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Research ArticleAdult Brain
Open Access

Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease

F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson and J. Kulisevsky
American Journal of Neuroradiology September 2019, 40 (9) 1464-1468; DOI: https://doi.org/10.3174/ajnr.A6168
F. Sampedro
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
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S. Martínez-Horta
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain
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J. Perez-Perez
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain
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A. Horta-Barba
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
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J. Martin-Lahoz
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
fUniversitat Autónoma de Barcelona (S.M.-H., J.P.-P., J.M.-L., B.G.-A., J.K.), Barcelona, Spain
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A. Alonso-Solís
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
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I. Corripio
cPsychiatry Department (I.C.), Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
hCentro de Investigación Biomédica en Red-Salud Mental (I.C.), Madrid, Spain.
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B. Gomez-Anson
bNeuroradiology, Radiology Department (B.G.-A.)
gEuropean Huntington's Disease Network (S.M.-H., J.P.-P., A.H.-B., J.K.), Ulm, Germany
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J. Kulisevsky
aFrom the Movement Disorders Unit (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Neurology Department
dBiomedical Research Institute (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., A.A.-S., I.C., J.K.), Barcelona, Spain
eCentro de Investigación en Red-Enfermedades Neurodegenerativas (F.S., S.M.-H., J.P.-P., A.H.-B., J.M.-L., J.K.), Madrid, Spain
gEuropean Huntington's Disease Network (S.M.-H., J.P.-P., A.H.-B., J.K.), Ulm, Germany
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F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson, J. Kulisevsky
Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease
American Journal of Neuroradiology Sep 2019, 40 (9) 1464-1468; DOI: 10.3174/ajnr.A6168

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Widespread Increased Diffusivity Reveals Early Cortical Degeneration in Huntington Disease
F. Sampedro, S. Martínez-Horta, J. Perez-Perez, A. Horta-Barba, J. Martin-Lahoz, A. Alonso-Solís, I. Corripio, B. Gomez-Anson, J. Kulisevsky
American Journal of Neuroradiology Sep 2019, 40 (9) 1464-1468; DOI: 10.3174/ajnr.A6168
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