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Letter

LAST2 CH2ANCE: A Summary of Selection Criteria for Thrombectomy in Acute Ischemic Stroke

P. Yang, Y. Zhang and J. Liu
American Journal of Neuroradiology September 2017, 38 (9) E58-E59; DOI: https://doi.org/10.3174/ajnr.A5249
P. Yang
aDepartment of Neurosurgery Changhai Hospital Second Military Medical University Shanghai, China
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Y. Zhang
aDepartment of Neurosurgery Changhai Hospital Second Military Medical University Shanghai, China
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J. Liu
aDepartment of Neurosurgery Changhai Hospital Second Military Medical University Shanghai, China
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In 2015 and 2016, six randomized controlled trials (MR CLEAN, ESCAPE, SWIFT PRIME, REVASCAT, EXTEND-IA, and THRACE), which focused on the endovascular treatment of patients with acute ischemic stroke caused by large vessel occlusion, were published in The New England Journal of Medicine1 and Lancet Neurology.2 All of these trials favor thrombectomy for patients with acute ischemic stroke with large vessel occlusion, which can significantly improve patients' 90-day outcomes. The impact of these trials is huge. Cerebrovascular physicians all over the world have started putting more efforts on thrombectomy. However, there are many indications and contraindications for thrombectomy, which are a challenge for the physician to remember and may cause potential errors and delays in the process of selecting candidates.

To handle this problem, we carefully reviewed the literature and guidelines3,4 and summarized the indications and contraindications as “LAST2 CH2ANCE,” which represents different aspects of patient selection. The details of “LAST2 CH2ANCE” are shown in the Table.

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Details of LAST2 CH2ANCE

We have used this to do many training sessions in China. During the posttraining survey, most physicians were impressed by this summary. They can remember complex patient selection criteria in a few minutes even though they knew very little before the training. Therefore, we feel it is better to let the entire community know this system to make rapid and accurate patient selection for thrombectomy. Because thrombectomy is the last chance for patients with acute ischemic stroke with large vessel occlusion to recover, we hope this patient selection summary, “LAST2 CH2ANCE,” will be helpful.

References

  1. 1.↵
    1. Goyal M,
    2. Menon BK,
    3. van Zwam WH, et al
    . Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet 2016;387:1723–31 doi:10.1016/S0140-6736(16)00163-X pmid:26898852
    CrossRefPubMed
  2. 2.↵
    1. Bracard S,
    2. Ducrocq X,
    3. Mas JL, et al
    . Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial. Lancet Neurol 2016;15:1138–47 doi:10.1016/S1474-4422(16)30177-6 pmid:27567239
    CrossRefPubMed
  3. 3.↵
    1. Fransen PS,
    2. Beumer D,
    3. Berkhemer OA, et al
    . MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial. Trials 2014;15:343 doi:10.1186/1745-6215-15-343 pmid:25179366
    CrossRefPubMed
  4. 4.↵
    1. Powers WJ,
    2. Derdeyn CP,
    3. Biller J, et al
    . 2015 American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015;46:3020–35 doi:10.1161/STR.0000000000000074 pmid:26123479
    Abstract/FREE Full Text
  • © 2017 by American Journal of Neuroradiology
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American Journal of Neuroradiology: 38 (9)
American Journal of Neuroradiology
Vol. 38, Issue 9
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P. Yang, Y. Zhang, J. Liu
LAST2 CH2ANCE: A Summary of Selection Criteria for Thrombectomy in Acute Ischemic Stroke
American Journal of Neuroradiology Sep 2017, 38 (9) E58-E59; DOI: 10.3174/ajnr.A5249

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LAST2 CH2ANCE: A Summary of Selection Criteria for Thrombectomy in Acute Ischemic Stroke
P. Yang, Y. Zhang, J. Liu
American Journal of Neuroradiology Sep 2017, 38 (9) E58-E59; DOI: 10.3174/ajnr.A5249
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