Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Review ArticleBrain Tumor Imaging
Open Access

The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know

A.G. Osborn, D.N. Louis, T.Y. Poussaint, L.L. Linscott and K.L. Salzman
American Journal of Neuroradiology July 2022, 43 (7) 928-937; DOI: https://doi.org/10.3174/ajnr.A7462
A.G. Osborn
aFrom the Department of Radiology and Imaging Sciences (A.G.O., K.L.S.), University of Utah School of Medicine, Salt Lake City, Utah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A.G. Osborn
D.N. Louis
bDepartment of Pathology (D.N.L.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.N. Louis
T.Y. Poussaint
cDepartment of Radiology (T.Y.P.), Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for T.Y. Poussaint
L.L. Linscott
dIntermountain Pediatric Imaging (L.L.L.), Primary Children's Hospital, University of Utah School of Medicine, Salt Lake City, Utah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L.L. Linscott
K.L. Salzman
aFrom the Department of Radiology and Imaging Sciences (A.G.O., K.L.S.), University of Utah School of Medicine, Salt Lake City, Utah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for K.L. Salzman
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Louis DN,
    2. Aldape K,
    3. Brat DJ, et al
    . Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathol 2017;133:1–3 doi:10.1007/s00401-016-1646-x pmid:27909809
    CrossRefPubMed
  2. 2.↵
    1. Louis DN,
    2. Aldape K,
    3. Brat DJ, et al
    . cIMPACT-NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathol 2017;27:851–52 doi:10.1111/bpa.12457 pmid:27997995
    CrossRefPubMed
  3. 3.↵
    1. Louis DN,
    2. Wesseling P,
    3. Paulus W, et al
    . cIMPACT-NOW update 1: not otherwise specified (NOS) and not elsewhere classified (NEC). Acta Neuropathol 2018;135:481–84 doi:10.1007/s00401-018-1808-0 pmid:29372318
    CrossRefPubMed
  4. 4.↵
    1. Louis DN,
    2. Giannini C,
    3. Capper D, et al
    . cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant. Acta Neuropathol 2018;135:639–42 doi:10.1007/s00401-018-1826-y pmid:29497819
    CrossRefPubMed
  5. 5.↵
    1. Brat DJ,
    2. Aldape K,
    3. Colman H, et al
    . cIMPACT-NOW update 3: recommended diagnostic criteria for “diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV.” Acta Neuropathol 2018;136:805–10 doi:10.1007/s00401-018-1913-0 pmid:30259105
    CrossRefPubMed
  6. 6.↵
    1. Ellison DW,
    2. Hawkins C,
    3. Jones DTW, et al
    . cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAF V600E mutation. Acta Neuropathol 2019;137:683–87 doi:10.1007/s00401-019-01987-0 pmid:30848347
    CrossRefPubMed
  7. 7.↵
    1. Brat DJ,
    2. Aldape K,
    3. Colman H, et al
    . cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas. Acta Neuropathol 2020;139:603–08 doi:10.1007/s00401-020-02127-9 pmid:31996992
    CrossRefPubMed
  8. 8.↵
    1. Louis DN,
    2. Wesseling P,
    3. Aldape K, et al
    . cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-UTRECHT meeting on future CNS tumor classification and grading. Brain Pathol 2020;30:844–56 doi:10.1111/bpa.12832 pmid:32307792
    CrossRefPubMed
  9. 9.↵
    1. Ellison DW,
    2. Aldape KD,
    3. Capper D, et al
    . cIMPACT-NOW update 7: advancing the molecular classification of ependymal tumors. Brain Pathol 2020;30:863–66 doi:10.1111/bpa.12866 pmid:32502305
    CrossRefPubMed
  10. 10.↵
    1. Louis DN,
    2. Ellison DW,
    3. Brat DJ, et al
    . cIMPACT-NOW: a practical summary of diagnostic points from Round 1 updates. Brain Pathol 2019;29:469–72 doi:10.1111/bpa.12732 pmid:31038238
    CrossRefPubMed
  11. 11.↵
    WHO Classification of Tumours Editorial Board. World Health Organization Classification of Tumours of the Central Nervous System. 5th ed: Lyon: International Agency for Research on Cancer; 2021
