Article Figures & Data
Figures
- Fig 1.
ROI analyzed for apparent diffusion coefficient. ROI placement example. A, 1, 2 = frontal lobe; 3, 4 = parietal lobe. B, 5, 6 = basal ganglia. C, 7, 8 = thalami. D, 9, 10 = temporal lobe; 11, 12 = occipital lobe. E, 13 = pons. F, 14, 15 = cerebellum.
- Fig 2.
Comparison between ADC values (in millions) of different brain regions from CMV-infected fetuses (gray) and a control group (black). A significant difference is shown with an asterisk.
- Fig 3.
Vineland domains and subdomain absolute results distribution by category of the CMV-infected group (gray) compared with the normal expected distribution (black). Only significant results are shown.
- Fig 4.
Correlation between ADC values (in millions) by brain regions and Vineland results by domains or subdomains of neonatal CMV-infected children, including only children without hearing disabilities and Vineland results. Only significant results are shown. BG indicates basal ganglia; Avg., average.
Tables
Controls CMV Group No. (feMRI) 68 90 Maternal age (mean) (yr) 32.05 ± 4.43 31.58 ± 4.23 GA (MRI) (mean) 31.8 ± 2.3 33.1 ± 2.0 GA (infection, No.) NA 1st trimester 25 2nd trimester 43 3rd trimester 15 Unknown 7 VABS–II NA 58 Child's age (mean) (mo) 60.12 ± 30.774 Male (No.) 32 Mean age (mo) 50.75 ± 26.3 Female (No.) 26 Mean age (mo) 71.65 ± 32.4 Hearing disabilities (No.) 8 (14%) Note:—GA indicates gestational age; NA, not applicable.
Region Controls ± SD CMV Group ± SD P Value Frontal lobe 1762.3 ± 191.6 1675.0 ± 190.3 .005 Parietal lobe 1733.9 ± 228.9 1637.2 ± 220.5 .008 Occipital lobe 1700.2 ± 193.7 1629.9 ± 186.7 .022 Temporal lobe 1687.5 ± 172.5 1636.7 ± 159.1 .057 Basal ganglia 1448.5 ± 212.3 1375.2 ± 147.3 .016 Thalamus 1354.2 ± 220.7 1247.2 ± 155.3 <.001 Cerebellum 1486.3 ± 198.7 1407.5 ± 152.5 .005 Pons 1359.2 ± 189.3 1286.3 ± 164.7 .011 ↵a Data are means. ADC units are 106 mm2/s.
