. Boxes extend from the first quartile (Q1) to the third quartile (Q3) of the data. The whiskers extend from the box to the farthest data point lying within 1.5× the IQR from the box. Outliers beyond this range are not shown.
Disclosed and undisclosed industry payments by category
Financial relationships from the OPD were compared against the authors’ self-reported COI disclosure statement. Out of the 110 authors who received industry payments, 2 authors self-reported all industry payments and 13 authors self-reported some of the industry payments. The remaining 95 (86.4%) authors failed to disclose any financial relationship. After stratifying the authors by total amount received, those who received between $10 000–$100 000 had the lowest nondisclosure rate of 61% (11/18 authors failed to disclose any financial relationship), which amounted to 71% of the payments being undisclosed (Fig 2).
Disclosure rate by authors (A) and by amount (B). x-axis represents the range of total amount received, stratified on a logarithmic scale (<1000, 1000–10,000, 10,000–100,000, and >100,000). USD = US dollars.
Total amount of undisclosed payments was $2,656,390 (89.9% of total), and median undisclosed amount per author was $772 (IQR = $157-$8,139).
The industry partners making the payments to the ASNR presenters and payments in each category are provided in the Supplemental Data.
DISCUSSION
Our study results show high nondisclosure rates by presenters at the annual national meeting of ASNR. Sixty-eight percent (110/162 unique presenters with records in OPD) received at least 1 industry payment. Forty-one percent ($1,201,639/$2,954,303) of the absolute value of payments was in the research and associated research categories, to 22 of 110 individuals. Eighty-three percent of general payments and 92% of research payments were undisclosed. Similar to previous studies, the industry payments are highly concentrated while the median payment in the general category is relatively small ($744; IQR = $164–$4,657).1,2,10
There are multiple possible reasons for the high nondisclosure rate. There seems to be lack of awareness of reporting requirements. For 2023, any payment over $12.69 had to be reported, and if the amount was lower, it needed to be disclosed if the aggregate amount exceeded 10 times that amount ($126.89) in the calendar year.11 A commonly cited reason for nondisclosure is that physicians may deem the financial relationship as not relevant to the subject matter of the presentation.12 However, the ASNR policy on disclosures is nonambiguous; “ASNR must be able to show that individuals in a position to control the content of an education activity, including committee members, reviewers, planners, authors, and presenters, have disclosed to ASNR all financial relationships with ineligible companies in the previous 24 months. Individuals in a position to control the content must disclose all relationships, regardless of their view of the relevance of the relationship(s) to the education.” The ACCME defines ineligible companies as “those whose primary business is producing, marketing, selling, re-selling, or distributing health care products used by or on patients.” As the study results show (Supplemental Data), most of the industry payments were made from manufacturers of imaging equipment, contrast media, device manufacturers, and pharmaceutical companies.
In 2010, the US Congress passed the Physician Payments Sunshine Act as part of the Affordable Care Act to help increase transparency of industry-physician relationships. Industry payment data are collected and published by the Centers for Medicare & Medicaid Services and are publicly available in the OPD.13 The OPD site reflects the most recent 7 years of OPD data.14 The data for each calendar year are updated on the website in June end of the subsequent year. Covered recipients have a 45-day prepublication review and dispute period (April 1 to May 15) to ensure the data are accurate before releasing it to the public.15
There are several limitations to by using the OPD database. The data include information on US-based authors only. Considering that ASNR gets speakers/presenters from all around the world, the number of physicians receiving industry payments may be underreported here. The database relies on accurate reporting from the industry. Physicians are supposed to cross-check and dispute any entries that are being reported by the industry. However, there is a general lack of awareness. In the senior author’s personal experience, erroneous reporting by industry to OPD can go unchallenged unless disputed in the prescribed 45-day period. Challenging it subsequently is a difficult and time-consuming process.
This study focused on payments made to physicians and does not capture payments made to organizations or academic institutions. The proportion of authors receiving payments in this study may also be under-reported since trainees may be listed as presenters/authors and payments to trainees are excluded from the OPD database.
In conclusion, greater awareness and transparency on disclosures of financial conflicts-of-interest are needed. It would reduce the risk of bias, and increase the public’s trust in the science being presented.
Footnotes
Disclosure forms provided by the authors are available with the full text and PDF of this article at www.ajnr.org.
References
- Received September 23, 2024.
- Accepted after revision October 24, 2024.
- © 2025 by American Journal of Neuroradiology