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This multisite study found that the consensus DSC-MRI acquisition protocol confirmed the utility of standardized rCBV (srCBV) to identify biologically active, treatment-naïve brain metastases as distinguished from normal-appearing white matter and GBM. The data demonstrated that brain metastases of different primary origins have srCBV values that in general are significantly greater than normal-appearing white matter but significantly lower than srCBV for GBM.

This clinical report identified the spectrum of MRI characteristics and pathologic patterns of myxopapillary ependymomas. Histopathologic analysis identified a microcystic pattern in larger tumors and a solid pattern in the 4 smaller tumors. The findings suggest a possible association between cases with drop metastases and cases of large tumors with a microcystic pattern.