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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleAdult Brain

Visualization of Nigrosome 1 from the Viewpoint of Anatomic Structure

N. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo and Y. Shibamoto
American Journal of Neuroradiology January 2020, 41 (1) 86-91; DOI: https://doi.org/10.3174/ajnr.A6338
N. Arai
aFrom the Department of Radiology (N.A., H. Kasai, H. Kunitomo), Nagoya City University Hospital, Nagoya, Japan
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H. Kan
bRadiological and Medical Laboratory Sciences (H. Kan), Nagoya University Graduate School of Medicine, Nagoya, Japan
cDepartments of Radiology (H. Kan, M.O., Y.S.)
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M. Ogawa
cDepartments of Radiology (H. Kan, M.O., Y.S.)
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Y. Uchida
dNeurology (Y.U.), Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
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M. Takizawa
eHealthcare Business Unit (M.T., K.O.), Hitachi Ltd, Tokyo, Japan
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K. Omori
eHealthcare Business Unit (M.T., K.O.), Hitachi Ltd, Tokyo, Japan
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T. Miyati
fDivision of Health Sciences, Graduate School of Medical Science (T.M.), Kanazawa University, Kanazawa, Japan.
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H. Kasai
aFrom the Department of Radiology (N.A., H. Kasai, H. Kunitomo), Nagoya City University Hospital, Nagoya, Japan
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H. Kunitomo
aFrom the Department of Radiology (N.A., H. Kasai, H. Kunitomo), Nagoya City University Hospital, Nagoya, Japan
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Y. Shibamoto
cDepartments of Radiology (H. Kan, M.O., Y.S.)
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Article Figures & Data

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  • Fig 1.
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    Fig 1.

    Volunteers’ heads were held in 1 of 3 ways: tilted to the right (A), not tilted (B), and tilted to the left (C) in the B0 direction.

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    Fig 2.

    The 3D spoiled gradient-echo sequences with multiecho acquisitions are oriented orthogonally to the anterior midbrain (A), and nigrosome 1 is visualized in the caudal and mediolateral part of the substantia nigra pars compacta (B). When the subjects’ heads were tilted to the right or left, the MR imaging signal intensities measured on the basis of the depicted ROI (C) differentiated nigrosome 1 and SNc.

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    Fig 3.

    Visualization of the right (A) and left (B) nigrosome 1, in which the volunteers’ heads were tilted to the right or left in the B0 direction or not at all.

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    Fig 4.

    Examples of visualization of nigrosome 1 with a right head tilt (A), without a head tilt (B), and with a left head tilt (C) in the B0 direction.

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    Fig 5.

    Coronal sections of the 3D susceptibility map (A) and the local field map (B). The anatomic slant structure of nigrosome 1 is coherent between the axis of nigrosome 1 (arrows) and the magic angle that occurs at approximately 54.7° in the B0 direction by dipolar interaction (C).

Tables

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    Table 1:

    Number of visualizations of discriminable nigrosome 1 when the subjects’ heads were tilted in the B0 direction (n = 14)

    Tilting Head in B0 DirectionRightNoneLeft
    Nigrosome 1RightLeftRightLeftRightLeft
    Discriminable nigrosome 1 (No.)99651011
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    Table 2:

    Results of contrast measurement repeated 6 times in 1 volunteer with right head tilting and left head tilting

    Tilting Head in B0 DirectionRightLeft
    Nigrosome 1 and SNcRightLeftRightLeft
    Times
     112.011.810.612.6
     212.111.411.012.3
     312.311.410.613.0
     411.911.910.412.4
     512.511.010.512.6
     612.311.410.912.4
    SD0.200.320.210.26
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American Journal of Neuroradiology: 41 (1)
American Journal of Neuroradiology
Vol. 41, Issue 1
1 Jan 2020
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Cite this article
N. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo, Y. Shibamoto
Visualization of Nigrosome 1 from the Viewpoint of Anatomic Structure
American Journal of Neuroradiology Jan 2020, 41 (1) 86-91; DOI: 10.3174/ajnr.A6338

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Visualization of Nigrosome 1 from the Viewpoint of Anatomic Structure
N. Arai, H. Kan, M. Ogawa, Y. Uchida, M. Takizawa, K. Omori, T. Miyati, H. Kasai, H. Kunitomo, Y. Shibamoto
American Journal of Neuroradiology Jan 2020, 41 (1) 86-91; DOI: 10.3174/ajnr.A6338
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