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Angiographic outcomes and treatment-related complications
Variables Raw Numbersa No. of Articles 95% CI I2 P Value MCA aneurysm occlusion after flow diversion Overall rate of complete/near-complete occlusion 137/171 = 78.7% 10 67.8–89.7 76.24 <.001 Factors related to aneurysm occlusion Mean age (yr) .262 Complete/near-complete occlusion 53.6 yr 4 47.3–59.8 75% Incomplete occlusion 61.3 yr 48.9–73.5 95% Mean size .614 Complete/near-complete occlusion 7 mm 6 3.6–10.3 83.6% Incomplete occlusion 5.5 mm 0.8–10.1 99% Complete/near-complete occlusion .38 Retreatment 64% 5 33.9–93.4 75.2% vs vs First treatment 73% 63–83.5 0% Complete/near-complete occlusion .307 Prebifurcation (M1–early cortical branches) 88.1% 11 79.6–96.7 0% vs vs Bifurcation aneurysms 77.7% 64.5–89.5 74.92% Complications related to treatment and outcome Overall rate of treatment-related complications 46/213 = 20.7% 11 14–27.5 34.03% .126 Transient or asymptomatic 11.3% 7.6–16.2 vs vs 11 6.8–15.2 Permanent 10.3% Type of complications Ischemic/thromboembolic 16.3% 11 10.1–22.6 36.65% .106 Hemorrhagic 2% 0.2–3.9 0% .958 Iatrogenic (dissection/perforation) 1.8% 0%–1.3.5% 0% .973 Perianeurysmal inflammation 2.6% 0.5–4.7 0% .997 Complications related to discontinuation of antiplatelet therapy 4/46 = 8.7% 11 2.9–20.8 Aneurysm rupture after treatment 1/214 = 0.47% 12 0.1–2.8 Overall rate of good outcome 125/135 = 92.7% 7 86.4–99.1 42.08% .11 Mortality rate 4/213 = 2% 11 0.2–3.9% 0% .929 Note:— vs indicates versus.
↵a Results of meta-analysis.
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