Article Figures & Data
Figures
- Fig 1.
PRISMA flow chart of articles.
- Fig 2.
Endothelialization along the flow-diverting stent. Interplay among the flow-diverting stent, native vessel endothelium, molecular factors at aneurysm dome, and circulating endothelial progenitor cells is depicted in cartoon format. Stromal cell-derived factor 1 (SDF-1) released from the bone marrow binds to the C-X-C chemokine receptor type 4 (CXCR-4) receptor on circulating EPCs and directs homing of these cells to the bone marrow. At the site of flow-diverter placement, circulating EPCs (shown as CD31+ CD34+) are seen along device struts. At the aneurysm dome, several molecules, including matrix metalloproteinase-9 (MMP-9), act to stimulate vascular repair. Ang-1 is furthermore released from the disrupted endothelium, where its prorepair action is mediated by the Tie2 receptor expressed on the vascular endothelium. TGF-β indicates transforming growth factor β. Artist: David Fisher, Dept of Neurosurgery, University of Alabama-Birmingham. Published with permission.
Jump to section
Related Articles
Cited By...
- Evaluation of flow diverters for cerebral aneurysm therapy: recommendations for imaging analyses in clinical studies, endorsed by ESMINT, ESNR, OCIN, SILAN, SNIS, and WFITN
- Threshold ratio of stent-to-vessel diameter related to in-stent stenosis after flow diverter treatment of intracranial aneurysm
- Subacute Stent Deformities as an Underlying Reason for Vessel Stenosis after Flow Diversion with the p64 Stent: Review and Discussion of Biologic Mechanisms and Consequences
- Comparison of flow diverter alone versus flow diverter with coiling for large and giant intracranial aneurysms: systematic review and meta-analysis of observational studies
- Braids and beyond: a comprehensive study on pipeline device braid stability from PREMIER data
- Off-label in-silico flow diverter performance assessment in posterior communicating artery aneurysms
- Initial Experience with the Derivo 2Heal Flow Diverter under Standard or Reduced-Dose Single Antiplatelet Therapy
- Comprehensive Analysis of Post-Pipeline Endothelialization and Remodeling
- Systematic Review and Meta-Analysis of Endovascular Therapy Effectiveness for Unruptured Saccular Intracranial Aneurysms
- Recovery from Cranial Nerve Symptoms after Flow Diversion without Coiling for Unruptured Very Large and Giant ICA Aneurysms