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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Utility of Dual-Energy CT to Improve Diagnosis of CSF Leaks on CT Myelography following Lateral Decubitus Digital Subtraction Myelography with Negative Findings

S.J. Huls, D.P. Shlapak, D.K. Kim, S. Leng and C.M. Carr
American Journal of Neuroradiology October 2022, 43 (10) 1539-1543; DOI: https://doi.org/10.3174/ajnr.A7628
S.J. Huls
aFrom the Department of Radiology, Mayo Clinic, Ringgold Standard Institution, Rochester, Minnesota
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D.P. Shlapak
aFrom the Department of Radiology, Mayo Clinic, Ringgold Standard Institution, Rochester, Minnesota
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D.K. Kim
aFrom the Department of Radiology, Mayo Clinic, Ringgold Standard Institution, Rochester, Minnesota
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S. Leng
aFrom the Department of Radiology, Mayo Clinic, Ringgold Standard Institution, Rochester, Minnesota
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C.M. Carr
aFrom the Department of Radiology, Mayo Clinic, Ringgold Standard Institution, Rochester, Minnesota
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  • FIG 1.
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    FIG 1.

    A, 50-keV VMI. B, 100 kV. C, 140 kV. Case 1: Left-side-down CTM with linear contrast at the left T12–L1 neural foramen, thought to reflect a CVF (arrows). Contrast is also noted in the renal collecting system. ROI Hounsfield units: A, 50-keV VMI Hounsfield unit maximum (max): 283 HU; mean, 76 HU. B, 100 -kV Hounsfield unit max: 147 HU; mean, 68 HU. C, 140-kV Hounsfield unit max: 116 HU; mean, 46 HU. D, 50-keV VMI. E, 100 kV. F, 140 kV. Case 1: Right-side-down CTM with paraspinal contrast at the level of T11–12, representing a second CVF (arrows). ROI Hounsfield units: D, 50-keV VMI Hounsfield unit max: 981 HU; mean, 693 HU. E, 100-kV Hounsfield unit max: 542 HU; mean, 369 HU. F, 140-kV Hounsfield unit max: 233 HU; mean, 107 HU.

  • FIG 2.
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    FIG 2.

    A, 50-keV VMI. B, 100 kV. C, 140 kV. Case 2: Left-side-down CTM with a suspected distal nerve root sleeve tear at the left L2–3 (arrows). The patient also had contrast in the renal collecting system (not shown). ROI Hounsfield units: A, 50-keV VMI Hounsfield unit maximum (max): 806 HU; mean, 271 HU. B, 100-kV Hounsfield unit max: 435 HU; mean, 133 HU. C, 140-kV Hounsfield unit max: 210 HU; mean, 68 HU.

  • FIG 3.
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    FIG 3.

    A, 50 -keV VMI. B, 100 kV. C, 150 kV. Case 3: Right-side-down CTM with linear contrast at the right L2–3 neuroforamen (arrows), extending into the paraspinal soft tissues, thought to reflect a vessel associated with contrast leakage at a higher right-T10 distal nerve root sleeve tear (not shown). ROI Hounsfield units: A, 50-keV VMI Hounsfield unit maximum (max): 485 HU; mean, 118 HU. B, 100-kV Hounsfield unit max: 271 HU; mean, 51 HU. C, 150-kV Hounsfield unit max: 151 HU; mean, 16 HU.

  • FIG 4.
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    FIG 4.

    A, 50-keV VMI. B, 100 kV. C, 140 kV. Case 4: Right-side-down CTM with a small focus of extradural contrast at the right aspect of the thecal sac at T7–8 (arrows). ROI Hounsfield units: A, 50-keV VMI Hounsfield unit maximum (max): 441 HU; mean, 275 HU). B, 100-kV Hounsfield unit max: 277 HU; mean, 165 HU. C, 140-kV Hounsfield unit max: 163 HU; mean, 102 HU.

  • FIG 5.
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    FIG 5.