  12. 12.↵
    1. Batchala PP,
    2. Muttikkal TJ,
    3. Donahue JH, et al
    . Neuroimaging-based classification algorithm for predicting 1p/19q-codeletion status in IDH-mutant lower grade gliomas. AJNR Am J Neuroradiol 2019;40:426–42 doi:10.3174/ajnr.A5957 pmid:30705071
    Abstract/FREE Full Text
  13. 13.↵
    1. Patel SH,
    2. Poisson LM,
    3. Brat DJ, et al
    . T2-FLAIR mismatch, an imaging biomarker for IDH and 1p/19q status in lower-grade gliomas: a TCGA/TCIA project. Clin Cancer Res 2017;23:6078–85 doi:10.1158/1078-0432.CCR-17-0560 pmid:28751449
    Abstract/FREE Full Text
  14. 14.↵
    1. Doig D,
    2. Kachramanoglou C,
    3. Dumba
    M, et al. Characterisation of isocitrate dehydrogenase gene mutant WHO grade 2 and 3 gliomas: MRI predictors of 1p/19q co-deletion and tumour grade. Clin Radiol 2021;76:785 doi:10.1016/j.crad.2021.06.015 pmid:34289936
    CrossRefPubMed
  15. 15.↵
    1. Chen Y,
    2. Tian T,
    3. Guo X, et al
    . Polymorphous low-grade neuroepithelial tumor of the young: case report and review focus on the radiological features and genetic alterations. BMC Neurol 2020;20:123 doi:10.1186/s12883-020-01679-3 pmid:32252664
    CrossRefPubMed
  16. 16.↵
    1. Benson JC,
    2. Summerfield D,
    3. Carr C, et al
    . Polymorphous low-grade neuroepithelial tumor of the young as a partially calcified intra-axial mass in an adult. AJNR Am J Neuroradiol 2020;41:573–78 doi:10.3174/ajnr.A6500 pmid:32217553
    Abstract/FREE Full Text
  17. 17.↵
    1. Ryall S,
    2. Zapotocky M,
    3. Fukuoka K, et al
    . Integrated molecular and clinical analysis of 1,000 pediatric low-grade gliomas. Cancer Cell 2020;37:569–83 doi:10.1016/j.ccell.2020.03.011 pmid:32289278
    CrossRefPubMed
  18. 18.↵
    1. Ross JL,
    2. Velazquez Vega J,
    3. Plant A, et al
    . Tumor immune landscape of paediatric high-grade gliomas. Brain 2021;144:2594–2609 doi:10.1093/brain/awab155 pmid:33856022
    CrossRefPubMed
  19. 19.↵
    1. Roux A,
    2. Pallud J,
    3. Saffroy R, et al
    . High-grade gliomas in adolescents and young adults highlight histomolecular differences from their adult and pediatric counterparts. Neuro Oncol 2020;22:1190–1202 doi:10.1093/neuonc/noaa024 pmid:32025728
    CrossRefPubMed
  20. 20.↵
    1. Yekula A,
    2. Gupta M,
    3. Coley N, et al
    . Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: case report and review of the literature. Int J Surg Case Rep 2020;68:124–28 doi:10.1016/j.ijscr.2020.02.046 pmid:32145563
    CrossRefPubMed
  21. 21.↵
    1. Aboian MS,
    2. Solomon DA,
    3. Felton E, et al
    . Imaging characteristics of pediatric diffuse midline gliomas with histone H3 K27M mutation. AJNR Am J Neuroradiol 2017;38:795–800 doi:10.3174/ajnr.A5076 pmid:28183840
    Abstract/FREE Full Text
  22. 22.↵
    1. Muñoz Pérez JP,
    2. Muchart J,
    3. Santa-María López V, et al
    . Targeted therapy for pediatric low-grade glioma. Childs Nerv Syst 2021;37:2511–20 doi:10.1007/s00381-021-05138-3 pmid:33864514
    CrossRefPubMed
  23. 23.↵
    1. Bender K,
    2. Perez E,
    3. Chirica M, et al
    . High-grade astrocytoma with piloid features (HGAP): the Charite experience with a new central nervous system tumor entity. J Neurooncol 2021;153:109–20 doi:10.1007/s11060-021-03749-z pmid:33905054
    CrossRefPubMed
  24. 24.↵
    1. Chen W,
    2. Soon YY,
    3. Pratiseyo PD, et al
    . Central nervous system neuroepithelial tumors with MN1-alteration: an individual patient data meta-analysis of 73 cases. Brain Tumor Pathol 2020;37:145–53 doi:10.1007/s10014-020-00372-0 pmid:32601775
    CrossRefPubMed
  25. 25.↵
    1. Hirose T,
    2. Nobusawa S,
    3. Sugiyama K, et al
