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Nine patients with suspected elevated intracranial pressure and 9 healthy control patients were included in this prospective study. Control patients underwent DENSE MR imaging through the midsagittal brain while patients underwent DENSE MR imaging followed immediately by lumbar puncture with opening pressure measurement, CSF removal, closing pressure measurement, and immediate repeat DENSE MR imaging. All patients had elevated opening pressure (median, 36.0 cm water), decreased by the removal of CSF to a median closing pressure of 17.0 cm water. Measured CSF pressure in patients pre= and post=lumbar puncture correlated significantly with pontine displacement. The authors conclude that DENSE MR imaging may providing a method to noninvasively assess intracranial pressure status in idiopathic intracranial hypertension.