Article Figures & Data
Figures
- Fig 1.
The boxplots for DTI metrics with statistical significance: p (A), q (B), L (C), and ADC (D) values of the enhancing areas and normal-appearing white matter in TDL and HGG, respectively.
- Fig 2.
ROC curve for the diffusion tensor metrics: rCBV, combined ROC of DTI metrics and DSC perfusion, and combined ROC of enhancement pattern with DTI metrics and DSC perfusion.
Tables
Conventional Analysis High-Grade Glioma Not High-Grade Glioma Diagnosed positive 17 6 Diagnosed negative 4 8 Enhancing Areas Perilesional Hyperintensity NAWM Pa Pb 95% CI ADCc TDLs 0.83 ± 0.15 1.56 ± 0.11 0.76 ± 0.06 .02d .81 0.74–0.92 High-grade gliomas 1.01 ± 0.25 1.54 ± 0.2 0.79 ± 0.06 0.90–1.13 pc TDLs 1.44 ± 0.26 2.7 ± 0.19 1.31 ± 0.10 .02d .81 1.29–1.59 High-grade gliomas 1.76 ± 0.44 2.67 ± 0.34 1.37 ± 0.11 1.56–1.96 qc TDLs 0.25 ± 0.07 0.36 ± 0.05 0.55 ± 0.06 .004d .55 0.21–0.30 High-grade gliomas 0.33 ± 0.07 0.38 ± 0.07 0.54 ± 0.07 0.30–0.37 Lc TDLs 1.46 ± 0.26 2.7 ± 0.18 1.43 ± 0.11 .016d .83 1.31–1.62 High-grade gliomas 1.79 ± 0.43 2.7 ± 0.34 1.46 ± 0.09 1.60–1.99 FA TDLs 0.21 ± 0.06 0.44 ± 0.33 0.47 ± 0.07 .341 .052 0.17–0.25 High-grade gliomas 0.23 ± 0.06 0.51 ± 0.09 0.45 ± 0.06 0.20–0.27 rCBV TDLs 2.11 ± 1.12 – .003d 1.47–2.76 High-grade gliomas 3.77 ± 1.65 – 3.02–4.52 - Table 3:
ROC curve results on sensitivity and specificity to differentiate high-grade gliomas and TDLs
Parameter Sensitivity (%) Specificity (%) AUC ADC valuea 52.4 92.9 0.738 p valuea 61.9 85.7 0.738 q valuea 71.4 92.9 0.823 L valuea 76.2 78.6 0.765 rCBV 52.4 92.9 0.796 DTI + DSC perfusion (combined) 71.4 92.9 0.901 Heterogeneous enhancement pattern + combined 85.7 92.9 0.966 ↵a Values of ADC, p, q, and L are in the units of 10−3 mm2/s.
