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Index by author

July 01, 2018; Volume 39,Issue 7

  1. Zhang, Y.

    1. Neurointervention
      Risk of Branch Occlusion and Ischemic Complications with the Pipeline Embolization Device in the Treatment of Posterior Circulation Aneurysms
      N. Adeeb, C.J. Griessenauer, A.A. Dmytriw, H. Shallwani, R. Gupta, P.M. Foreman, H. Shakir, J. Moore, N. Limbucci, S. Mangiafico, A. Kumar, C. Michelozzi, Y. Zhang, V.M. Pereira, C.C. Matouk, M.R. Harrigan, A.H. Siddiqui, E.I. Levy, L. Renieri, T.R. Marotta, C. Cognard, C.S. Ogilvy and A.J. Thomas
      American Journal of Neuroradiology July 2018, 39 (7) 1303-1309; DOI: https://doi.org/10.3174/ajnr.A5696

  2. Zhao, Y.

    1. EDITOR'S CHOICEAdult Brain
      Relationship between Cough-Associated Changes in CSF Flow and Disease Severity in Chiari I Malformation: An Exploratory Study Using Real-Time MRI
      A.F. Bezuidenhout, D. Khatami, C.B. Heilman, E.M. Kasper, S. Patz, N. Madan, Y. Zhao and R.A. Bhadelia
      American Journal of Neuroradiology July 2018, 39 (7) 1267-1272; DOI: https://doi.org/10.3174/ajnr.A5670

      The authors correlated disease severity in symptomatic patients with Chiari I malformation with cough-associated changes in CSF flow as measured with real-time MR imaging. Patients were classified into 2 groups by neurosurgeons blinded to MR imaging measurements: 1) nonspecific Chiari I malformation (5/13)—Chiari I malformation with nonspecific symptoms like non-cough-related or mild occasional cough-related headache, neck pain, dizziness, paresthesias, and/or trouble swallowing; 2) specific Chiari I malformation (8/13)—patients with Chiari I malformation with specific symptoms and/or objective findings like severe cough-related headache, myelopathy, syringomyelia, and muscle atrophy. There was a significant negative correlation between the percentage change in CSF stroke volume (resting to post coughing) and Chiari I malformation disease severity. They conclude that assessment of CSF flow response to a coughing challenge has the potential to become a valuable objective noninvasive test for clinical assessment of disease severity in patients with Chiari I malformation.

  3. Zhu, C.

    1. FELLOWS' JOURNAL CLUBAdult Brain
      Open Access
      Clinical Significance of Intraplaque Hemorrhage in Low- and High-Grade Basilar Artery Stenosis on High-Resolution MRI
      C. Zhu, X. Tian, A.J. Degnan, Z. Shi, X. Zhang, L. Chen, Z. Teng, D. Saloner, J. Lu and Q. Liu
      American Journal of Neuroradiology July 2018, 39 (7) 1286-1292; DOI: https://doi.org/10.3174/ajnr.A5676

      Patients with basilar artery stenosis (n=126; 66 symptomatic and 60 asymptomatic) underwent high-resolution MR imaging. The relationship between imaging findings (intraplaque hemorrhage, contrast enhancement, degree of stenosis, minimal lumen area, and plaque burden) and symptoms was analyzed. Intraplaque hemorrhage was identified in 22 patients (17.5%), including 21 (31.8%) symptomatic patients and 1 (1.7%) asymptomatic patient. Multivariate analysis showed that intraplaque hemorrhage was the strongest independent marker of symptomatic status. Contrast enhancement was also independently associated with symptomatic status. The authors conclude that intraplaque hemorrhage is present in both low- and high-grade stenotic basilar artery plaques and is independently associated with symptomatic stroke status. Intraplaque hemorrhage may identify high-risk plaque and provide new insight into the management of patients with stroke without significant stenosis.

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