    A, 50-keV VMI. B, 100 kV. C, 140 kV. Case 5: CTM right-side-down at the level of T11–12 shows linear focus most consistent with a CSF venous fistula (arrows). ROI Hounsfield units: A, 50-keV Hounsfield unit maximum (max): 436 HU; mean, 154 HU. B, 100-kV Hounsfield unit max: 251 HU; mean, 88 HU. C, 140-kV Hounsfield unit max: 125 HU; mean, 33 HU.

Tables

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    Table 1:

    Parameters for CT cervical, thoracic, and lumbar spine myelogram (Siemens dual-source, dual-energy CT models)

    DECT ModelSomatom Definition FlashSomatom Force
    Description128-Section dual-source, dual-energy CT192-Section dual-source, dual-energy CT
    kV(p)A: 100 B: Sn 140A: 100 B: Sn 150
    Quality reference mAsA: 230 B: 178A: 260 B: 130
    Scan FOV (mm)A: 500 B: 332A: 500 B: 356
    Rotation time (sec)1.01.0
    Pitch0.90.9
    Collimation (mm)32 × 0.6128 × .06
    • View popup
    Table 2:

    Patient demographics, imaging findings, symptoms, treatment, and outcomes

    PatientAgeSexOther Imaging FindingsCTM FindingsSymptomsTreatmentOutcome
    128FHigh-probability brain MR imagingT12-L1 CVF on left; T11-12 on right; contrast in the renal collecting systemOrthostatic headache, multifocal painT11 nerve root ligationInitial relief with subsequent recurrence of symptoms in the setting of Marfan syndrome
    250MIntermediate-probability brain MR imagingCVF at left L2-3 and contrast in the renal collecting systemOrthostatic headacheBlood patch, transvenous embolization of the left L2 paraspinal veinDramatic symptom improvement following embolization
    352MHigh-probability brain MR imaging, positive cisternogram findingsRight T10 distal nerve root sleeve tear with extradural contrast first detected at L2-3Orthostatic headache, vision changes, pulsatile tinnitusHemi-laminectomy right T10-11, repair of CSF leakComplete symptom resolution sustained for at least 1 year
    434FIntermediate-probability brain MR imagingFocus of CSF leak arising from the right lateral thecal sac at T7-8 thought to represent dural tear; contrast in the renal collecting systemOrthostatic headache, facial and hand paresthesiaThree targeted blood patchesImprovement after 3 targeted blood patches with recurrence of symptoms
    550FMultiple nerve root diverticula on spine MR imagingFaint linear hyperattenuation extending from a right T11-12 nerve sleeve diverticulum thought to represent CVFOrthostatic headache, vision changesTwo targeted and 1 multifocal blood patchTransient improvement after 2 targeted and 1 multifocal blood patch
    • Note:—M indicates male; F, female.

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    Table 3:

    Hounsfield measurements at the site of contrast leak or CVF

    Case50 keV VMI Mean50 keV VMI Max100 kV Mean100 kV Max140/150 kV Mean140/150 kV Max
    Case 1L762836814746116
    Case 1R693981369542107233
    Case 227180613343568210
    Case 31184855127116150
    Case 4275441165277102163
    Case 51544368825133125
    • Note:—1L indicates left side down CTM; 1R, right side down CTM

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American Journal of Neuroradiology: 43 (10)
American Journal of Neuroradiology
Vol. 43, Issue 10
1 Oct 2022
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S.J. Huls, D.P. Shlapak, D.K. Kim, S. Leng, C.M. Carr
Utility of Dual-Energy CT to Improve Diagnosis of CSF Leaks on CT Myelography following Lateral Decubitus Digital Subtraction Myelography with Negative Findings
American Journal of Neuroradiology Oct 2022, 43 (10) 1539-1543; DOI: 10.3174/ajnr.A7628

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Dual-Energy CT for CSF Leaks Diagnosis
S.J. Huls, D.P. Shlapak, D.K. Kim, S. Leng, C.M. Carr
American Journal of Neuroradiology Oct 2022, 43 (10) 1539-1543; DOI: 10.3174/ajnr.A7628
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