Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy

A. Vuong, E.G. Fowler, J. Matsumoto, L.A. Staudt, H. Yokota and S.H. Joshi
American Journal of Neuroradiology November 2021, 42 (11) 2054-2061; DOI: https://doi.org/10.3174/ajnr.A7272
A. Vuong
aFrom the Departments of Bioengineering (A.V., S.H.J.)
bOrthopaedic Surgery (A.V., E.G.F., L.A.S.)
eCenter for Cerebral Palsy at UCLA/Orthopaedic Institute for Children (A.V., E.G.F., L.A.S.), Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for A. Vuong
E.G. Fowler
bOrthopaedic Surgery (A.V., E.G.F., L.A.S.)
eCenter for Cerebral Palsy at UCLA/Orthopaedic Institute for Children (A.V., E.G.F., L.A.S.), Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for E.G. Fowler
J. Matsumoto
cPediatrics (J.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for J. Matsumoto
L.A. Staudt
bOrthopaedic Surgery (A.V., E.G.F., L.A.S.)
eCenter for Cerebral Palsy at UCLA/Orthopaedic Institute for Children (A.V., E.G.F., L.A.S.), Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for L.A. Staudt
H. Yokota
fDepartment of Diagnostic Radiology and Radiation (H.Y.), Chiba University Hospital, Chiba, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for H. Yokota
S.H. Joshi
aFrom the Departments of Bioengineering (A.V., S.H.J.)
dAhmanson-Lovelace Brain Mapping Center in the Department of Neurology (S.H.J.), University of California Los Angeles, Los Angeles, California
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S.H. Joshi
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • FIG 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 1.

    TBSS results show significant differences (P <.05) in DTI measures between the CP and TDC groups. Coronal slices were selected at the level of the CST. From left to right, axial slices were selected at the level of the motor cortex, PLIC, and CerPed, respectively. Mid-sagittal slices were selected at the level of the CC. A, The WM skeleton is shown in green with arrows labeling the CST, somatosensory cortex, parietal lobe, external capsule, PLIC, anterior limb of the internal capsule (ALIC), and corpus callosum. In the coronal view, ROIs for the SCR (red), PLIC (yellow), CerPed (blue), and sub-CerPed (orange) are shown. Significant differences between the CP and TDC groups are shown for FA (B), RD (C), AD (D), and MD (E). The hot colormaps denote whether a DTI measure for the CP group was less than (red-yellow) or greater than (blue-light blue) that in the TDC group. A indicates anterior; FWE, family-wise error; I, inferior; L, left; P, posterior; R, right; S, superior.

  • FIG 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 2.

    Mean differences in DTI measures between the CP and TDC groups within ROIs for the CST and CC. The asterisk indicates significant differences (P <.05). L indicates left; R, right.

  • FIG 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    FIG 3.

    TBSS results show significant correlations (P <.05) between DTI measures and clinical measures for the CP group. Coronal slices were selected at the level of the CST. From left to right, axial slices were selected at the level of the motor cortex, PLIC, and CerPed, respectively. Mid-sagittal slices were selected at the level of the CC. Significant correlations are shown for FA vs. SCALE (A), FA vs. GMFM (B), RD vs. SCALE (C), and RD vs. GMFM (D). The hot colormaps denote whether the correlations were positive (red-yellow) or negative (blue-light blue). A indicates anterior; FWE, family-wise error; I, inferior; L, left; P, posterior; R, right; S, superior.

Tables

  • Figures
  • ROI correlation analyses comparing motor and whole-brain WM regions

    RegionsVoxel CountVoxels with Significant Correlations
    FA vs. SCALE (%)FA vs. GMFM (%)RD vs. SCALE (%)RD vs. GMFM (%)
    CST
     Sub-CerPed R37523 (6.1)0 (0)0 (0)0 (0)
     Sub-CerPed L3950 (0)0 (0)0 (0)0 (0)
     CerPed R598266 (44.5)0 (0)0 (0)0 (0)
     CerPed L62474 (11.9)0 (0)0 (0)0 (0)
     PLIC R845198 (23.4)74 (8.8)0 (0)0 (0)
     PLIC L85820 (2.3)18 (2.1)0 (0)0 (0)
     SCR R1294451 (34.9)387 (29.9)0 (0)0 (0)
     SCR L127994 (7.3)25 (2.0)0 (0)0 (0)
    CC
     Genu17580 (0)0 (0)54 (3.1)0 (0)
     Body31381177 (37.5)692 (22.1)874 (27.9)0 (0)
     Splenium2298904 (39.3)615 (26.8)686 (29.9)0 (0)
    Whole brain126,00038,251 (30.4)18,136 (14.4)2779 (2.2)0 (0)
    • Note:—L indicates left; R, right.

PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 42 (11)
American Journal of Neuroradiology
Vol. 42, Issue 11
1 Nov 2021
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
A. Vuong, E.G. Fowler, J. Matsumoto, L.A. Staudt, H. Yokota, S.H. Joshi
Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy
American Journal of Neuroradiology Nov 2021, 42 (11) 2054-2061; DOI: 10.3174/ajnr.A7272

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Selective Motor Control is a Clinical Correlate of Brain Motor Tract Impairment in Children with Spastic Bilateral Cerebral Palsy
A. Vuong, E.G. Fowler, J. Matsumoto, L.A. Staudt, H. Yokota, S.H. Joshi
American Journal of Neuroradiology Nov 2021, 42 (11) 2054-2061; DOI: 10.3174/ajnr.A7272
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • MATERIALS AND METHODS
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Improved Myelination following Camp Leg Power, a Selective Motor Control Intervention for Children with Spastic Bilateral Cerebral Palsy: A Diffusion Tensor MRI Study
  • Improved Myelination following Camp Leg Power, a Selective Motor Control Intervention for Children with Spastic Bilateral Cerebral Palsy: A Diffusion Tensor MRI Study
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Frontal Paraventricular Cysts
  • Sodium MRI in Pediatric Brain Tumors
  • FRACTURE MR in Congenital Vertebral Anomalies
Show more Pediatric Neuroimaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire