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Research Article

Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke

From the American Association of Neurological Surgeons (AANS), American Society of Neuroradiology (ASNR), Cardiovascular and Interventional Radiology Society of Europe (CIRSE), Canadian Interventional Radiology Association (CIRA), Congress of Neurological Surgeons (CNS), European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), European Stroke Organization (ESO), Society for Cardiovascular Angiography and Interventions (SCAI), Society of Interventional Radiology (SIR), Society of NeuroInterventional Surgery (SNIS), and World Stroke Organization (WSO), D. Sacks, B. Baxter, B.C.V. Campbell, J.S. Carpenter, C. Cognard, D. Dippel, M. Eesa, U. Fischer, K. Hausegger, J.A. Hirsch, M.S. Hussain, O. Jansen, M.V. Jayaraman, A.A. Khalessi, B.W. Kluck, S. Lavine, P.M. Meyers, S. Ramee, D.A. Rüfenacht, C.M. Schirmer and D. Vorwerk
American Journal of Neuroradiology June 2018, 39 (6) E61-E76; DOI: https://doi.org/10.3174/ajnr.A5638
aFrom the Department of Interventional Radiology (D.S.), The Reading Hospital and Medical Center, West Reading, Pennsylvania
D. Sacks
aFrom the Department of Interventional Radiology (D.S.), The Reading Hospital and Medical Center, West Reading, Pennsylvania
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B. Baxter
bDepartment of Radiology (B.B.), Erlanger Medical Center, Chattanooga, Tennessee
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B.C.V. Campbell
cDepartments of Medicine and Neurology (B.C.V.C.), Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia
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J.S. Carpenter
dDepartment of Radiology (J.S.C.), West Virginia University, Morgantown, West Virginia
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C. Cognard
eDepartment of Diagnostic and Therapeutic Neuroradiology (C.C.), Centre Hospitalier Universitaire de Toulouse, Hôpital Purpan, Toulouse, France
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D. Dippel
fDepartment of Neurology (D.D.), Erasmus University Medical Center, Rotterdam, the Netherlands
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M. Eesa
gDepartment of Radiology (M.E.), University of Calgary, Calgary, Alberta, Canada
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U. Fischer
hDepartment of Neurology (U.F.), Inselspital-Universitätsspital Bern, Bern, Switzerland
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K. Hausegger
iDepartment of Radiology (K.H.), Klagenfurt State Hospital, Klagenfurt am Wörthersee, Austria
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J.A. Hirsch
jNeuroendovascular Program, Department of Radiology (J.A.H.), Massachusetts General Hospital, Boston, Massachusetts
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M.S. Hussain
kCerebrovascular Center, Neurological Institute (M.S.H.), Cleveland Clinic, Cleveland, Ohio
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O. Jansen
lDepartment of Radiology and Neuroradiology (O.J.), Klinik für Radiologie und Neuroradiologie, Kiel, Germany
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M.V. Jayaraman
mDepartments of Diagnostic Imaging, Neurology, and Neurosurgery (M.V.J.), Warren Alpert School of Medicine at Brown University, Rhode Island Hospital, Providence, Rhode Island
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A.A. Khalessi
nDepartment of Surgery (A.A.K.), University of California San Diego Health, San Diego, California
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B.W. Kluck
oInterventional Cardiology (B.W.K.), Heart Care Group, Allentown, Pennsylvania
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S. Lavine
pDepartments of Neurological Surgery and Radiology (S.L.), Columbia University Medical Center/New York–Presbyterian Hospital, New York, New York
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P.M. Meyers
qDepartments of Radiology and Neurological Surgery (P.M.M.), Columbia University College of Physicians and Surgeons, New York, New York
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S. Ramee
rInterventional Cardiology, Heart and Vascular Institute (S.R.), Ochsner Medical Center, New Orleans, Louisiana
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D.A. Rüfenacht
sNeuroradiology Division (D.A.R.), Swiss Neuro Institute–Clinic Hirslanden, Zürich, Switzerland
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C.M. Schirmer
tDepartment of Neurosurgery and Neuroscience Center (C.M.S.), Geisinger Health System, Wilkes-Barre, Pennsylvania
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D. Vorwerk
uDiagnostic and Interventional Radiology Institutes (D.V.), Klinikum Ingolstadt, Ingolstadt, Germany.
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  • Article
  • Figures & Data
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Article Figures & Data

Tables

    • View popup
    Table 1:

    mTICI revascularization scale scores30,31,113

    ScoreDescription
    0No perfusion, complete obstruction; no flow past occlusion of “major” vessel
    1Perfusion past initial obstruction but limited distal branch filling with little/slow distal perfusion
    2aPartial perfusion: <50% of “major” vascular territory perfused (eg, filling and complete perfusion through one M2 division)
    2bPartial perfusion: ≥50% of major vascular territory is filled, but there is not complete and normal perfusion of entire territory
    3Complete or full perfusion with filling of all distal branches
    • Note:—mTICI indicates modified thrombolysis in cerebral infarction.

