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Research ArticleSpine Imaging and Spine Image-Guided Interventions

Advantages of 70-kV CT Angiography for the Visualization of the Adamkiewicz Artery: Comparison with 120-kV Imaging

S. Shimoyama, T. Nishii, Y. Watanabe, A.K. Kono, K. Kagawa, S. Takahashi and K. Sugimura
American Journal of Neuroradiology December 2017, 38 (12) 2399-2405; DOI: https://doi.org/10.3174/ajnr.A5372
S. Shimoyama
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
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T. Nishii
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
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Y. Watanabe
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
bDepartment of Radiology (Y.W., A.K.K.), National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
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A.K. Kono
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
bDepartment of Radiology (Y.W., A.K.K.), National Cerebral and Cardiovascular Center, Suita, Osaka, Japan
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K. Kagawa
cDivision of Radiology (K.K.), Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Hyogo, Japan.
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S. Takahashi
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
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K. Sugimura
aFrom the Department of Radiology (S.S., T.N., Y.W., A.K.K., S.T., K.S.), Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
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    Fig 1.

    The AKA was identified according to the following stepwise approach: 1) detect the hairpin vessel; 2) assess the continuity of the vessel to the aorta mainly around the pedicle of the vertebral arch (white arrows) as definite (a), conceivable (b), equivocal (c), or undetectable; 3) check the washout from the early-to-late arterial phase (white arrowhead), because vessels that are more prominent in the late arterial phase are likely to be veins (black arrowhead); and 4) sum the scores. We defined positive identification of the AKA as a total score of ≥3.

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    Fig 2.

    The ROIs placed for measuring CT numbers are shown in a coronal image of the ASA (A), a sagittal image of the ASA (B), an axial image of the spinal cord (C), and a sagittal image of the vertebral bone cortex around the vertebral foramen at the AKA (white arrow) running level (D).

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    Fig 3.

    Box range shows the first and third quartiles; whisker range, from the 5th to 95th percentiles. Seventy-kilovolt CTA yields significantly lower SSDE (A) and dose-length product (B) than 120-kV CTA (P < .001 for both).

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    Fig 4.

    Distribution of the side and level of the CSA to the AKA is shown. Two cases in which the CSA and the AKA were supplied by the axillary artery were described as “other.”

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    Fig 5.

    Seventy-kilovolt CTA yielded significantly higher scores than 120-kV CTA. A, Continuity score, median 3 (interquartile range, 2–3) compared with 2 (interquartile range, 1–3), respectively. B, Total score, median 5 (interquartile range, 4–5), compared with 4 (interquartile range, 3–5), respectively (P < .05 for both).

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    Fig 6.

    A, Curved multiplanar reformatted image of a 77-year-old woman scanned with a 120-kV protocol shows definite continuity between the AKA and the segmental artery. B, Curved multiplanar reformatted image of a 68-year-old man scanned with a 70-kV protocol shows clearer visualization of the AKA and the segmental artery from the aorta. Window center and width were set at 200 and 800.

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    Fig 7.

    Seventy-kilovolt CTA yielded a significantly higher CT number (A) and SNRAorta (B) than 120-kV CTA (P < .001 for both analyses).

Tables

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    Table 1:

    Subject demographic and clinical characteristics

    Variables120-kV (n = 60)70-kV (n = 60)P Value
    Age (yr).81
        Mean6969
        Range57.0–76.354.8–76.0
    Sex.83
        Male (No.)4445
        Female (No.)1615
    Mean body mass index (kg/m2)23.7 ± 3.323.2 ± 3.6.48
    Aortic disorder.46
        Aneurysm (No.)3531
        Dissection (No.)2529
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    Table 2.

    Results of consensus interpretation of the critical segmental artery

    Variables120-kV70-kVP Value
    Detection of collateral pathway (No.) (%)13 (21.7)13 (21.7)1.00
    Detection of critical segmental artery (No.) (%)50 (83.3)54 (90.0).28
    • View popup
    Table 3:

    Accuracy of interpretation of the critical segmental artery

    Variables120-kV70-kVP Value
    Accuracy in all subjects
        Observer A83.395.0.035a
        Observer B83.393.3.084
    Accuracy in subjects with a collateral pathway
        Observer A61.5100.004a
        Observer B30.869.2.047a
    • ↵a Statistically significant.

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    Table 4:

    Results of quantitative image-quality analysisa

    Variables120-kV70-kVP Value
    Spinal cord
        CT number (HU)39.4 ± 7.154.3 ± 11.6<.001b
        SD (HU)12.5 ± 3.413.7 ± 3.9.059
    Bone cortex around the vertebral foramen
        CT number (HU)657.4 ± 134.01,106.1 ± 246.2<.001b
    Anterior spinal artery
        CT number (HU)78.7 ± 13.3127.7 ± 30.0<.001b
        CNRASA-Cord3.4 ± 1.65.6 ± 2.5<.001b
        CNRASA-Bone50.3 ± 17.075.9 ± 30.5<.001b
    • Note:—CNRASA-Cord indicates contrast-to-noise ratio of the anterior spinal artery to the spinal cord; CNRASA-Bone, contrast-to-noise ratio of the anterior spinal artery to bone cortex around the vertebral foramen.

    • ↵a Data are presented as the mean ± SD.

    • ↵b Statistically significant.

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American Journal of Neuroradiology: 38 (12)
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1 Dec 2017
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S. Shimoyama, T. Nishii, Y. Watanabe, A.K. Kono, K. Kagawa, S. Takahashi, K. Sugimura
Advantages of 70-kV CT Angiography for the Visualization of the Adamkiewicz Artery: Comparison with 120-kV Imaging
American Journal of Neuroradiology Dec 2017, 38 (12) 2399-2405; DOI: 10.3174/ajnr.A5372

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Advantages of 70-kV CT Angiography for the Visualization of the Adamkiewicz Artery: Comparison with 120-kV Imaging
S. Shimoyama, T. Nishii, Y. Watanabe, A.K. Kono, K. Kagawa, S. Takahashi, K. Sugimura
American Journal of Neuroradiology Dec 2017, 38 (12) 2399-2405; DOI: 10.3174/ajnr.A5372
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