Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleNeurovascular

Efficacy Assessment of Cerebral Perfusion Augmentation through Functional Connectivity in an Acute Canine Stroke Model

Chisondi S. Warioba, Mira Liu, Sagada Peñano, Timothy J. Carroll, Sean Foxley and Gregory Christoforidis
American Journal of Neuroradiology September 2024, 45 (9) 1214-1219; DOI: https://doi.org/10.3174/ajnr.A8320
Chisondi S. Warioba
aFrom the Department of Radiology (C.S.W., M.L., S.P., T.J.C., S.F.), University of Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Chisondi S. Warioba
Mira Liu
aFrom the Department of Radiology (C.S.W., M.L., S.P., T.J.C., S.F.), University of Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Mira Liu
Sagada Peñano
aFrom the Department of Radiology (C.S.W., M.L., S.P., T.J.C., S.F.), University of Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Timothy J. Carroll
aFrom the Department of Radiology (C.S.W., M.L., S.P., T.J.C., S.F.), University of Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Timothy J. Carroll
Sean Foxley
aFrom the Department of Radiology (C.S.W., M.L., S.P., T.J.C., S.F.), University of Chicago, Chicago, Illinois
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gregory Christoforidis
bMount Carmel Health (G.C.), Columbus, Ohio.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gregory Christoforidis
  • Article
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Tsao CW,
    2. Aday AW,
    3. Almarzooq ZI, et al
    . Heart disease and stroke statistics—2022 update: a report from the American Heart Association. Circulation 2022;145:e18–209 doi:10.1161/CIR.0000000000001052 pmid:35078371
    CrossRefPubMed
  2. 2.↵
    1. Powers WJ,
    2. Rabinstein AA,
    3. Ackerson T, et al
    . Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2019;50:e344–418 doi:10.1161/STR.0000000000000211 pmid:31662037
    CrossRefPubMed
  3. 3.↵
    1. Alia C,
    2. Spalletti C,
    3. Lai S, et al
    . Neuroplastic changes following brain ischemia and their contribution to stroke recovery: novel approaches in neurorehabilitation. Front Cell Neurosci 2017;11:76 doi:10.3389/fncel.2017.00076 pmid:28360842
    CrossRefPubMed
  4. 4.↵
    1. Tuladhar AM,
    2. Snaphaan L,
    3. Shumskaya E, et al
    . Default mode network connectivity in stroke patients. PLoS ONE 2013;8:e66556 doi:10.1371/journal.pone.0066556 pmid:23824302
    CrossRefPubMed
  5. 5.↵
    1. He BJ,
    2. Snyder AZ,
    3. Zempel JM, et al
    . Electrophysiological correlates of the brain's intrinsic large-scale functional architecture. Proc Natl Acad Sci U S A 2019;116:183–92
  6. 6.↵
    1. Ogawa S,
    2. Lee TM,
    3. Kay AR, et al
    . Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci U S A 1990;87:9868–72 doi:10.1073/pnas.87.24.9868 pmid:2124706
    Abstract/FREE Full Text
  7. 7.↵
    1. Smitha KA,
    2. Akhil Raja K,
    3. Arun KM, et al
    . Resting state fMRI: A review on methods in resting state connectivity analysis and resting state networks. Neuroradiol J 2017;30:305–17 doi:10.1177/1971400917697342 pmid:28353416
    CrossRefPubMed
  8. 8.↵
    1. Fox MD,
    2. Raichle ME
    . Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 2007;8:700–11 doi:10.1038/nrn2201 pmid:17704812
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. Jeong YI,
    2. Christoforidis GA,
    3. Saadat N, et al
    . Absolute quantitative MR perfusion and comparison against stable-isotope microspheres. Magn Reson Med 2019;81:3567–77 doi:10.1002/mrm.27669 pmid:30737833
    CrossRefPubMed
  10. 10.↵
    1. Liu M,
    2. Saadat N,
    3. Jeong YI, et al
    . Augmentation of perfusion with simultaneous vasodilator and inotropic agents in experimental acute middle cerebral artery occlusion: a pilot study. J Neurointerv Surg 2023;15:e69–75 doi:10.1136/jnis-2022-018990
    CrossRef
  11. 11.↵
    1. Harris RJ,
    2. Bookheimer SY,
    3. Cloughesy TF, et al
    . Altered functional connectivity of the default mode network in patients with cerebral gliomas measured with pseudo-resting state fMRI. PJ Neurooncol 2023;15:e373–79 doi:10.1007/s11060-013-1304-2
    CrossRef
  12. 12.↵
    1. Arthur W. Toga
    1. Eickhoff SB,
    2. Müller VI
    . Functional connectivity. In: Arthur W. Toga, ed. Brain Mapping: An Encyclopedic Reference. Vol. 2. Elsevier; 2015:187–201
    CrossRef
  13. 13.↵
    1. Christoforidis GA,
    2. Rink C,
    3. Kontzialis MS, et al
    . An endovascular canine middle cerebral artery occlusion model for the study of leptomeningeal collateral recruitment. Invest Radiology 2011;46:34–40 doi:10.1097/RLI.0b013e3181f0cbc7 pmid:20856126
    CrossRefPubMed
  14. 14.↵
    1. Kyathanahally SP,
    2. Jia H,
    3. Pustovyy OM, et al
    . Anterior–posterior dissociation of the default mode network in dogs. Brain Struct Funct 2015;220:1063–76 doi:10.1007/s00429-013-0700-x pmid:24399180
    CrossRefPubMed
  15. 15.↵
    1. Lopes R,
    2. Bournonville C,
    3. Kuchcinski G, et al
    . Prediction of long-term cognitive function after minor stroke using functional connectivity. Neurology 2021;96:e1167–79 doi:10.1212/WNL.0000000000011452 pmid:33402437