    • View popup
    Table 2:

    mRS Scores35

    ScoreDescription
    0No symptoms
    1No significant disability: able to carry out all usual activities despite some symptoms
    2Slight disability: able to look after own affairs without assistance but unable to carry out all previous activities
    3Moderate disability: requires some help but able to walk unassisted
    4Moderately severe disability: unable to attend to own bodily needs without assistance and unable to walk unassisted
    5Severe disability: requires constant nursing care and attention, bedridden, incontinent
    6Dead
    • Note:—mRS indicates modified Rankin Scale.

    • View popup
    Table 3:

    Endovascular therapy quality improvement case review triggers and process metrics

    Indications for Endovascular Treatment
    • Metric 1: At least 90% of patients who meet the institution selection criteria (indications/contraindications) should be treated with endovascular therapy.

    Data Collection
    • Metric 2: 100% of patients have the required minimum process and outcomes data entered into an institutional or national data base, trial, or registry.

    Key Time Intervals
    Door to imaging
    • Metric 3: 75% of patients being evaluated for revascularization should have imaging initiated within 30 minutes from time of arrival. At the best of centers with high volumes and an established resource infrastructure, this is expected to be achieved in 12 minutes.

    Imaging to puncture
    • Metric 4: 75% of patients treated with endovascular therapy should have an imaging-to-puncture time of 110 minutes or less. At the best of centers with high volumes and an established resource infrastructure, this is expected to be achieved in 50 minutes or less.

    • Metric 5: For patients transferred from another site and in whom imaging is not repeated, 75% of patients being treated should have a door-to-puncture time of 80 minutes or less.

    Puncture to revascularization
    • Metric 6: In 70% of patients, mTICI score ≥2b should be reached ideally within 60 minutes of arterial puncture.

    Outcome Metrics
    Recanalization/reperfusion
    • Metric 7: The mTICI scale should be the primary scale used to assess angiographic reperfusion.

    • Metric 8: At least 70% of patients should have an mTICI score ≥2b/3 (>50% reperfusion) for all clot locations.

    Postprocedure CT/MR Imaging
    • Metric 9: At least 90% of patients should have a brain CT or MR imaging within 36 hours of the end of the procedure.

    SICH
    • Metric 10: 100% of cases with SICH are reviewed.

    • Metric 11: No more than 10% of treated patients should develop SICH.

    Embolization of new territory
    • Metric 12: No more than 10% of patients should have embolization of new territory.

    Death within 72 hours of treatment
    • Metric 13: 100% of cases of death within 72 hours of the end of the procedure are reviewed.

    Clinical Outcomes
    • Metric 14: All treated patients have a documented NIHSS score at discharge. Attempts are made to contact and document a follow-up mRS score at 90 days (evaluated in person or via telephone) on all treated patients. At least 90% of treated patients have a documented 90-day mRS score.

    • Metric 15: Of all treated patients, at least 30% are independent (ie, mRS score 0–2) at 90 days after treatment.

    • Note:—mRS indicates modified Rankin Scale; mTICI, modified thrombolysis in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; SICH, symptomatic intracranial hemorrhage.

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American Journal of Neuroradiology: 39 (6)
American Journal of Neuroradiology
Vol. 39, Issue 6
1 Jun 2018
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From the American Association of Neurological Surgeons (AANS), American Society of Neuroradiology (ASNR), Cardiovascular and Interventional Radiology Society of Europe (CIRSE), Canadian Interventional Radiology Association (CIRA), Congress of Neurological Surgeons (CNS), European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), European Stroke Organization (ESO), Society for Cardiovascular Angiography and Interventions (SCAI), Society of Interventional Radiology (SIR), Society of NeuroInterventional Surgery (SNIS), and World Stroke Organization (WSO), D. Sacks, B. Baxter, B.C.V. Campbell, J.S. Carpenter, C. Cognard, D. Dippel, M. Eesa, U. Fischer, K. Hausegger, J.A. Hirsch, M.S. Hussain, O. Jansen, M.V. Jayaraman, A.A. Khalessi, B.W. Kluck, S. Lavine, P.M. Meyers, S. Ramee, D.A. Rüfenacht, C.M. Schirmer, D. Vorwerk
Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke
American Journal of Neuroradiology Jun 2018, 39 (6) E61-E76; DOI: 10.3174/ajnr.A5638

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Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke
From the American Association of Neurological Surgeons (AANS), American Society of Neuroradiology (ASNR), Cardiovascular and Interventional Radiology Society of Europe (CIRSE), Canadian Interventional Radiology Association (CIRA), Congress of Neurological Surgeons (CNS), European Society of Minimally Invasive Neurological Therapy (ESMINT), European Society of Neuroradiology (ESNR), European Stroke Organization (ESO), Society for Cardiovascular Angiography and Interventions (SCAI), Society of Interventional Radiology (SIR), Society of NeuroInterventional Surgery (SNIS), and World Stroke Organization (WSO), D. Sacks, B. Baxter, B.C.V. Campbell, J.S. Carpenter, C. Cognard, D. Dippel, M. Eesa, U. Fischer, K. Hausegger, J.A. Hirsch, M.S. Hussain, O. Jansen, M.V. Jayaraman, A.A. Khalessi, B.W. Kluck, S. Lavine, P.M. Meyers, S. Ramee, D.A. Rüfenacht, C.M. Schirmer, D. Vorwerk
American Journal of Neuroradiology Jun 2018, 39 (6) E61-E76; DOI: 10.3174/ajnr.A5638
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