    . Astroblastoma: a distinct tumor entity characterized by alterations of the X chromosome and MN1 rearrangement. Brain Pathol 2018;28:684–94 doi:10.1111/bpa.12565 pmid:28990708
    CrossRefPubMed
  26. 26.↵
    1. Mhatre R,
    2. Sugur HS,
    3. Nandeesh BN
    , et al. MN1 rearrangement in astroblastoma: study of eight cases and review of literature. Brain Tumor Pathol 2019;36:112–20 doi:10.1007/s10014-019-00346-x pmid:31111274
    CrossRefPubMed
  27. 27.↵
    1. Deng MY,
    2. Sill M,
    3. Sturm D, et al
    . Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC): a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14. Neuropathol Appl Neurobiol 2020;46:422–30 doi:10.1111/nan.12590 pmid:31867747
    CrossRefPubMed
  28. 28.↵
    1. Lucas CH,
    2. Villanueva-Meyer JE,
    3. Whipple N, et al
    . Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. Brain Pathol 2020;30:479–94 doi:10.1111/bpa.12797 pmid:31609499
    CrossRefPubMed
  29. 29.↵
    1. Chiang JC,
    2. Harreld JH,
    3. Tanaka R, et al
    . Septal dysembryoplastic neuroepithelial tumor: a comprehensive clinical, imaging, histopathologic, and molecular analysis. Neuro Oncol 2019;21:800–08 doi:10.1093/neuonc/noz037 pmid:30726976
    CrossRefPubMed
  30. 30.↵
    1. Lecler A,
    2. Broquet V,
    3. Bailleux J, et al
    . Advanced multiparametric magnetic resonance imaging of multinodular and vacuolating neuronal tumor. Eur J Neurol 2020;27:1561–69 doi:10.1111/ene.14264 pmid:32301260
    CrossRefPubMed
  31. 31.↵
    1. Nunes RH,
    2. Hsu CC,
    3. da Rocha AJ, et al
    . Multinodular and vacuolating neuronal tumor of the cerebrum: a new “leave me alone” lesion with a characteristic imaging pattern. AJNR Am J Neuroradiol 2017;38:1899–1904 doi:10.3174/ajnr.A5281 pmid:28705817
    Abstract/FREE Full Text
  32. 32.↵
    1. Lecler A,
    2. Bailleux J,
    3. Carsin B, et al
    ; ENIGMA Investigation Group (EuropeaN Interdisciplinary Group for MVNT Analysis). Multinodular and vacuolating posterior fossa lesions of unknown significance. AJNR Am J Neuroradiol 2019;40:1689–94 doi:10.3174/ajnr.A6223 pmid:31558497
    Abstract/FREE Full Text
  33. 33.↵
    1. Kupp R,
    2. Ruff L,
    3. Terranova S, et al
    . ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors. Cancer Discov 2021;11:2216–29 doi:10.1158/2159-8290.CD-20-1052 pmid:33741711
    Abstract/FREE Full Text
  34. 34.↵
    1. Wang G,
    2. Jia Y,
    3. Ye Y, et al
    . Identification of key methylation differentially expressed genes in posterior fossa ependymoma based on epigenomic and transcriptome analysis. J Transl Med 2021;19:174 doi:10.1186/s12967-021-02834-1 pmid:33902636
    CrossRefPubMed
  35. 35.↵
    1. Witt H,
    2. Mack SC,
    3. Ryzhova M, et al
    . Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma. Cancer Cell 2011;20:143–57 doi:10.1016/j.ccr.2011.07.007 pmid:21840481
    CrossRefPubMedWeb of Science
  36. 36.↵
    1. Raffeld M,
    2. Abdullaev Z,
    3. Pack SD, et al
    . High level MYCN amplification and distinct methylation signature define an aggressive subtype of spinal cord ependymoma. Acta Neuropathol Commun 2020;8:101 doi:10.1186/s40478-020-00973-y pmid:32641156
    CrossRefPubMed
  37. 37.↵
    1. Reis J,
    2. Stahl R,
    3. Zimmermann H, et al
    . Advanced MRI findings in medulloblastomas: relationship to genetic subtypes, histopathology, and immunohistochemistry. J Neuroimaging 2021;31:306–16 doi:10.1111/jon.12831 pmid:33465267
    CrossRefPubMed
  38. 38.↵
    1. Coltin H,
    2. Sundaresan L,
    3. Smith KS, et al
    . Subgroup and subtype-specific outcomes in adult medulloblastoma. Acta Neuropathol 2021;142:859–71 doi:10.1007/s00401-021-02358-4 pmid:34409497
    CrossRefPubMed
  39. 39.↵
    1. Skowron P,
    2. Farooq H,
    3. Cavalli FM, et al
    . The transcriptional landscape of SHH medulloblastoma. Nat Comm 2021;12:1749 doi:10.1038/s41467-021-21883-0 pmid:33741928