    Abstract/FREE Full Text
  16. 16.↵
    1. Carter AR,
    2. Shulman GL,
    3. Corbetta M
    . Why use a connectivity-based approach to study stroke and recovery of function? NeuroImage 2012;62:2271–80 doi:10.1016/j.neuroimage.2012.02.070 pmid:22414990
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Woolrich MW,
    2. Jbabdi S,
    3. Patenaude B, et al
    . Bayesian analysis of neuroimaging data in FSL. NeuroImage 2009;45:S173–86 doi:10.1016/j.neuroimage.2008.10.055 pmid:19059349
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Smith SM,
    2. Jenkinson M,
    3. Woolrich MW, et al
    . Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage 2004;23(Suppl 1):S208–19 doi:10.1016/j.neuroimage.2004.07.051 pmid:15501092
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Jenkinson M,
    2. Beckmann CF,
    3. Behrens TE, et al
    . FSL. NeuroImage 2012;62:782–90 doi:10.1016/j.neuroimage.2011.09.015 pmid:21979382
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Jenkinson M,
    2. Bannister P,
    3. Brady JM, et al
    . Improved optimisation for the robust and accurate linear registration and motion correction of brain images. NeuroImage 2002;17:825–41 doi:10.1006/nimg.2002.1132
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Jenkinson M,
    2. Smith SM
    . A global optimisation method for robust affine registration of brain images. Med Image Anal 2001;5:143–56 doi:10.1016/s1361-8415(01)00036-6 pmid:11516708
    CrossRefPubMedWeb of Science
  22. 22.↵
    1. Andersson JLR,
    2. Jenkinson M,
    3. Smith S
    . Non-linear registration, aka spatial normalisation. FMRIB technical report TR07JA2. 2010.
  23. 23.↵
    1. Beckmann KM,
    2. Wang-Leandro A,
    3. Richter H, et al
    . Increased resting state connectivity in the anterior default mode network of idiopathic epileptic dogs. Sci Rep 2021;11:23854 doi:10.1038/s41598-021-03349-x pmid:34903807
    CrossRefPubMed
  24. 24.↵
    1. Johnson PJ,
    2. Luh W-M,
    3. Rivard BC, et al
    . Stereotactic cortical atlas of the domestic canine brain. Sci Rep 2020;10:4781 doi:10.1038/s41598-020-61665-0 pmid:32179861
    CrossRefPubMed
  25. 25.↵
    1. Nieto-Castanon A,
    2. Whitfield-Gabrieli S
    . CONN functional connectivity toolbox: RRID SCR_009550, release 22. Hilbert Press; 2022.
  26. 26.↵
    1. Hebb DO
    . The Organization of Behavior: A Neuropsychological Story. Wiley & Sons; 1949.
  27. 27.↵
    1. Gorges M,
    2. Roselli F,
    3. Müller H-P, et al
    . Functional connectivity mapping in the animal model: principles and applications of resting-state FMRI. Front Neurol 2017;8:200 doi:10.3389/fneur.2017.00200 pmid:28539914
    CrossRefPubMed
  28. 28.↵
    1. Parker DB,
    2. Razlighi QR
    . Task-evoked negative BOLD response and functional connectivity in the default mode network are representative of two overlapping but separate neurophysiological processes. Sci Rep 2019;9:14473 doi:10.1038/s41598-019-50483-8 pmid:31597927
    CrossRefPubMed
  29. 29.↵
    1. Thiel A,
    2. Vahdat S
    . Structural and resting-state brain connectivity of motor networks after stroke. Stroke 2015;46:296–301 doi:10.1161/STROKEAHA.114.006307 pmid:25477218
    FREE Full Text
  30. 30.↵
    1. Wu W,
    2. Sun J,
    3. Jin Z, et al
    . Impaired neuronal synchrony after focal ischemic stroke in elderly patients. Clin Neurophysiol 2011;122:21–26 doi:10.1016/j.clinph.2010.06.003 pmid:20591730
    CrossRefPubMed
  31. 31.↵
    1. Golestani A-M,
    2. Tymchuk S,
    3. Demchuk A, et al
    ; VISION-2 Study Group. Longitudinal evaluation of resting-state FMRI after acute stroke with hemiparesis. Neurorehabil Neural Repair 2013;27:153–63 doi:10.1177/1545968312457827 pmid:22995440
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 45 (9)
American Journal of Neuroradiology
Vol. 45, Issue 9
1 Sep 2024
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Efficacy Assessment of Cerebral Perfusion Augmentation through Functional Connectivity in an Acute Canine Stroke Model
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Chisondi S. Warioba, Mira Liu, Sagada Peñano, Timothy J. Carroll, Sean Foxley, Gregory Christoforidis
Efficacy Assessment of Cerebral Perfusion Augmentation through Functional Connectivity in an Acute Canine Stroke Model
American Journal of Neuroradiology Sep 2024, 45 (9) 1214-1219; DOI: 10.3174/ajnr.A8320

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Cerebral Perfusion Augmentation in Canine Stroke
Chisondi S. Warioba, Mira Liu, Sagada Peñano, Timothy J. Carroll, Sean Foxley, Gregory Christoforidis
American Journal of Neuroradiology Sep 2024, 45 (9) 1214-1219; DOI: 10.3174/ajnr.A8320
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Supplemental
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • PubMed
  • Google Scholar

Cited By...

  • A Method for Imaging the Ischemic Penumbra with MRI Using Intravoxel Incoherent Motion
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire