Article Figures & Data
Figures
- Fig 1.
Typical images of a patient without brain metastases derived via automatic segmentation software. A, WM segmentation overlaid on a T2-weighted image, in which the intensity of the light-pink color overlay corresponds to the calculated WM partial volume per voxel. The red line indicates the intracranial volume. Similar images are shown for GM in green (B), CSF in blue (C), non-WM/GM/CSF in yellow (D), and myelin partial volume in yellow and green (E).
- Fig 2.
Comparison of volumetric and myelin measurements derived via quantitative synthetic MR imaging pre- and postadministration of a gadolinium-based contrast agent. Based on the Wilcoxon signed rank test, asterisk = P < .05; double asterisks = P < .01; and triple asterisks = P < .001.
- Fig 3.
Representative quantitative maps of a patient with brain metastasis. T1-weighted image before (A) and after (F) administration of gadolinium-based contrast agent and quantitative maps overlaid on the T1-weighted image before (B–E) and after (G–J) administration of gadolinium-based contrast agents are shown. The brain metastasis shows contrast enhancement (arrows in A and F). The increase in myelin partial volume is clear in the brain metastasis on the myelin partial volume maps (arrows in B and G). The decreases in T1, T2, and proton density are clear in the brain metastasis on the T1 (arrows in C and H), T2 (arrows in D and I), and proton-density (arrows in E and J) maps.
Tables
T1, T2, PD values, and VMY determined via quantitative synthetic MRI pre- and postadministration of gadolinium-based contrast agenta
VMY (%) T1 (ms) T2 (ms) PD (%) With metastases pre-GBCA 21.14 ± 1.83 1061.68 ± 59.80 99.26 ± 12.37 75.90 ± 1.99 With metastases post-GBCA 21.92 ± 1.67 1010.35 ± 54.57 95.59 ± 13.75 74.85 ± 2.02 Difference 0.78 ± 0.85b −51.34 ± 43.44b −2.67 ± 9.35c −1.05 ± 1.26b Without metastases pre-GBCA 20.84 ± 1.08 1076.41 ± 75.40 98.43 ± 13.42 75.87 ± 1.79 Without metastases post-GBCA 21.59 ± 1.01 1029.58 ± 70.97 93.73 ± 15.39 74.59 ± 2.03 Difference 0.75 ± 0.53d −46.84 ± 31.23d −4.70 ± 12.21b −1.28 ± 1.35b