    CrossRefPubMed
  40. 40.↵
    1. Cai C
    . SWI/SNF deficient central nervous system neoplasms. Semin Diagn Pathol 2021;38:167–74 doi:10.1053/j.semdp.2021.03.003 pmid:33762087
    CrossRefPubMed
  41. 41.↵
    1. Tauziede-Espariat A,
    2. Pierron G,
    3. Seigfried A, et al
    . The EP300:BCOR fusion extends the genetic alteration spectrum defining the new tumoral entity of “CNS tumors with BCOR internal tandem duplication.” Acta Neuropathol Commun 2020;8:178 doi:10.1186/s40478-020-01064-8 pmid:33138864
    CrossRefPubMed
  42. 42.↵
    1. Shih RY,
    2. Koeller KK
    . Embryonal tumors of the central nervous system: from the radiologic pathology archives. Radiographics 2018;38:525–41 doi:10.1148/rg.2018170182 pmid:29528832
    CrossRefPubMed
  43. 43.↵
    1. Korshunov A,
    2. Okonechnikov K,
    3. Schmitt-Hoffner F, et al
    . Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation. Acta Neuropathol Commun 2021;9:20 doi:10.1186/s40478-021-01118-5 pmid:33536079
    CrossRefPubMed
  44. 44.↵
    1. Thomas C,
    2. Wefers A,
    3. Bens S, et al
    . Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults. Acta Neuropathol 2020:277–86 doi:10.1007/s00401-019-02094-w pmid:31732806
    CrossRefPubMed
  45. 45.↵
    1. Louis DN,
    2. Perry A,
    3. Wesseling P
    , et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol 2021;23:1231–51 doi:10.1093/neuonc/noab106 pmid:34185076
    CrossRefPubMed
  46. 46.↵
    1. Lopes MB
    . The 2017 World Health Organization Classification of Tumors of the Pituitary Gland: a summary. Acta Neuropathol 2017;134:521–55 doi:10.1007/s00401-017-1769-8 pmid:28821944
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 43 (7)
American Journal of Neuroradiology
Vol. 43, Issue 7
1 Jul 2022
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
A.G. Osborn, D.N. Louis, T.Y. Poussaint, L.L. Linscott, K.L. Salzman
The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know
American Journal of Neuroradiology Jul 2022, 43 (7) 928-937; DOI: 10.3174/ajnr.A7462

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
2021 WHO CNS Tumor Classification for Radiologists
A.G. Osborn, D.N. Louis, T.Y. Poussaint, L.L. Linscott, K.L. Salzman
American Journal of Neuroradiology Jul 2022, 43 (7) 928-937; DOI: 10.3174/ajnr.A7462
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Mesenchymal Nonmeningothelial Tumors of the CNS: Evolving Molecular Landscape and Implications for Neuroradiologists
  • Ependymal Tumors: Overview of the Recent World Health Organization Histopathologic and Genetic Updates with an Imaging Characteristic
  • High-Grade Astrocytoma with Piloid Features: A Dual Institutional Review of Imaging Findings of a Novel Entity
  • Theranostics in Neurooncology: Heading Toward New Horizons
  • Modeling Glioma Oncostreams In Vitro: Spatiotemporal Dynamics of their Formation, Stability, and Disassembly
  • Comparison of the Diagnostic Performance from Patients Medical History and Imaging Findings between GPT-4 based ChatGPT and Radiologists in Challenging Neuroradiology Cases
  • PiDeeL: Pathway-Informed Deep Learning Model for Survival Analysis and Pathological Classification of Gliomas
  • Newly Recognized CNS Tumors in the 2021 World Health Organization Classification: Imaging Overview with Histopathologic and Genetic Correlation
  • Amino Acid Tracer PET MRI in Glioma Management: What a Neuroradiologist Needs to Know
  • Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant SMO and GLI into Glioma Primary Cilia
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Brain Tumor Subtyping Image-Based search via MRI
  • Neuroimaging of Erdheim-Chester Disease
  • CE MRI for Brain Metastasis Detection
Show more Brain Tumor Imaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire