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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleSpine Imaging and Spine Image-Guided Interventions
Open Access

Spontaneous Spinal CSF Leaks Stratified by Age, Body Mass Index, and Spinal Level

M.D. Mamlouk, P.Y. Shen, P. Jun and M.F. Sedrak
American Journal of Neuroradiology July 2022, 43 (7) 1068-1072; DOI: https://doi.org/10.3174/ajnr.A7548
M.D. Mamlouk
aFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California
bDepartment of Radiology and Biomedical Imaging (M.D.M.), University of California, San Francisco, San Francisco, California
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P.Y. Shen
aFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California
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P. Jun
aFrom the Department of Radiology (M.D.M., P.Y.S., P.J.), The Permanente Medical Group, Kaiser Permanente Medical Center, Santa Clara, Santa Clara, California
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M.F. Sedrak
cDepartment of Neurosurgery (M.F.S.), The Permanente Medical Group, Kaiser Permanente Medical Center, Redwood City, Redwood City, California
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Article Figures & Data

Figures

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  • FIG 1.
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    FIG 1.

    Type 1 CSF leak (dural tear): dynamic CT prone myelogram in the sagittal plane shows normal myelographic contrast in the subarachnoid space (white arrow) until there is a transition point at the T1–T2 level where there is a calcified disc (black arrowhead) that results in a split of contrast between the subarachnoid and ventral extradural spaces (black arrow).

  • FIG 2.
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    FIG 2.

    Type 2 CSF leak (ruptured meningeal diverticulum): left decubitus CT myelogram in the axial plane shows contrast leaking from the left T9–T10 meningeal diverticulum into the neural foramen (arrow).

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    FIG 3.

    Type 3 CSF leak (CVF): right decubitus CT myelogram in the axial plane shows a paraspinal vein (arrows) that was contiguous with the right T10–T11 meningeal diverticulum.

Tables

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  • Patient demographics of spinal CSF leaks

    DemographicsAll PatientsType 1Type 2Type 3P Valuea
    No. of leaks6525 (39%)4 (6%)36 (55%)
    Age at symptoms onset (yr)<.00001
     Mean (SD)52.4 (13.1)44.5 (10.3)45.5 (8.1)58.8 (11.9)
     95% CI49.3–55.640.4–48.537.6–53.454.9–62.6
     Range28–9128–6834–5339–91
    Sex (No.).81
     Female3714419
     Male2811017
    BMI.015
     Mean (SD)26.0 (4.5)24.3 (3.1)27.5 (7.9)27.0 (4.7)
     95% CI24.9–27.123.1–25.519.7–35.325.4–28.5
     Range16–3918–3121–3916–39
    Leak location (No.)<.0002
     Cervical2200
     Upper thoracic (T1–T6)3118013
     Lower thoracic (T7–T12)295420
     Lumbar3003
    Bern SIH score.44
     Mean (SD)5.7 (2.4)5.4 (2.0)5.8 (3.3)5.9 (2.6)
     Range0–90–81–80–9
    • ↵a P values were compared between type 1 and 3 groups.

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American Journal of Neuroradiology: 43 (7)
American Journal of Neuroradiology
Vol. 43, Issue 7
1 Jul 2022
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Cite this article
M.D. Mamlouk, P.Y. Shen, P. Jun, M.F. Sedrak
Spontaneous Spinal CSF Leaks Stratified by Age, Body Mass Index, and Spinal Level
American Journal of Neuroradiology Jul 2022, 43 (7) 1068-1072; DOI: 10.3174/ajnr.A7548

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Spontaneous Spinal CSF Leaks: Age and BMI Factors
M.D. Mamlouk, P.Y. Shen, P. Jun, M.F. Sedrak
American Journal of Neuroradiology Jul 2022, 43 (7) 1068-1072; DOI: 10.3174/ajnr.A7548
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