Article Figures & Data
Figures
- FIG 1.
M1 and M2 macrophage populations in aneurysm tissues after endovascular coiling for control and treatment groups. A, Mean number of M1 macrophages ± standard error of the mean. Representative confocal microscopy images of cells staining positive for CD80 (60× oil magnification) at 1 month (C), 3 months (D), and 6 months (E). F, Mean number of M2 macrophages ± standard error of the mean. Representative confocal microscopy images of cells staining positive for CD206 (60× oil magnification) at 1 month (H), 3 months (I), and 6 months (J). B and G, Representative confocal images of control aneurysm tissues stained for CD80 and CD206, respectively, at 1 month (20× oil magnification). Asterisk indicates P < .05; double asterisks, P < .01.
- FIG 2.
Collagen deposition in aneurysm tissues after endovascular coiling for 3 treatment-to-sacrifice time groups. A, Mean percentage of collagen deposition ± standard error of the mean. Photomicrographs of collagen deposition using Masson trichrome stain are shown for 1 month (B), 3 months (C), and 6 months (D) (2.5× magnification; scale bar =0.4 mm). Asterisk indicates P < .05; double asterisks, P < .01.
- FIG 3.
Total histologic healing scores for aneurysm tissues after endovascular coiling for 3 treatment-to-sacrifice time groups.
- FIG 4.
Correlational relationships of M2 macrophages to collagen deposition and histologic grading in aneurysm tissues after endovascular coiling for 3 treatment-to-sacrifice time groups. A, One month posttreatment. B, Three months posttreatment. C, Six months posttreatment.
