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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleINTERVENTIONAL

Acute Basilar Artery Occlusion: Differences in Characteristics and Outcomes after Endovascular Therapy between Patients with and without Underlying Severe Atherosclerotic Stenosis

Y.Y. Lee, W. Yoon, S.K. Kim, B.H. Baek, G.S. Kim, J.T. Kim and M.S. Park
American Journal of Neuroradiology August 2017, 38 (8) 1600-1604; DOI: https://doi.org/10.3174/ajnr.A5233
Y.Y. Lee
aFrom the Departments of Radiology (Y.Y.L., W.Y., S.K.K., B.H.B., G.S.K.)
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  • ORCID record for Y.Y. Lee
W. Yoon
aFrom the Departments of Radiology (Y.Y.L., W.Y., S.K.K., B.H.B., G.S.K.)
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S.K. Kim
aFrom the Departments of Radiology (Y.Y.L., W.Y., S.K.K., B.H.B., G.S.K.)
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B.H. Baek
aFrom the Departments of Radiology (Y.Y.L., W.Y., S.K.K., B.H.B., G.S.K.)
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G.S. Kim
aFrom the Departments of Radiology (Y.Y.L., W.Y., S.K.K., B.H.B., G.S.K.)
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J.T. Kim
bNeurology (J.T.K., M.S.P.), Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Republic of Korea.
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M.S. Park
bNeurology (J.T.K., M.S.P.), Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Republic of Korea.
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    Fig 1.

    A 74-year-old male patient with acute stroke due to acute basilar artery occlusion. A, Left vertebral artery angiogram shows an occlusion (arrow) at the proximal segment of the basilar artery. B, Angiogrm obtained after 1 passage of the stent retriever reveals a severe underlying atherosclerotic stenosis (arrow) at the proximal segment of the basilar artery. C, Left vertebral angiogram obtained after intracranial angioplasty and stent placement shows complete recanalization of the basilar artery with good distal perfusion. Arrows indicate the proximal and distal ends of the Wingspan stent. D, Photograph shows small fragmented thrombi retrieved with a Solitaire stent.

Tables

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    Table 1:

    Baseline characteristics of the study population

    All Patients (n = 62)Patients with ICAS (n = 15)Patients without ICAS (n = 47)P Value
    Age (mean) (yr)69.6 ± 11.9567.1 ± 10.0370.3 ± 12.50.205
    Male sex (No.) (%)36 (58.1)12 (80.0)24 (51.1).048
    Risk factor (No.) (%)
        Hypertension37 (59.7)11 (73.3)26 (55.3).216
        Diabetes mellitus14 (22.6)4 (26.7)10 (21.3).727
        Dyslipidemia16 (25.8)6 (40.0)10 (21.3).182
        Smoking15 (24.2)5 (33.3)10 (21.3).489
        Coronary artery disease5 (8.1)0 (0.0)5 (10.6).323
    IV thrombolysis (No.) (%)17 (27.4)7 (46.7)10 (21.3).094
    Occlusion sites (No.) (%)
        Proximal12 (19.4)9 (60.0)3 (6.4)<.001
        Middle3 (4.8)2 (13.3)1 (2.1).143
        Distal47 (75.8)4 (26.7)43 (91.5)<.001
    Bilateral thalamic infarction (No.) (%)13 (21.0)0 (0.0)13 (27.7).027
    Baseline NIHSS score (mean)12.4 ± 6.2312.7 ± 5.9512.3 ± 6.37.773
    pc-ASPECTS (median) (IQR)7 (6–8)7 (6–8)7 (6–8).794
    Time to procedure (mean) (min)289.6 ± 129.68309.3 ± 139.65283.3 ± 127.60.532
    Procedure time (mean) (min)30.9 ± 17.7639.0 ± 19.4728.3 ± 16.56.006
    Time to revascularization (mean) (min)321.0 ± 136.22348.3 ± 143.84312.2 ± 134.12.459
    • Note:—IQR indicates interquartile range; pc-ASPECTS, posterior circulation ASPECTS.

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    Table 2:

    Outcomes after endovascular therapy in 62 patients with acute stroke due to BAO

    All Patients (n = 62)Patients with ICAS (n = 15)Patients without ICAS (n = 47)P Value
    mTICI 2b or 3 (No.) (%)60 (96.8)15 (100.0)45 (95.7)NS
    mRS 0–2 (No.) (%)33 (53.2)9 (60.0)24 (51.1)NS
    Symptomatic hemorrhage (No.) (%)1 (1.6)0 (0.0)1 (2.1)NS
    Mortality (No.) (%)10 (16.1)2 (13.3)8 (17.0)NS
    • Note:—mTICI indicates modified TICI; NS, nonsignificant.

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American Journal of Neuroradiology: 38 (8)
American Journal of Neuroradiology
Vol. 38, Issue 8
1 Aug 2017
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Y.Y. Lee, W. Yoon, S.K. Kim, B.H. Baek, G.S. Kim, J.T. Kim, M.S. Park
Acute Basilar Artery Occlusion: Differences in Characteristics and Outcomes after Endovascular Therapy between Patients with and without Underlying Severe Atherosclerotic Stenosis
American Journal of Neuroradiology Aug 2017, 38 (8) 1600-1604; DOI: 10.3174/ajnr.A5233

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Acute Basilar Artery Occlusion: Differences in Characteristics and Outcomes after Endovascular Therapy between Patients with and without Underlying Severe Atherosclerotic Stenosis
Y.Y. Lee, W. Yoon, S.K. Kim, B.H. Baek, G.S. Kim, J.T. Kim, M.S. Park
American Journal of Neuroradiology Aug 2017, 38 (8) 1600-1604; DOI: 10.3174/ajnr.A5233
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  • Rescue intracranial stenting for failed mechanical thrombectomy of vertebrobasilar occlusions: a pooled analysis from the French and German national stroke registries
  • Mechanical thrombectomy in basilar artery occlusions: impact of first-line strategy as a function of the occlusion level
  • Clinical outcomes of reperfusion therapy in patients with site-specific basilar artery occlusion
  • Rescue intracranial stenting for failed posterior circulation thrombectomy: analysis from the Stenting and Angioplasty in NeuroThrombectomy (SAINT) study
  • Interobserver Agreement in Scoring Angiographic Results of Basilar Artery Occlusion Stroke Therapy
  • Choice of ANaesthesia for EndoVAScular treatment of acute ischaemic stroke at posterior circulation (CANVAS II): protocol for an exploratory randomised controlled study
  • Significance of angiographic clot meniscus sign in mechanical thrombectomy of basilar artery stroke
  • Stroke mechanisms and outcomes of isolated symptomatic basilar artery stenosis
  • Current endovascular strategies for posterior circulation large vessel occlusion stroke: report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee
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  • Safety, Efficacy, and Durability of Stent-Assisted Coiling Treatment of M2 (Insular) Segment MCA Aneurysms
  • Endovascular Management of Intracranial Dural AVFs: Transvenous Approach
  • A Meta-analysis of Combined Aspiration Catheter and Stent Retriever versus Stent Retriever Alone for Large-Vessel Occlusion Ischemic Stroke
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