Article Figures & Data
Figures
- Fig 1.
An example of the cord surface estimation obtained using the active surface method. The upper left image shows the location of the landmarks (red markers) that can be visualized in this sagittal slice. These landmarks were manually placed in the axial slices at the center area of the cord with a distance between them of approximately 10 mm. The upper right image shows the cord outline estimation (red lines). The lower axial slices show some examples of the spinal cord segmentation obtained (region within red contour).
- Fig 2.
Box-and-whisker plots of normalized cross-sectional areas: NMCSA (upper left), NCSA23 (upper right), NCSA34 (lower left), and NCSA45 (lower right).
Tables
Patients with MS Median age (range) (yr) 51 (33–61) Men/women 19:12 Mean disease duration at baseline (range) (yr) 11.74 (2–33) Median EDSS score at baseline (range) 5.5 (3.0–6.5) Mean brain T2LV at baseline (SD) (mL) 18.12 (20.63) Mean brain T1LV at baseline (SD) (mL) 7.41 (8.47) Mean BPF at baseline (SD) 73.13% (5.86%) Baseline 2 Years 14 Years Median EDSS score (range) 5.5 (3.0–6.5) 6.0 (4.0–8.5) 7.5 (4.0–9.5) Follow-Up Mean brain T2LV (SD) (mL) 21.56 (20.65) Mean brain T1LV (SD) (mL) 9.53 (9.32) Mean BPF (SD) 70.33% (5.84%) NMCSA NCSA23 NCSA34 NCSA45 Mean at baseline (SD) (mm2) 71.49 (6.37) 67.76 (7.26) 68.21 (7.39) 71.51 (8.27) Mean at follow-up (SD) (mm2) 68.12 (8.91) 65.40 (10.27) 65.23 (10.61) 67.95 (9.97) Cord area change averaged by year (SD) (%) −0.77 (1.14) −0.62 (1.20) −0.74 (1.47) −0.77 (1.61) P value .001 .006 .009 .006
