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Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery

W. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez and J. C. Lasheras
American Journal of Neuroradiology July 2019, 40 (7) 1242-1249; DOI: https://doi.org/10.3174/ajnr.A6097
W. Coenen
aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
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C. Gutiérrez-Montes
cDepartment of Mechanical and Mining Engineering (C.G.-M., C.M.-B.), University of Jaén, Jaén, Andalucía, Spain
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  • ORCID record for C. Gutiérrez-Montes
S. Sincomb
aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
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E. Criado-Hidalgo
aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
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K. Wei
dMRI Center (K.W., K.K.), Huntington Medical Research Institutes, Pasadena, California
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K. King
dMRI Center (K.W., K.K.), Huntington Medical Research Institutes, Pasadena, California
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V. Haughton
eDepartment of Radiology (V.H.), School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.
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C. Martínez-Bazán
cDepartment of Mechanical and Mining Engineering (C.G.-M., C.M.-B.), University of Jaén, Jaén, Andalucía, Spain
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A.L. Sánchez
aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
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J. C. Lasheras
aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
bBioengineering (J.C.L.), University of California, San Diego, San Diego, California
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Article Information

vol. 40 no. 7 1242-1249
DOI 
https://doi.org/10.3174/ajnr.A6097
PubMed 
31196863

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Received February 22, 2019
  • Accepted after revision May 8, 2019
  • Published online July 8, 2019.

Article Versions

  • Latest version (June 13, 2019 - 07:00).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2019 by American Journal of Neuroradiology

Author Information

  1. W. Coenena,
  2. C. Gutiérrez-Montesc,
  3. S. Sincomba,
  4. E. Criado-Hidalgoa,
  5. K. Weid,
  6. K. Kingd,
  7. V. Haughtone,
  8. C. Martínez-Bazánc,
  9. A.L. Sáncheza and
  10. J. C. Lasherasa,b
  1. aFrom the Departments of Mechanical and Aerospace Engineering (W.C., S.S., E.C.-H., A.L.S., J.C.L.)
  2. bBioengineering (J.C.L.), University of California, San Diego, San Diego, California
  3. cDepartment of Mechanical and Mining Engineering (C.G.-M., C.M.-B.), University of Jaén, Jaén, Andalucía, Spain
  4. dMRI Center (K.W., K.K.), Huntington Medical Research Institutes, Pasadena, California
  5. eDepartment of Radiology (V.H.), School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin.
  1. Please address correspondence to Wilfried Coenen, PhD, Department of Mechanical and Aerospace Engineering, University of California San Diego, 9500 Gilman Dr, No. 0411, La Jolla, CA 92093; e-mail: wicoenen{at}ucsd.edu
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W. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez, J. C. Lasheras
Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery
American Journal of Neuroradiology Jul 2019, 40 (7) 1242-1249; DOI: 10.3174/ajnr.A6097

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Subject-Specific Studies of CSF Bulk Flow Patterns in the Spinal Canal: Implications for the Dispersion of Solute Particles in Intrathecal Drug Delivery
W. Coenen, C. Gutiérrez-Montes, S. Sincomb, E. Criado-Hidalgo, K. Wei, K. King, V. Haughton, C. Martínez-Bazán, A.L. Sánchez, J. C. Lasheras
American Journal of Neuroradiology Jul 2019, 40 (7) 1242-1249; DOI: 10.3174/ajnr.A6097
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